Results 11 to 20 of about 48,590 (264)
Immunogenicity of botulinum toxin [PDF]
Archives of Plastic Surgery, 2022 Botulinum toxin treatment is the most common non-surgical cosmetic treatment. Although there are many available treatments using botulinum toxin, their effects are temporary and repeated injections are required. These frequent injections can trigger an immunological response. In addition, botulinum toxin acts as an antigen in the body; thus, its effect
Syeo Young Wee, Eun Soo Park
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Journal of Rehabilitation Medicine, 2020 Objective: To investigate changes in hemiparetic gait parameters after treatment of elbow flexor spasticity with botulinum neurotoxin (BoNT) injection and adjunctive casting. Design: Prospective case series.
Supun Kotteduwa Jayawarden +6 more
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Evolutionary Features in the Structure and Function of Bacterial Toxins
Toxins, 2019 Toxins can function both as a harmful and therapeutic molecule, depending on their concentrations. The diversity in their function allows us to ask some very pertinent questions related to their origin and roles: (a) What makes them such effective ...
Raj Kumar +5 more
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Vitamin D (steroid hormone) and the nervous system diseases (literature review)
Сибирский научный медицинский журнал, 2020 The present review aims to summarize the activities of vitamin D effects on the nervous system and to clarify a vitamin D role in brain diseases, in the pathogenesis or as a serum biomarker for the disease development and severity. Objective: correlation
D. A. Novotnyy +7 more
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Indian Journal of Dermatology, 2010 Botulinum toxin, one of the most poisonous biological substances known, is a neurotoxin produced by the bacterium Clostridium botulinum. C. botulinum elaborates eight antigenically distinguishable exotoxins (A, B, C(1), C(2), D, E, F and G). All serotypes interfere with neural transmission by blocking the release of acetylcholine, the principal ...
Nigam P, Nigam Anjana
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Rapid eye movement sleep behavior disorder: modern concept and Parkinson’s disease correlation [PDF]
Анналы клинической и экспериментальной неврологииThis review describes the association between rapid eye movement (REM) sleep behavior disorder (RBD) and synucleinopathies, primarily Parkinson's disease.
Diana M. Khasanova +3 more
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Quality of life at cervical distonia
Бюллетень сибирской медицины, 2020 The aim of the study was to study the physical and psychological components regarding the quality of life of patients with cervical dystonia.Material and methods. 170 respondents were examined. The main group included 120 patients with cervical dystonia,
O. A. Druzhinina +2 more
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Health and Society, 2022 Botulinum neurotoxins (BoNT) are toxins produced by bacteria of the genus Clostridium botulinum and are considered as the most potent toxins nowadays. Firstly, known as a food poison, later explored as a biological weapon and currently considered a great therapeutic resource. Seven different BoNT serotypes (A-G) have already been identified. Among them,
Bruna Luiza Ribeiro de Almeida +2 more
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Recombinant botulinum neurotoxin serotype A1 in vivo characterization
Pharmacology Research & Perspectives, 2021 Clinically used botulinum neurotoxins (BoNTs) are natural products of Clostridium botulinum. A novel, recombinant BoNT type A1 (rBoNT/A1; IPN10260) has been synthesized using the native amino acid sequence expressed in Escherichia coli and has previously
Cindy Périer +13 more
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Centaur antibodies: Engineered chimeric equine-human recombinant antibodies
Frontiers in Immunology, 2022 Hyper-immune antisera from large mammals, in particular horses, are routinely used for life-saving anti-intoxication intervention. While highly efficient, the use of these immunotherapeutics is complicated by possible recipient reactogenicity and limited
Ronit Rosenfeld +16 more
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