Results 31 to 40 of about 10,670 (219)

Boron Neutron Capture Therapy: From Nuclear Physics to Biomedicine

Biology, 2021
Boron Neutron Capture Therapy (BNCT) is a binary radiation treatment exploiting a nuclear reaction occurring in tumor cells [...]
Silva Bortolussi, Yuan-Hao Liu, Ignacio Porras   +2 more
doaj   +1 more source

Dicarba-closo-dodecarborane-containing half-sandwich complexes of ruthenium, osmium, rhodium and iridium : biological relevance and synthetic strategies [PDF]

, 2012
This review describes how the incorporation of dicarba-closo-dodecarboranes into half-sandwich complexes of ruthenium, osmium, rhodium and iridium might lead to the development of a new class of compounds with applications in medicine. Such a combination
Barry, Nicolas P. E., Sadler, P. J.
core   +1 more source

Dosimetry for boron neutron capture therapy developed and verified at the accelerator based neutron source VITA

Frontiers in Nuclear Engineering, 2023
The method of boron neutron capture therapy for malignant tumors, proposed in 1936, is beginning to enter clinical practice. The development of dosimetry tools for characterization of therapeutic mixed neutron-photon beam and assessing the patient’s ...
Marina Bikchurina, Timofey Bykov, Ibrahim Ibrahim, Ibrahim Ibrahim, Ibrahim Ibrahim, Anna Kasatova, Dmitrii Kasatov, Iaroslav Kolesnikov, Victoria Konovalova, Victoria Konovalova, Timur Kormushakov, Timur Kormushakov, Alexey Koshkarev, Alexey Koshkarev, Anton Kuznetsov, Anton Kuznetsov, Vyacheslav Porosev, Sergey Savinov, Ivan Shchudlo, Nataliia Singatulina, Nataliia Singatulina, Evgeniia Sokolova, Tatiana Sycheva, Iuliia Taskaeva, Gleb Verkhovod, Sergey Taskaev, Sergey Taskaev   +26 more
doaj   +1 more source

Monte Carlo assessment of boron neutron capture therapy for the treatment of breast cancer [PDF]

Nuclear Technology and Radiation Protection, 2005
For a large number of women who are diagnosed with breast cancer every year the avail able treatment options are effective, though physically and mentally taxing.
Mundy Daniel W., Jevremović Tatjana
doaj   +1 more source

Amino Acid-Based Boron Carriers in Boron Neutron Capture Therapy (BNCT)

Pharmaceutics, 2023
Interest in the design of boronated amino acids has emerged, partly due to the utilization of boronophenylalanine (BPA), one of the two agents employed in clinical Boron Neutron Capture Therapy (BNCT).
Juulia Järvinen, Herkko Pulkkinen, Jarkko Rautio, Juri M. Timonen   +3 more
doaj   +1 more source

Modeling Changes in Measured Conductance of Thin Boron Carbide Semiconducting Films Under Irradiation [PDF]

, 2016
Semiconducting, p-type, amorphous partially dehydrogenated boron carbide films (a-B10C2+x:Hy) were deposited utilizing plasma enhanced chemical vapor deposition (PECVD) onto n-type silicon thus creating a heterojunction diode.
Ianno, Natale J., Nastasi, Michael, Peterson, George G., Wang, Yongqiang   +3 more
core   +2 more sources

Boron delivery for boron neutron capture therapy targeting a cancer-upregulated oligopeptide transporter

Journal of Pharmacological Sciences, 2019
Boron neutron capture therapy (BNCT) is a radiotherapy utilizing the neutron capture and nuclear fission reaction of 10B taken up into tumor cells. The most commonly used boron agent in BNCT, p-borono-l-phenylalanine (BPA), is accumulated in tumors by ...
Junji Miyabe, Ryuichi Ohgaki, Keijiro Saito, Ling Wei, Lili Quan, Chunhuan Jin, Xingming Liu, Suguru Okuda, Shushi Nagamori, Hiroshi Ohki, Kazuo Yoshino, Hidenori Inohara, Yoshikatsu Kanai   +12 more
doaj   +1 more source

Localized nuclear reaction breaks boron drug capsules loaded with immune adjuvants for cancer immunotherapy

Nature Communications, 2023
Boron neutron capture therapy (BNCT) was clinically approved in 2020 and exhibits remarkable tumour rejection in preclinical and clinical studies. It is binary radiotherapy that may selectively deposit two deadly high-energy particles (4He and 7Li ...
Yaxin Shi, Zhibin Guo, Qiang Fu, Xinyuan Shen, Zhongming Zhang, Wenjia Sun, Jinqiang Wang, Junliang Sun, Zizhu Zhang, Tong Liu, Zhen Gu, Zhibo Liu   +11 more
doaj   +1 more source

PK Modeling of L-4-Boronophenylalanine and Development of Bayesian Predictive Platform for L-4-Boronophenylalanine PKs for Boron Neutron Capture Therapy

Pharmaceuticals
L-4-[(10B)]Boronophenylalanine (BPA) is an amino acid analogue with a boron-10 moiety. It is most widely used as a boron carrier in boron neutron capture therapy.
Woohyoung Kim, Ji Yeong Won, Jungyu Yi, Seung Chan Choi, Sang Min Lee, Kyungran Mun, Hyeong-Seok Lim   +6 more
doaj   +1 more source

Gadolinium Neutron Capture Therapy for Cats and Dogs with Spontaneous Tumors Using Gd-DTPA

Veterinary Sciences, 2023
We conducted a clinical veterinary study on neutron capture therapy (NCT) at a neutron-producing accelerator with seven incurable pets with spontaneous tumors and gadolinium as a neutron capture agent (gadolinium neutron capture therapy, or GdNCT ...
Vladimir Kanygin, Alexander Zaboronok, Aleksandr Kichigin, Elena Petrova, Tatyana Guselnikova, Andrey Kozlov, Dmitriy Lukichev, Bryan J. Mathis, Sergey Taskaev   +8 more
doaj   +1 more source