Sensors, 2017 Novel boron-containing drugs have recently been suggested as a new class of pharmaceuticals. However, the majority of current boron-detection techniques require expensive facilities and/or tedious pretreatment methods.
Yoshihide Hattori +4 more
doaj +1 more source
Boron encapsulated in a liposome can be used for combinational neutron capture therapy
Nature Communications, 2022 Boron neutron capture therapy is a type of cancer therapy but is associated with insufficient boron delivery and with poor biocompatibility. Here, the authors constructed boronated lipids to generate - boronsome - and show the system can reduce tumour ...
Jiyuan Li +8 more
doaj +1 more source
Radiobiological response of U251MG, CHO-K1 and V79 cell lines to accelerator-based boron neutron capture therapy [PDF]
, 2017 In the current article, we provide in vitro efficacy evaluation of a unique accelerator-based neutron source, constructed at the Budker Institute of Nuclear Physics (Novosibirsk, Russian Federation), for boron neutron capture therapy (BNCT), which is ...
Isobe Tomonori +15 more
core +2 more sources
Boron neutron capture therapy for urological cancers [PDF]
International Journal of Urology, 2022 AbstractBoron neutron capture therapy is based on a nuclear reaction between the nonradioactive isotope boron‐10 and either low‐energy thermal neutrons or high‐energy epithermal neutrons, which generate high linear energy transfer α particles and a recoiled lithium nucleus (7Li) that selectively destroys the DNA helix in tumor cells.
Kiyoshi Takahara +3 more
openaire +2 more sources
The prospects of using IRT-T reactor experimantal facilities for boron neutron capture therapy research [PDF]
, 2012 Investigation on the use of IRT-T research reactor experimental facilities for Boron Neutron Capture Therapy (BNCT) applications was performed by calculating beam parameters at the horizontal channels' exits.
Молодов, П. А. +2 more
core +2 more sources
The basis and advances in clinical application of boron neutron capture therapy
Radiation Oncology, 2021 Boron neutron capture therapy (BNCT) was first proposed as early as 1936, and research on BNCT has progressed relatively slowly but steadily. BNCT is a potentially useful tool for cancer treatment that selectively damages cancer cells while sparing ...
Huifang He +9 more
doaj +1 more source
Boron neutron capture therapy for newly diagnosed glioblastoma [PDF]
, 2009 PurposeThe efficacy, safety, and dose distribution of neutron capture therapy (NCT) were evaluated in 15 patients with newly diagnosed glioblastoma.Methods and materialsSeven patients received intraoperative NCT (protocol-1) and eight patients received ...
Endo Kiyoshi +11 more
core +1 more source
Boron Vehiculating Nanosystems for Neutron Capture Therapy in Cancer Treatment
Cells, 2022 Boron neutron capture therapy is a low-invasive cancer therapy based on the neutron fission process that occurs upon thermal neutron irradiation of 10B-containing compounds; this process causes the release of alpha particles that selectively damage ...
Giorgia Ailuno +7 more
doaj +1 more source
The Birmingham Boron Neutron Capture Therapy (BNCT) project : developments towards selective internal particle therapy [PDF]
, 2011 This paper will review progress on two aspects of the Birmingham BNCT project. Firstly on evaluation of the effects of high and low LET radiations when delivered simultaneously, and secondly on attempts to optimise delivery of the boron carrier compound ...
Boddy, A. +23 more
core +1 more source
Boron distribution in the normal rat brain after intravenous injection of boronophenylalanine-fructose [PDF]
, 2008 Boron neutron capture therapy (BNCT) is an experimental form of radiation therapy for malignant brain tumors and peripheral melanoma. The micro-distribution of the boron compound is critical to determine the radiation effects for both tumors and normal ...
Shibata Yasushi, 柴田 靖
core +1 more source