Results 201 to 210 of about 88,042,096 (284)
The FEBS Journal, EarlyView.Sclerostin (SOST) is a multifunctional extracellular modulator of BMP and Wnt signaling. SOST binds with high affinity to fibrillin‐1 and fibrillin‐2, localizing it to fibrillin microfibrils and regulating its extracellular bioavailability. Fibrillin‐bound SOST cannot engage BMP‐7 prodomain (PD) complexes, revealing a competitive mechanism that ...
Annkatrin Correns +11 more
wiley +1 more source
Bone morphogenetic protein 4 (BMP4); noggin (NOG) [PDF]
Science-Business eXchange, 2011 openaire +1 more source
SHIP1 regulates TREM2 signalling and macrophage functions in a hiPSC‐derived model
The FEBS Journal, EarlyView.In this study, we characterised the role of SHIP1 in regulating TREM2 signalling and global microglial myeloid functions using human‐induced pluripotent stem cell (hiPSC)‐derived macrophages. Knockout of SHIP1 (SHIP1 KO) in macrophages decreased inflammatory activation and levels of scavenger receptors. SHIP1 KO macrophages also exhibited reduced TREM2
Kim S. Martin +5 more
wiley +1 more source
Stimulation of Epithelial Sodium Channels in Endothelial Cells by Bone Morphogenetic Protein-4 Contributes to Salt-Sensitive Hypertension in Rats. [PDF]
Oxid Med Cell Longev, 2020 Yang X +10 more
europepmc +1 more source
RLIM‐associated neurodevelopmental disorders: From clinical spectrum to molecular mechanisms
The FEBS Journal, EarlyView.RLIM (RNF12) is an E3 ubiquitin ligase essential for mammalian development. Loss‐of‐function variants cause Tønne–Kalscheuer syndrome, while duplications cause Xq13 duplication syndrome, highlighting RLIM dosage sensitivity. This review summarizes the genetics, clinical features, and molecular mechanisms of RLIM‐associated disorders, integrating ...
Madison Landon +4 more
wiley +1 more source
International Endodontic Journal, EarlyView.ABSTRACT Background The bioactive molecules released from dentine are key to stem‐cell recruitment, proliferation and differentiation in regenerative endodontics. However, there is limited and conflicting information regarding current and potential agents for releasing dentine bioactive molecules for regenerative endodontic procedures.
Arwa Al‐Maswary +4 more
wiley +1 more source
Correction to "CD34dim Cells Identified as Pluripotent Stem Cell-Derived Definitive Hemogenic Endothelium Purified Using Bone Morphogenetic Protein 4". [PDF]
Cell Prolifeuropepmc +1 more source
Impact of long-lasting spontaneous physical activity on bone morphogenetic protein 4 in the heart and tibia in murine model of heart failure. [PDF]
Physiol Rep, 2020 Majerczak J +8 more
europepmc +1 more source
International Journal of Applied Linguistics, EarlyView.ABSTRACT This study examines how epistemic commitment is temporally and syntactically staged across journal tiers in life‐science research writing. Drawing on a 2.3‐million‐word corpus of 320 publications in biochemistry, genetics, and molecular biology, it compares higher‐tier journals with a SCImago Journal Rank (SJR) value of 2.000 or above ...
Ezra Alexander
wiley +1 more source
Journal of Prosthodontics, EarlyView.Abstract Purpose Few studies have explored the bone response in dental implant sites prepared using a piezoelectric device, indicating moderate effectiveness in enhancing secondary stability and osteogenesis. This study seeks to expand our understanding of the changes in biological, clinical, and radiographic parameters, during the initial phases of ...
Gianmario Schierano +8 more
wiley +1 more source