Results 61 to 70 of about 356,262 (352)

Gallium and gallium compounds: New insights into the “Trojan horse” strategy in medical applications

Materials & Design, 2023
Infection, inflammation, tumors, and other illnesses have for a long time posed a major danger to human health and have developed into a global public health issue.
Wenyue Sun, Manlin Qi, Shi Cheng, Chunyan Li, Biao Dong, Lin Wang   +5 more
doaj   +1 more source

Mechanisms of bone remodeling and therapeutic strategies in chronic apical periodontitis [PDF]

, 2022
Luo Xu-tao, Qianxue Wan, Lei Cheng, Ruoshi Xu   +3 more
openalex   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Regulation of FN1 degradation by the p62/SQSTM1-dependent autophagy–lysosome pathway in HNSCC

International Journal of Oral Science, 2020
Epithelial–mesenchymal transition (EMT) is involved in both physiological and pathological processes. EMT plays an essential role in the invasion, migration and metastasis of tumours.
Xinchen Liu, Lin Meng, Xing Li, Daowei Li, Qilin Liu, Yumeng Chen, Xiangwei Li, Wenhuan Bu, Hongchen Sun   +8 more
doaj   +1 more source

Epigenetics and Bone Remodeling [PDF]

Current Osteoporosis Reports, 2017
Bone remodeling is a diverse field of study with many direct clinical applications; past studies have implicated epigenetic alterations as key factors of both normal bone tissue development and function and diseases of pathologic bone remodeling. The purpose of this article is to review the most important recent advances that link epigenetic changes to
Ali, Husain, Matlock A, Jeffries
openaire   +2 more sources

Issues in modern bone histomorphometry [PDF]

, 2011
This review reports on proceedings of a bone histomorphometry session conducted at the Fortieth International IBMS Sun Valley Skeletal Tissue Biology Workshop held on August 1, 2010.
Burr, David B., Dempster, D, Kimmel, DB, Recker, Robert R, Weinstein, RS, Wronski, TJ   +5 more
core   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Identification of cross-talk pathways and PANoptosis-related genes in periodontitis and Alzheimer’s disease by bioinformatics analysis and machine learning

Frontiers in Aging Neuroscience
Background and objectivesPeriodontitis (PD), a chronic inflammatory disease, is a serious threat to oral health and is one of the risk factors for Alzheimer’s disease (AD).
Xiantao Chen, Xiantao Chen, Yifei Dai, Yifei Dai, Yushen Li, Yushen Li, Jiajun Xin, Jiajun Xin, Jiatong Zou, Jiatong Zou, Rui Wang, Rui Wang, Hao Zhang, Hao Zhang, Zhihui Liu, Zhihui Liu   +15 more
doaj   +1 more source

Nanomaterials-mediated on-demand and precise antibacterial therapies

Materials & Design, 2023
Bacterial infection is a series of pathological changes caused by bacteria invading the host and interacting with the body. Nowadays, bacterial infection remains a major public health issue and a severe threat to human life and health.
Shi Cheng, Qihui Wang, Manlin Qi, Wenyue Sun, Kun Wang, Wen Li, Jinying Lin, Biao Dong, Lin Wang   +8 more
doaj   +1 more source

Bone functional remodeling under multi-field loadings [PDF]

, 2007
Bone remodeling process is investigated theoretically and numerically within the framework of the extended adaptive elasticity. The coupling between the internal and surface remodeling is considered for the solution of the bone remodeling process. A semi-
He, Xiaoqiao, Qin, Qing-Hua, Qu, Chuanyong   +2 more
core