Results 61 to 70 of about 2,075 (191)

Adverse Drug Reaction Study of Botulinum Toxin‐A in the Real World

Journal of Cosmetic Dermatology, Volume 25, Issue 6, June 2026.
ABSTRACT Background Despite the increasing use of botulinum toxin type A (BoNT‐A) in aesthetic and therapeutic applications, its real‐world adverse drug reaction (ADR) profile remains incompletely characterized. Current evidence relies largely on small‐scale clinical observations rather than large, systematic analyses.
Jiaxu Gu, Yue Sun, Kexin Chen, Jieyi Wang, Bingcheng Lu, Hongqiang Xie, Xiaoming Liu, Cong Huang, Xingling Jian, Bo Yu   +9 more
wiley   +1 more source

A human bispecific antibody neutralizes botulinum neurotoxin serotype A [PDF]

, 2023
Botulinum neurotoxin (BoNT) shows high lethality and toxicity, marking it as an important biological threat. The only effective post-exposure therapy is botulinum antitoxin; however, such products have great potential for improvement. To prevent or treat
Lei Chen, Jiansheng Lu, Yunzhou Yu, Zhixin Yang, Xuyang Liu, Rong Wang, Jiazheng Guo, Peng Du, Fujia Liu, Yujia Jiang, Zhiying Li   +10 more
core   +1 more source

Clinical characteristics and predictors of prolonged hospitalization in patients with cosmetic botulinum toxin poisoning: a retrospective cohort study

Frontiers in Medicine
BackgroundThe increasing cosmetic use of botulinum toxin has been accompanied by poisoning events related to inappropriate administration, including excessive dosing, unapproved or unverifiable products, self-injection, and procedures performed outside ...
Yu-quan Chen, Yi-fan Ye, Mei-wen Xie, Yu-qiang Lin, Zhi-qian Yang, Zhi Wang   +5 more
doaj   +1 more source

Botulism after intragastric botulinum toxin injections for weight reduction [PDF]

, 2023
Although-considering the risk-benefit ratio-botulinum neurotoxin A (BoNT/A) is unequivocally recommended to treat severe neurological diseases such as dystonia, this has not yet been determined for its endoscopic intragastric injection aimed at weight ...
Wunderlich, Gilbert, Gilbert Wunderlich, Rueger, Maria Adele, Demir, Seda, Christina Hennen, Gereon Rudolf Fink, Michael Thomas Barbe, Hennen, Christina, Christoph Hüser, Barbe, Michael Thomas, Böll, Boris, Seda Demir, Haidar Salimi Dafsari, Maria Adele Rueger, Boris Böll, Fink, Gereon Rudolf, Hüser, Christoph, Dafsari, Haidar Salimi   +17 more
core   +1 more source

A BEVERAGE-BORNE ATTACK WITH BOTULINUM TOXIN [PDF]

, 2019
Terrorists contaminated beer tanks of an amusement park supply chain with Botulinum toxin. The amusement park delivers beer to its restaurants and coffee shops by a pipeline network supplied from beer tanks which are fed by tanker-trucks. There are 30000
Chen, Wanying, Guinet, A.
core   +4 more sources

A cell-based alternative to the mouse potency assay for pharmaceutical type E botulinum antitoxins

ALTEX, 2021
The pharmacopeia mouse neutralization assay (PMNA) is the standard method for determining the potency of phar­maceutical botulinum antitoxins. However, a PMNA requires a large number of mice, and, thus, an alternative in vitro method to replace it is needed.
Eran, Diamant, Amram, Torgeman, Eyal, Epstein, Adva, Mechaly, Alon Ben, David, Lilach, Levin, Arieh, Schwartz, Eyal, Dor, Meni, Girshengorn, Ada, Barnea, Ohad, Mazor, Ran, Zichel   +11 more
openaire   +3 more sources

Oral proton‐reprogrammed nanomedicine to break the inflammatory bowel disease‐Clostridium difficile infection vicious cycle

iMeta, Volume 5, Issue 1, February 2026.
Research on the mechanism of OPR restoring intestinal epithelial cell (IEC) structure and function in inflammatory bowel disease (IBD) treatment. (A) Schematic diagram of OPR structure and the rate of GP release under different conditions. (B) Schematic diagram of OPR targeting IBD colonic lesions through charge interaction.
Wensheng Chen, Yuntao Zhang, Jue Wang, Yiming Li, Hao Wu, Qiong Huang, Wei Wu, Kelong Ai   +7 more
wiley   +1 more source

Intestinal Toxemia Botulism in 3 Adults, Ontario, Canada, 2006–2008

Emerging Infectious Diseases, 2012
Five cases of intestinal toxemia botulism in adults were identified within an 18-month period in or near Toronto, Ontario, Canada. We describe findings for 3 of the 5 case-patients.
Yolanda D. Sheppard, Dean Middleton, Yvonne Whitfield, Felix Tyndel, Shariq Haider, Jamie Spiegelman, Richard H. Swartz, Mark P. Nelder, Stacey L. Baker, Lisa Landry, Ross MacEachern, Sherri Deamond, Lorrie Ross, Garth Peters, Michelle Baird, David Rose, Greg Sanders, John W. Austin   +17 more
doaj   +1 more source

Type C botulism outbreak in free-ranging waterfowl in Goiás

Pesquisa Veterinária Brasileira, 2022
: Botulism is generally a fatal disease caused by ingestion of neurotoxins produced by Clostridium botulinum. The present study describes the epidemiological, clinical, and laboratory aspects of a type C botulism outbreak in free-living aquatic birds ...
Andressa S. Martins, Tamires A. Silva, Isabella C.C.R. Rosa, Alexia G.F. Oliveira, Márcio P. Oliveira, Júlia R. Saraiva, Iveraldo S. Dutra, Ana Carolina Borsanelli   +7 more
doaj   +1 more source

Clostridium BotulinumTypes A and B Toxin-Antitoxin Reactions [PDF]

Journal of Hygiene, 1955
SummaryC. botulinumtypes A and B toxins required larger amounts of antitoxin for neutralization when fractions of the test dose of toxin were used than would be expected.The degree of this dilution effect, i.e. the dilution ratio, varied with different sera.
openaire   +2 more sources