Results 61 to 70 of about 11,682,231 (209)

Molecular Machinery from DNA: Synthetic Biology from the Bottom up [PDF]

Biophysical Journal, 2014
DNA is a wonderful material for nanoscale construction, enabling the creation of synthetic biological systems from the bottom up. Its self-assembly can be programmed using information embedded in base sequence, and its hybridization or hydrolysis can be used as to provide energy for synthetic molecular machinery.
openaire   +2 more sources

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

An Overview on Synthetic Biology: its Classification, Engineering Approaches, and Applications of Synthetic Biology [PDF]

, 2023
Synthetic biology is an interdisciplinary field that focuses on living organisms and systems, employing engineering techniques to create innovative biological devices, systems, and components.
Muhammad Hamza Awan, Nimra Tabassum, Areeba Afzal, Soha Fatima, Hassaan Bin Sajid, Muhammad Asif Raheem   +5 more
core   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

The Transnational Governance of Synthetic Biology: Scientific uncertainty, cross-borderness and the ‘art’ of governance. For the Royal Society Science Policy Centre (UK). [PDF]

, 2011
Synthetic biology is a new field of research that aims to 'make biology easier to engineer'. Some claim that it could revolutionise biotechnology to deliver applications for the energy, medical and agricultural sectors. However there are concerns about
Zhang, Joy Yueyue, Rose, Nikolas, Rose, N., Marris, C., Marris, Claire, Zhang, J., Zhang, Joy Y.   +6 more
core  

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source

Pepticombisomes: Biomimetic Vesicles Crafted From Recombinant Supercharged Polypeptides with Uniformly Distributed Side‐Chains

Advanced Science
Cell membranes play a key role in bottom‐up synthetic biology, as they enable interaction control, transport, and other essential functions. These ultra‐thin, flexible, yet stable structures form through the self‐assembly of lipids and proteins.
Dominik Söder, Melina Schadt, Vladislav S. Petrovskii, Tamás Haraszti, Khosrow Rahimi, Igor I. Potemkin, Nina Yu. Kostina, Cesar Rodriguez‐Emmenegger, Andreas Herrmann   +8 more
doaj   +1 more source

Synthetic biology

, 2009
There is currently much excitement surrounding the rapidly growing discipline of synthetic biology, which utilizes the design and construction principles of engineering to develop, evolve and standardize biological components and systems. This systematic
Ali Tavassoli, Tavassoli, Ali
core   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Artificial cell system as a tool for investigating pattern formation mechanisms of intracellular reaction-diffusion waves

Biophysics and Physicobiology
Intracellular positional information is crucial for the precise control of biological phenomena, including cell division, polarity, and motility. Intracellular reaction-diffusion (iRD) waves are responsible for regulating positional information within ...
Sakura Takada, Kei Fujiwara
doaj   +1 more source