Results 31 to 40 of about 338,869 (357)
BMP signaling in the development and regeneration of tooth roots: from mechanisms to applications
Short root anomaly (SRA), along with caries, periodontitis, and trauma, can cause tooth loss, affecting the physical and mental health of patients.
Cangwei Liu +7 more
doaj +1 more source
Fe-doped carbon dots: a novel biocompatible nanoplatform for multi-level cancer therapy
Background Tumor treatment still remains a clinical challenge, requiring the development of biocompatible and efficient anti-tumor nanodrugs. Carbon dots (CDs) has become promising nanomedicines for cancer therapy due to its low cytotoxicity and easy ...
Mingxi Yang +11 more
doaj +1 more source
Bone remodelling at a glance [PDF]
The bone remodelling cycle (see Poster panel “The bone remodelling cycle”) maintains the integrity of the skeleton through the balanced activities of its constituent cell types. These are the bone-forming osteoblast, a cell that produces the organic bone matrix and aids its mineralisation ([
Lynne J. Hocking +4 more
openaire +3 more sources
Transplantation of progenitor cells and regeneration enhancement in acute myocardial infarction - (TOPCARE-AMI) [PDF]
Background - Experimental studies suggest that transplantation of blood-derived or bone marrow–derived progenitor cells beneficially affects postinfarction remodeling.
Aicher, A +12 more
core +1 more source
The mechanisms involved in the TNF-mediated deregulated bone remodeling are little appreciated. This review will discuss and summarize the impact of TNF, Notch, and RBP-J signaling on bone remodeling.The integrity of the adult skeleton undergoes constant and dynamic remodeling throughout life to maintain a proper bone homeostasis, which is achieved by ...
Baohong Zhao, Baohong Zhao
openaire +3 more sources
Oxygen is essential for cell survival and tissue regeneration. Scaffolds releasing oxygen have been hypothesized as an ideal strategy for bone repair. However, excessive oxygen supply will disturb the redox balance, lead to oxidative stress, and affect ...
Bin Zhao +11 more
doaj +1 more source
Alendronate treatment results in similar levels of trabecular bone remodeling in the femoral neck and vertebra [PDF]
Introduction Bone turnover suppression in sites that already have a low surface-based remodeling rate may lead to oversuppression that could have negative effects on the biomechanical properties of bone.
Allen, Matthew R. +2 more
core +1 more source
Objective: This study aimed to investigate the regulatory effect of N-isopropylacrylamide-modified polyethyleneimine (PEN)-delivered oligodeoxynucleotide (ODN) MT01 on bone regeneration in vitro and in vivo.Methods: A polyethylenimine (PEI) derivative ...
Qian Zhang +13 more
doaj +1 more source
General analysis of mathematical models for bone remodeling
Bone remodeling is regulated by pathways controlling the interplay of osteoblasts and osteoclasts. In this work, we apply the method of generalized modelling to systematically analyse a large class of models of bone remodeling.
Gross, Thilo +3 more
core +1 more source
Macrophages and Bone Remodeling
ABSTRACTBone remodeling in the adult skeleton facilitates the removal and replacement of damaged and old bone to maintain bone quality. Tight coordination of bone resorption and bone formation during remodeling crucially maintains skeletal mass. Increasing evidence suggests that many cell types beyond osteoclasts and osteoblasts support bone remodeling,
Megan M Weivoda, Elizabeth W Bradley
openaire +2 more sources

