Results 91 to 100 of about 2,491,420 (247)

Avaliação in vitro e in vivo dos efeitos da proteína óssea morfogenética tipo 2 recombinante (rhBMP-2) e de células-tronco derivadas do tecido adiposo humano na osteogênese [PDF]

open access: yes, 2012
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Biotecnologia e Biociências, Florianópolis, 2012Dentre os vários fatores de crescimento que têm sido relatados na literatura para ...
Cruz, Ariadne Cristiane Cabral da
core  

Bone Morphogenetic Proteins and their Receptors

open access: yes, 2006
Bone morphogenetic proteins (BMPs) are important cell–cell signalling molecules that were first identified by their ability to induce cartilage and bone, and subsequently were shown to be multifunctional proteins.
Peter Dijke   +5 more
core   +1 more source

Bone morphogenetic proteins in destructive and remodeling arthritis [PDF]

open access: yes, 2007
Joint destruction and tissue responses determine the outcome of chronic arthritis. Joint inflammation and damage are often the dominant clinical presentation. However, in some arthritic diseases, in particular the spondyloarthritides, joint remodeling is
Luyten, Frank, Lories, Rik
core   +1 more source

Smart Bioinks for 4D Bioprinting: Requirements, Design, and Applications

open access: yesAdvanced Science, EarlyView.
Smart bioinks empower 4D‐bioprinted constructs to dynamically adapt and remodel in response to stimuli, effectively biomimicking native tissues. Artificial Intelligence (AI) and Machine Learning (ML) play a guiding role in their rational design by optimizing relevant properties.
Shangsi Chen   +11 more
wiley   +1 more source

Glypicans Dally and Dally-like control injury-induced allodynia in

open access: yesMolecular Pain, 2019
Over 100 million people are challenged by the effects of chronic pain in the United States alone. This burden also impacts the U.S. economy; 600 billion dollars annually is spent on medical care, medications, and lost productivity in the workplace ...
Courtney L Brann   +2 more
doaj   +1 more source

Bioenergetic Materials for Tissue Regeneration: Modulating Metabolism to Promote Cellular Anabolism

open access: yesAdvanced Science, EarlyView.
Bioenergetic materials (BEMs) modulate cellular metabolism to promote tissue regeneration. Their principal mechanisms of action include metabolic substrate supplementation, metabolic enzyme modulation, organelle transfer, electrical current regulation, redox homeostasis modulation, and oxygen tension modulation.
Yuchen He   +7 more
wiley   +1 more source

CLINICAL APPLICATION OF BONE MORPHOGENETIC PROTEIN ON FRACTURE HEALING PROCESS

open access: yesJournal Orthopaedi and Traumatology Surabaya, 2019
Delayed union or non-union often occurs in bone healing fracture process. The clinical application of Bone Morphogenetic Proteins (BMPs) has helped an increasing number of patients achieve bone regeneration in clinical area lacking simple solutions for ...
Riko Febrian Kunta Adjie
doaj   +1 more source

A Spatiotemporal Single‐Cell Atlas Uncovers Dysregulated ECM Dynamics and Septal Remodeling Arrest in Human Ventricular Septal Defects

open access: yesAdvanced Science, EarlyView.
Integrating single‐cell and spatial transcriptomics reveals human ventricular septal defect (VSD) as a disease of microenvironmental insufficiency and structural remodeling arrest. Attenuated endothelial‐fibroblast crosstalk, alongside downregulated THBS1/TGF‐β1 and MMP2 signaling networks, impairs the endothelial‐to‐mesenchymal transition (EndoMT) and
Xiaoyuan Zhang   +9 more
wiley   +1 more source

GDF9 and BMP15 Expressions and Fine Structure Changes During Folliculogenesis in Polycystic Ovary Syndrome

open access: yesBalkan Medical Journal, 2018
Background: Polycystic ovary syndrome is the most frequently seen endocrine disorder in women of reproductive age with a prevalence of about 10%. Aims: To investigate the efficiency of growth differentiation factor 9 and bone morphogenetic protein 15 ...
Meryem İlkay Karagül1   +4 more
doaj   +1 more source

BMPs: from bone to body morphogenetic proteins

open access: yes, 2010
The family of bone morphogenetic proteins (BMPs) comprises approximately 30 secreted cytokines that signal through transmembrane serine/threonine kinase receptors.
Sieber, C   +3 more
core   +1 more source

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