Results 111 to 120 of about 3,092 (212)

Clin Infect Dis [PDF]

BackgroundBotulism is a rare, life-threatening paralytic illness. Equine-derived heptavalent botulinum antitoxin (HBAT), the only currently available treatment for noninfant botulism in the United States, was licensed in 2013.

core  

Botulism Fact sheet, July 2015 [PDF]

, 2015
Botulism is a rare but serious muscle-paralyzing illness caused by a nerve toxin (botulinum toxin) produced by the bacterium Clostridium botulinum.

core  

Monoclonal Antibodies that Inhibit the Proteolytic Activity of Botulinum Neurotoxin Serotype/B

Toxins, 2015
Existing antibodies (Abs) used to treat botulism cannot enter the cytosol of neurons and bind to botulinum neurotoxin (BoNT) at its site of action, and thus cannot reverse paralysis.
Yongfeng Fan, Jianbo Dong, Jianlong Lou, Weihua Wen, Fraser Conrad, Isin N. Geren, Consuelo Garcia-Rodriguez, Theresa J. Smith, Leonard A. Smith, Mengfei Ho, Melissa Pires-Alves, Brenda A. Wilson, James D. Marks   +12 more
doaj   +1 more source

Botulism Outbreak in a Family after Ingestion of Locally Produced Cheese

Iranian Journal of Medical Sciences, 2017
Botulism is one of the most important foodborne diseases and is caused by Clostridium botulinum toxin. The main manifestations are flaccid muscle paralysis and cranial nerve palsies.
Shahram Rafie, Shokrollah Salmanzadeh, Asieh Mehramiri, Adel Nejati   +3 more
doaj  

Design and evaluation of mRNA encoding recombinant neutralizing antibodies for botulinum neurotoxin type B intoxication prophylaxis

Human Vaccines & Immunotherapeutics
Among all natural and synthetic toxins, botulinum neurotoxins (BoNTs), produced by Clostridium botulinum in an anaerobic environment, are the most toxic polymer proteins.
Gulisaina Qiaerxie, Yujia Jiang, Gege Li, Zhixin Yang, Feng Long, Yunzhou Yu, Jian Sheng Lu, Peng Du, Yong Cui   +8 more
doaj   +1 more source

Iatrogenic botulism cases after gastric and axillary application of botulinum toxin and review of literature

Journal of Infection in Developing Countries
Introduction: Iatrogenic botulism is a rare, serious disease that progresses with descending paralysis and develops after cosmetic or therapeutic botulinum toxin-A (BoNT-A) application.
Fatma Eser, İmran Hasanoğlu, Bircan Kayaaslan, Ayşe Kaya Kalem, Şule Bilen, Gürdal Orhan, Rahmet Güner   +6 more
doaj   +1 more source

A Novel Botulinum Neurotoxin, Previously Reported as Serotype H, Has a Hybrid-Like Structure With Regions of Similarity to the Structures of Serotypes A and F and Is Neutralized With Serotype A Antitoxin [PDF]

, 2015
Susan E. Maslanka, Carolina Lúquez, Janet K. Dykes, William H. Tepp, Christina L. Pier, Sabine Pellett, Brian H. Raphael, Suzanne R. Kalb, John R. Barr, Agam K. Rao, Eric A. Johnson   +10 more
openalex   +1 more source

Evaluation and isolation of Clostridium botulinum type E from fresh and smoked Cyprinus carpio, Rutilus frisii kutum and Hypophtalmicthys molitrix

‬‭Majallah-i ̒Ilmī-i Shīlāt-i Īrān, 1999
In this study experiments were conducted to evaluate Clostridium botulinum type E in fresh and smoked Cyprinus carpio (60 samples) Rutilus frisii kutum (60 samples) and Hypophthalmichthys molitrix (60 samples). One hundred and eighty samples of fish were
R. Safari; I. Khandaghi
doaj  

Contagious Weakness in an Elderly Couple with Neurologic Emergencies [PDF]

, 2011
We present an unusual neurologic emergency in an elderly male patient. Given his presentation and risk factors, we presumed the initial symptoms to be secondary to a cerebrovascular accident.
Baban, Kandan, Field, Adam G., Garg, Vikram K., Grudko, Kenneth, Matthews, Cari E., Sanyal, Pallabi   +5 more
core   +2 more sources

Wound Botulism in Injection Drug Users: Time to Antitoxin Correlates with Intensive Care Unit Length of Stay [PDF]

, 2009
Objectives: We sought to identify factors associated with need for mechanical ventilation (MV), length of intensive care unit (ICU) stay, length of hospital stay, and poor outcome in injection drug users (IDUs) with wound botulism (WB).Methods: This is a
Cook, Matthew D., Holmes, James F., Offerman, Steven R., Schaefer, Melissa, Thundiyil, Joseph G.   +4 more
core   +1 more source