Results 51 to 60 of about 379 (143)

Metabolic Origin, Role and Fate of the Denaturant Guanidine

Microbial Biotechnology, Volume 18, Issue 11, November 2025.
The origin of metabolic guanidine is largely a mystery. We suggest it is created when guanine‐containing nucleotides are oxidised by molecular oxygen instead of being broken down into urea as purines normally would. Guanidine may act as a signal to help cells control the level of reactive oxygen species.
Antoine Danchin, Victor de Lorenzo, Pablo Iván Nikel, Conghui You   +3 more
wiley   +1 more source

In-Vivo and In-Vitro Studies of the Effect of Specific Antitoxin on the Phagocytosis of Cells of Clostridium Botulinum Type A [PDF]

Journal of Medical Microbiology, 1973
Summary The conversion of heat-resistant spores of Clostridium botulinum type A into germinated heat-sensitive cells in the peritoneal cavity of mice has been observed. This in-vivo germination of spores was depressed in mice passively immunised with type-A botulinal antitoxin.
J B, Suzuki, N, Grecz
openaire   +2 more sources

Botulinum Neurotoxins: History, Mechanism, and Applications. A Narrative Review

Journal of Neurochemistry, Volume 169, Issue 8, August 2025.
Botulinum neurotoxins (BoNTs), produced by Clostridium botulinum, bind irreversibly to presynaptic cholinergic nerve terminals and exploit a zinc‐dependent mechanism to cleave SNARE proteins, blocking acetylcholine release and causing flaccid paralysis.
Arik Monash, Joseph Tam, Osnat Rosen, Hermona Soreq   +3 more
wiley   +1 more source

Iatrogenic botulinum Toxin Type A poisoning with persistent unilateral vocal cord paralysis: a case report and clinical implications

Frontiers in Pharmacology
With the continuous advancement of medical aesthetic technologies, botulinum toxin injection has emerged as a prevalent method for wrinkle removal and facial enhancement. However, improper administration can result in botulism incidents.
Shizhao Xiang, Yu Du, Yu Du
doaj   +1 more source

Opinion of the French Agency for Food, Environmental and Occupational Health & Safety (ANSES) on defining pathogenic strains of Shiga toxin‐producing Escherichia coli

Food Risk Assess Europe, Volume 3, Issue 3, July 2025.
ABSTRACT Shiga toxin‐producing Escherichia coli (STEC) are pathogenic E. coli strains that have been associated with a wide range of human clinical illness ranging from mild diarrhoea to bloody diarrhoea (BD) and haemolytic uremic syndrome (HUS). In its opinion of 18 May 2017, the French Agency for Food, Environmental and Occupational Health and Safety
Philippe Fravalo, Frédéric Auvray, Mickaël Boni, Frédéric Borges, Gilles Bornert, Frédéric Carlin, Catherine Chubilleau, Monika Coton, Georges Daube, Noémie Desriac, Florence Dubois‐Brissonnet, Michel Federighi, Michel Gautier, Michèle Gourmelon, Sandrine Guillou, Stéphane Guyot, Didier Hilaire, Nathalie Jourdan‐da Silva, Claire Le Henaff‐Le Marrec, Sandra Martin‐Latil, Jeanne‐Marie Membré, Eric Oswald, Nadia Oulahal, Pascal Piveteau, Sabine Schorr‐Galindo, Régine Talon, Isabelle Villena, Aurélie Cointe, Mickael Desvaux, Gabrielle Jones, Patricia Mariani‐Kurdjian, Frédérique Audiat‐Perrin, Laurent Guillier, Pauline Kooh   +33 more
wiley   +1 more source

A severe case of iatrogenic botulism associated with COVID-19 infection

Heliyon
Background: The botulinum toxin is an extremely potent substance that impacts the nervous system. There has been a rise in cases of medical poisoning associated with it, particularly in the field of plastic and aesthetic procedures, in recent years. Case
Qian Ma, Guang-Jing Liu, Shuang Wang, Wen-Di Wang, Ning Liu, Che-Jiang Wang, Xiao-Bing Li   +6 more
doaj   +1 more source

A Novel Rabbit Spirometry Model of Type E Botulism and Its Use for the Evaluation of Postsymptom Antitoxin Efficacy

, 2018
Botulinum neurotoxins (BoNTs), the most poisonous substances known in nature, pose significant concern to health authorities. The only approved therapeutic for botulism is antitoxin.
Arnon Tal, Amir Rosner, Eran Diamant, Alon Ben David, Amram Torgeman, Ran Zichel, Avi Pass, Osnat Rosen, Ada Barnea   +8 more
core   +1 more source

Wearable Temperature Sensor Enhanced Volatilomics Technique for Swift and Convenient Detection of Latrogenic Botulism

Advanced Science, Volume 12, Issue 6, February 10, 2025.
A wearable temperature sensor enhanced volatilomics technique is developed to facilitate the rapid and convenient prediction of potential physical discomfort following botulinum neurotoxin (BoNT) injection. Through simultaneously monitoring the variation of body temperature and breath signals, this innovative strategy achieves an accuracy exceeding 91 ...
Xiaoyang Li, Yufei Yan, Chenyi Hu, Jing Wang, Jinlin Wang, Hao Yang, Daxiang Cui, Wenwen Xin, Shan Gao, Han Jin   +9 more
wiley   +1 more source

Iatrogenic Botulism After Cosmetic Use of Botulinum Toxin‐A: A Case Series

Clinical Case Reports, Volume 13, Issue 1, January 2025.
ABSTRACT Botulism symptoms after cosmetic botulinum toxin‐A (BTX‐A) injections happen very rarely, and it needs careful attention since it can be life‐threatening. Hence, it is advised to meticulously check the technique, dose, and authenticity of the BTX‐A before injections to reduce the adverse effects.
Mohammad Asadi, Shahin Shadnia, Babak Mostafazadeh, Peyman Erfan Talab Evini, Faraz Zandieh, Mitra Rahimi   +5 more
wiley   +1 more source

Detection of Botulinum Type E Toxin in Channel Catfish with Visceral Toxicosis Syndrome Using Catfish Bioassay and Endopep Mass Spectrometry

, 2007
Visceral toxicosis of catfish (VTC) is a syndrome characterized by sudden mortality in apparently healthy market- and brooder-sized catfish ( Ictalurus punctatus).
Patricia S. Gaunt, Suzanne R. Kalb, John R. Barr   +2 more
core   +1 more source