Results 81 to 90 of about 3,092 (212)

The enemy at the gate: Botulism. [PDF]

open access: yesTurk J Emerg Med
Botulism, caused by Clostridium botulinum, continues to pose a significant threat to public health. This review explores the historical context and contemporary relevance of botulism, emphasizing its potential lethality and evolving medical applications.
Taşkın Ö, Akpınar AA.
europepmc   +2 more sources

Practical approach to the child presenting with acute generalised weakness

open access: yesJournal of Paediatrics and Child Health, Volume 60, Issue 2-3, Page 41-46, February-March 2024.
Acute generalised muscle weakness in children is a paediatric emergency with a broad differential diagnosis. A careful history and neurologic examination guides timely investigation and management. We review some of the more common causes of acute generalised muscle weakness in children, highlighting key history and examination findings, along with an ...
Rebecca Leung, Eppie M Yiu
wiley   +1 more source

The Potential of Single‐Chain Variable Fragment Antibody: Role in Future Therapeutic and Diagnostic Biologics

open access: yesJournal of Immunology Research, Volume 2024, Issue 1, 2024.
The advancement of genetic engineering has revolutionized the field of immunology by allowing the utilization of intrinsic antibody structures. One of the biologics that are being produced by recombinant antibody technology is single‐chain fragments variable (scFv).
Getachew Gezehagn Kussia   +2 more
wiley   +1 more source

Two-family outbreak of botulism associated with the consumption of smoked ribs in Sichuan Province, China [PDF]

open access: yes, 2015
SummaryBackgroundOn September 22, 2013, two patients from Sichuan Province, China presented with symptoms of food-borne botulism, a rare but fatal illness caused by the consumption of foods containing Clostridium botulinum neurotoxins ...
Chen, Xueping   +4 more
core   +2 more sources

From Rarity to Recognition: Infantile Botulism and the Broad Spectrum of Differential Diagnoses

open access: yesCase Reports in Pediatrics, Volume 2024, Issue 1, 2024.
This case illustrates a 5‐week‐old girl who presented with decreased activity, decreased feeds, poor suck, weak cry, lethargy, hypotonia, and areflexia. The child was found to have infant botulism. The case demonstrates the importance of a full history and broad differential in an ill‐appearing infant.
Matthew C. Authement   +4 more
wiley   +1 more source

Bioterrorism [PDF]

open access: yes, 2006
Terrorism preparedness is a highly specific component of general emergency preparedness. In addition to the unique pediatric issues involved in general emergency preparedness, terrorism preparedness must consider several additional issues, including the ...
Markenson, David, Redlener, Irwin E.
core   +2 more sources

Camelid VHHs Fused to Human Fc Fragments Provide Long Term Protection Against Botulinum Neurotoxin A in Mice

open access: yesToxins, 2019
The bacterium Clostridium botulinum is the causative agent of botulism—a severe intoxication caused by botulinum neurotoxin (BoNT) and characterized by damage to the nervous system. In an effort to develop novel C.
Svetlana A. Godakova   +10 more
doaj   +1 more source

Identification of Human Proteins vulnerable to multiple Organisms and their disease associations [PDF]

open access: yesarXiv, 2016
While most studies emphasize on certain aspects of Pathogen-Host Interactions (PHI), such as the preferential attachment of bacteria or virus to its human receptor homolog, studies have attempted to methodically classify interactions among pathogenic proteins and their host proteins.
arxiv  

Biological Terrorism [PDF]

open access: yes, 2008
In the aftermath of the September 11, 2001 attacks and the subsequent mail-borne anthrax attack of October 2001, it has become dear that health care providers may be called upon to respond to victims of terrorism. Biological terrorism (BT), in particular,
Centers for Disease Control and Prevention   +4 more
core   +2 more sources

Production of monoclonal antibodies against botulinum neurotoxin in Nicotiana benthamiana. [PDF]

open access: yesHum Vaccin Immunother
Botulism is a fatal neurologic disease caused by the botulinum toxin (BoNT) produced by Clostridium botulinum. It is a rare but highly toxic disease with symptoms, such as cramps, nausea, vomiting, diarrhea, dysphagia, respiratory failure, muscle ...
Sangprasat K   +6 more
europepmc   +2 more sources

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