Results 61 to 70 of about 2,011,561 (382)
Regulation of FN1 degradation by the p62/SQSTM1-dependent autophagy–lysosome pathway in HNSCC
International Journal of Oral Science, 2020 Epithelial–mesenchymal transition (EMT) is involved in both physiological and pathological processes. EMT plays an essential role in the invasion, migration and metastasis of tumours.
Xinchen Liu +8 more
doaj +1 more source
Advances in mesenchymal stem cell conditioned medium-mediated periodontal tissue regeneration
Journal of Translational Medicine, 2021 Periodontitis is a chronic inflammatory disease that leads to the destruction of both soft and hard periodontal tissues. Complete periodontal regeneration in clinics using the currently available treatment approaches is still a challenge.
Hongbing Lin +9 more
doaj +1 more source
Regulation of Bone Remodeling by Parathyroid Hormone.
Cold Spring Harbor Perspectives in Medicine, 2018 Parathyroid hormone (PTH) exerts profound effects on skeletal homeostasis through multiple cellular and molecular mechanisms. Continuous hyperparathyroidism causes net loss of bone mass, despite accelerating bone formation by osteoblasts.
Marc N. Wein, H. Kronenberg
semanticscholar +1 more source
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Molecular Oncology, EarlyView.Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink +6 more
wiley +1 more source
Research progress on the relationship between occlusal overload and peri-implantitis
口腔疾病防治, 2021 Implant dentures have become the main method for the treatment of dentition defects or complete edentulism. However, due to the lack of periodontal ligament and periodontal ligament proprioceptors, implant dentures have very limited cushioning and ...
JIN Zhuohua +5 more
doaj +1 more source
Role of osteopontin in bone remodeling and orthodontic tooth movement: a review
Progress in orthodontics, 2018 In this review, most of the known and postulated mechanisms of osteopontin (OPN) and its role in bone remodeling and orthodontic tooth movement are discussed based on available literature.
Amarjot Singh +4 more
semanticscholar +1 more source
Destroy to Rebuild: The Connection Between Bone Tissue Remodeling and Matrix Metalloproteinases
Frontiers in Physiology, 2020 Bone is a dynamic organ that undergoes constant remodeling, an energetically costly process by which old bone is replaced and localized bone defects are repaired to renew the skeleton over time, thereby maintaining skeletal health. This review provides a
E. Hardy, C. Fernandez-Patron
semanticscholar +1 more source
The interplay between tissue healing and bone remodeling around immediately loaded tooth replacement implants [PDF]
, 2019 Long-term bone healing/adaptation after a dental implant treatment starts with diffusion of mesenchymal stem cells to the fracture callus and their subsequent differentiation. The healing phase is followed by the bone-remodeling phase. In this work, a mechano-regulatory cellular differentiation model was used to simulate tissue healing around an ...
arxiv +1 more source
Modelling the anabolic response of bone using a cell population model [PDF]
J Theor Biol 307 (2012) 42-52, 2011 To maintain bone mass during bone remodelling, coupling is required between bone resorption and bone formation. This coordination is achieved by a network of autocrine and paracrine signalling molecules between cells of the osteoclast lineage and cells of the osteoblastic lineage.
arxiv +1 more source