Results 51 to 60 of about 33,694 (186)

The light chain but not the heavy chain of botulinum A toxin inhibits exocytosis from permeabilized adrenal chromaffin cells [PDF]

open access: yes, 1989
The heavy and light chains of botulinum A toxin were separated by anion exchange chromatography. Their intracellular actions were studied using bovine adrenal chromaffin cells permeabilized with streptolysin O.
M. Gratzl   +9 more
core   +1 more source

Botulinum Toxin as Preventive Treatment for Migraine: A Randomized Double-Blind Study [PDF]

open access: yes, 2009
Aim: To determine if botulinum toxin type A (BoNT-A) injections can reduce the frequency and severity of migraines. Methods: Patients (n = 127) were randomized to receive placebo or two doses of BoNT-A (Dysport (R)). The primary endpoint was reduction in
Toelle, Thomas   +13 more
core   +1 more source

Neurotropic Effect of Botulinum Toxin and the Potential of Specific Serum Therapy in Botulism (Review)

open access: yesБезопасность и риск фармакотерапии
INTRODUCTION. The outbreak of foodborne botulism that occurred in Russia in June 2024 once again demonstrated the danger of this rather rare but severe infectious disease caused by ingesting botulinum neurotoxin.
E. M. Eliseeva   +2 more
doaj   +1 more source

BOTOX injection to treat strabismus after infant botulism type B infection

open access: yesAmerican Journal of Ophthalmology Case Reports, 2020
Purpose: The significance of botulinum toxin to ophthalmologists is twofold. Botulism, a medical emergency, frequently presents with ocular findings including blurred vision, diplopia, ptosis, and photophobia as a result of the neurotoxin produced by ...
Sarah G. Bonaffini   +2 more
doaj   +1 more source

Botulinum toxin a in the treatment of blepharospasm - A 10-year experience [PDF]

open access: yes, 2005
To evaluate the long-term effect of botulinum toxin type A (BTX) in the treatment of blepharospasm, a retrospective analysis was conducted from the patients seen at the Movement Disorders Clinic of the Department of Neurology, Hospital das Clinicas ...
Goncalves, LR   +7 more
core   +1 more source

First confirmed case of infant botulism in Africa, caused by a dual-toxin-producing Clostridium botulinum strain

open access: yesInternational Journal of Infectious Diseases, 2021
Botulism, a rare life-threatening toxemia, is probably underdiagnosed in all of its forms in Africa. This study reports the first laboratory-supported case of infant botulism on the African continent.
Marné N. Vosloo   +10 more
doaj   +1 more source

TITRATION OF BOTULINUM ANTITOXIN OF LOW LEVELS BY THE SCORE METHOD

open access: yesJapanese Journal of Medical Science and Biology, 1990
Botulinum antitoxin is commonly titrated by injecting a mixture of toxin and antitoxin into mice and by utilizing deaths as a marker to measure the amount of unneutralized toxin. We attempted to titrate antitoxin by converting the severity of symptoms (notably palsy) and time-to-death in days into scores.
TAKAHASHI, Motohide   +3 more
openaire   +3 more sources

Wound botulism caused by Clostridium subterminale after a heroin injection

open access: yesInfectious Disease Reports, 2018
Botulism is caused by toxin production from many species of Clostridium, most commonly Clostridium botulinum as well as C. baratii and C. butyricum. Development of wound botulism is associated with injection drug users but has also been described in ...
Paris A. Cook   +3 more
doaj   +1 more source

Adverse Drug Reaction Study of Botulinum Toxin‐A in the Real World

open access: yesJournal of Cosmetic Dermatology, Volume 25, Issue 6, June 2026.
ABSTRACT Background Despite the increasing use of botulinum toxin type A (BoNT‐A) in aesthetic and therapeutic applications, its real‐world adverse drug reaction (ADR) profile remains incompletely characterized. Current evidence relies largely on small‐scale clinical observations rather than large, systematic analyses.
Jiaxu Gu   +9 more
wiley   +1 more source

Intestinal Toxemia Botulism in 3 Adults, Ontario, Canada, 2006–2008

open access: yesEmerging Infectious Diseases, 2012
Five cases of intestinal toxemia botulism in adults were identified within an 18-month period in or near Toronto, Ontario, Canada. We describe findings for 3 of the 5 case-patients.
Yolanda D. Sheppard   +17 more
doaj   +1 more source

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