Results 71 to 80 of about 33,694 (186)

Botulinum Neurotoxins: History, Mechanism, and Applications. A Narrative Review

Journal of Neurochemistry, Volume 169, Issue 8, August 2025.
Botulinum neurotoxins (BoNTs), produced by Clostridium botulinum, bind irreversibly to presynaptic cholinergic nerve terminals and exploit a zinc‐dependent mechanism to cleave SNARE proteins, blocking acetylcholine release and causing flaccid paralysis.
Arik Monash, Joseph Tam, Osnat Rosen, Hermona Soreq   +3 more
wiley   +1 more source

Opinion of the French Agency for Food, Environmental and Occupational Health & Safety (ANSES) on defining pathogenic strains of Shiga toxin‐producing Escherichia coli

Food Risk Assess Europe, Volume 3, Issue 3, July 2025.
ABSTRACT Shiga toxin‐producing Escherichia coli (STEC) are pathogenic E. coli strains that have been associated with a wide range of human clinical illness ranging from mild diarrhoea to bloody diarrhoea (BD) and haemolytic uremic syndrome (HUS). In its opinion of 18 May 2017, the French Agency for Food, Environmental and Occupational Health and Safety
Philippe Fravalo, Frédéric Auvray, Mickaël Boni, Frédéric Borges, Gilles Bornert, Frédéric Carlin, Catherine Chubilleau, Monika Coton, Georges Daube, Noémie Desriac, Florence Dubois‐Brissonnet, Michel Federighi, Michel Gautier, Michèle Gourmelon, Sandrine Guillou, Stéphane Guyot, Didier Hilaire, Nathalie Jourdan‐da Silva, Claire Le Henaff‐Le Marrec, Sandra Martin‐Latil, Jeanne‐Marie Membré, Eric Oswald, Nadia Oulahal, Pascal Piveteau, Sabine Schorr‐Galindo, Régine Talon, Isabelle Villena, Aurélie Cointe, Mickael Desvaux, Gabrielle Jones, Patricia Mariani‐Kurdjian, Frédérique Audiat‐Perrin, Laurent Guillier, Pauline Kooh   +33 more
wiley   +1 more source

Wearable Temperature Sensor Enhanced Volatilomics Technique for Swift and Convenient Detection of Latrogenic Botulism

Advanced Science, Volume 12, Issue 6, February 10, 2025.
A wearable temperature sensor enhanced volatilomics technique is developed to facilitate the rapid and convenient prediction of potential physical discomfort following botulinum neurotoxin (BoNT) injection. Through simultaneously monitoring the variation of body temperature and breath signals, this innovative strategy achieves an accuracy exceeding 91 ...
Xiaoyang Li, Yufei Yan, Chenyi Hu, Jing Wang, Jinlin Wang, Hao Yang, Daxiang Cui, Wenwen Xin, Shan Gao, Han Jin   +9 more
wiley   +1 more source

Double Sandwich ELISA Modified Method for the Detection of Clostridium Botulinum Type E [PDF]

Journal of Fasa University of Medical Sciences, 2013
Background & Objective: A very small amount of botulinum toxin can cause death and on the other hand, there is no cure for its poison other than antitoxin.
Mohammad Ebrahim minaei, Mojtaba Saadati
doaj   +1 more source

CLOSTRIDIUM BOTULINUM TYPE B TOXOIDS

, 1947
Fluid and alum-precipitated C. botulinum Type B toxoids were prepared by methods very similar to those used in the production of Type A toxoid, as described in a preceding paper.
E. F. Pallister, Christine E. Rice, L. C. Smith, G. B. Reed   +3 more
core   +1 more source

Iatrogenic Botulism After Cosmetic Use of Botulinum Toxin‐A: A Case Series

Clinical Case Reports, Volume 13, Issue 1, January 2025.
ABSTRACT Botulism symptoms after cosmetic botulinum toxin‐A (BTX‐A) injections happen very rarely, and it needs careful attention since it can be life‐threatening. Hence, it is advised to meticulously check the technique, dose, and authenticity of the BTX‐A before injections to reduce the adverse effects.
Mohammad Asadi, Shahin Shadnia, Babak Mostafazadeh, Peyman Erfan Talab Evini, Faraz Zandieh, Mitra Rahimi   +5 more
wiley   +1 more source

Detection of Botulinum Type E Toxin in Channel Catfish with Visceral Toxicosis Syndrome Using Catfish Bioassay and Endopep Mass Spectrometry

, 2007
Visceral toxicosis of catfish (VTC) is a syndrome characterized by sudden mortality in apparently healthy market- and brooder-sized catfish ( Ictalurus punctatus).
Patricia S. Gaunt, Suzanne R. Kalb, John R. Barr   +2 more
core   +1 more source

Investigating Avian Neglect and Welfare Violations: Case Studies in South Korea

Case Reports in Veterinary Medicine, Volume 2025, Issue 1, 2025.
This paper investigates three significant cases of avian welfare violations in South Korea, emphasizing the detrimental effects of neglect and inadequate management practices. The first case concerns the mass mortality of birds in a Seoul park due to methomyl poisoning. The second case focuses on a botulism outbreak occurring on a quail farm. The third
Goun Park, JaeKyeom Kim, Chunghyun Kim, Isabel Pires   +3 more
wiley   +1 more source

Report of the Scientific Committee of the Spanish Agency for Food Safety and Nutrition (AESAN) on the risk assessment of botulism resulting from the consumption of vacuum‐packed or modified atmosphere‐packed foods

Food Risk Assess Europe, Volume 3, Issue 1, January 2025.
Abstract Foodborne botulism is caused by the ingestion of a neurotoxin (BoNT) primarily produced by Clostridium botulinum. This bacterium is classified into six phenotypic Groups, with Groups I and II being associated with human disease. BoNT are divided into seven main types with different antigenic potentials, of which types A, B, E, and F are ...
María Dolores Rodrigo Aliaga, Rosa María Capita González, Baltasar Mayo Pérez, Gloria Sánchez Moragas, Antonio Valero Díaz   +4 more
wiley   +1 more source

A Novel Rabbit Spirometry Model of Type E Botulism and Its Use for the Evaluation of Postsymptom Antitoxin Efficacy

, 2018
Botulinum neurotoxins (BoNTs), the most poisonous substances known in nature, pose significant concern to health authorities. The only approved therapeutic for botulism is antitoxin.
Arnon Tal, Amir Rosner, Eran Diamant, Alon Ben David, Amram Torgeman, Ran Zichel, Avi Pass, Osnat Rosen, Ada Barnea   +8 more
core   +1 more source