Results 31 to 40 of about 379 (143)

Wound Botulism in Black Tar Heroin Injecting Users: A Case Series

Journal of Investigative Medicine High Impact Case Reports, 2021
The incidence of wound botulism in injection drug users has increased since the introduction of black tar heroin. Many species of the Clostridium genus, most commonly Clostridium botulinum, Clostridium baratii , and Clostridium butyricum , have been ...
Nadia Raza MD, Sandhya Dhital MS, Valerie Elise Espinoza MS, Roopam Jariwal MD, Chien-Wai Chiu MD, Michael Valdez MD, Arash Heidari MD, FACP, Greti Petersen MD, FACP, Katayoun Sabetian MD   +8 more
doaj   +1 more source

Pediatric Botulism and Use of Equine Botulinum Antitoxin in Children: A Systematic Review [PDF]

Clinical Infectious Diseases, 2017
Botulism manifests with cranial nerve palsies and flaccid paralysis in children and adults. Botulism must be rapidly identified and treated; however, clinical presentation and treatment outcomes of noninfant botulism in children are not well described.We searched 12 databases for peer-reviewed and non-peer-reviewed reports with primary data on botulism
Stephanie E, Griese, Hannah M, Kisselburgh, Michael T, Bartenfeld, Erin, Thomas, Agam K, Rao, Jeremy, Sobel, Eric J, Dziuban   +6 more
openaire   +2 more sources

BOTOX injection to treat strabismus after infant botulism type B infection

American Journal of Ophthalmology Case Reports, 2020
Purpose: The significance of botulinum toxin to ophthalmologists is twofold. Botulism, a medical emergency, frequently presents with ocular findings including blurred vision, diplopia, ptosis, and photophobia as a result of the neurotoxin produced by ...
Sarah G. Bonaffini, Victoria Cocozza, Jing Jin   +2 more
doaj   +1 more source

Neurotropic Effect of Botulinum Toxin and the Potential of Specific Serum Therapy in Botulism (Review)

Безопасность и риск фармакотерапии
INTRODUCTION. The outbreak of foodborne botulism that occurred in Russia in June 2024 once again demonstrated the danger of this rather rare but severe infectious disease caused by ingesting botulinum neurotoxin.
E. M. Eliseeva, I. A. Mazerkina, A. A. Chistokhina   +2 more
doaj   +1 more source

First confirmed case of infant botulism in Africa, caused by a dual-toxin-producing Clostridium botulinum strain

International Journal of Infectious Diseases, 2021
Botulism, a rare life-threatening toxemia, is probably underdiagnosed in all of its forms in Africa. This study reports the first laboratory-supported case of infant botulism on the African continent.
Marné N. Vosloo, Christoffel J. Opperman, Hermanus D.W. Geyer, Grace M. Setshedi, Mushal Allam, Stanford Kwenda, Arshad Ismail, Zamantungwa T.H. Khumalo, Adrian J. Brink, John A. Frean, Jennifer Rossouw   +10 more
doaj   +1 more source

TITRATION OF BOTULINUM ANTITOXIN OF LOW LEVELS BY THE SCORE METHOD

Japanese Journal of Medical Science and Biology, 1990
Botulinum antitoxin is commonly titrated by injecting a mixture of toxin and antitoxin into mice and by utilizing deaths as a marker to measure the amount of unneutralized toxin. We attempted to titrate antitoxin by converting the severity of symptoms (notably palsy) and time-to-death in days into scores.
TAKAHASHI, Motohide, KOMIYA, Takako, KAMEYAMA, Shoichi, SAKAGUCHI, Genji   +3 more
openaire   +3 more sources

Adverse Drug Reaction Study of Botulinum Toxin‐A in the Real World

Journal of Cosmetic Dermatology, Volume 25, Issue 6, June 2026.
ABSTRACT Background Despite the increasing use of botulinum toxin type A (BoNT‐A) in aesthetic and therapeutic applications, its real‐world adverse drug reaction (ADR) profile remains incompletely characterized. Current evidence relies largely on small‐scale clinical observations rather than large, systematic analyses.
Jiaxu Gu, Yue Sun, Kexin Chen, Jieyi Wang, Bingcheng Lu, Hongqiang Xie, Xiaoming Liu, Cong Huang, Xingling Jian, Bo Yu   +9 more
wiley   +1 more source

Wound botulism caused by Clostridium subterminale after a heroin injection

Infectious Disease Reports, 2018
Botulism is caused by toxin production from many species of Clostridium, most commonly Clostridium botulinum as well as C. baratii and C. butyricum. Development of wound botulism is associated with injection drug users but has also been described in ...
Paris A. Cook, Aimee Mishler, Dan Quan, Ashley Parrish-Garcia   +3 more
doaj   +1 more source

Equine botulism

Equine Veterinary Journal, Volume 58, Issue 2, Page 333-347, March 2026.
Abstract Botulism is a severe and often fatal disease in equine patients worldwide. Clostridium botulinum is a ubiquitous soil organism which produces a potent neurotoxin resulting in neuromuscular blockade and flaccid paralysis in affected animals. Definitive diagnosis is often impractical or impossible, leading to diagnosis and treatment based on ...
Kali Slavik, Robert Whitlock, Amy Johnson   +2 more
wiley   +1 more source

Oral proton‐reprogrammed nanomedicine to break the inflammatory bowel disease‐Clostridium difficile infection vicious cycle

iMeta, Volume 5, Issue 1, February 2026.
Research on the mechanism of OPR restoring intestinal epithelial cell (IEC) structure and function in inflammatory bowel disease (IBD) treatment. (A) Schematic diagram of OPR structure and the rate of GP release under different conditions. (B) Schematic diagram of OPR targeting IBD colonic lesions through charge interaction.
Wensheng Chen, Yuntao Zhang, Jue Wang, Yiming Li, Hao Wu, Qiong Huang, Wei Wu, Kelong Ai   +7 more
wiley   +1 more source