Results 41 to 50 of about 2,075 (191)
A Three-Monoclonal Antibody Combination Potently Neutralizes BoNT/G Toxin in Mice
Toxins, 2023 Equine-derived antitoxin (BAT®) is the only treatment for botulism from botulinum neurotoxin serotype G (BoNT/G). BAT® is a foreign protein with potentially severe adverse effects and is not renewable.
Yongfeng Fan +9 more
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Wound Botulism Caused by Botulinum Neurotoxin Type A in a Chronic Parenteral Drug Abuser
Case Reports in Neurology, 2020 Botulism is an acute paralytic disease caused by botulinum neurotoxin (BoNT)-mediated inhibition of neurosignaling at the neuromuscular junction. BoNTs are produced by gram positive, anaerobic, spore-forming bacteria from the genus Clostridium,most ...
Sohun Awsare +2 more
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Outbreak of foodborne botulism in Alexandria, Egypt: modulating indications for administration of heptavalent botulinum antitoxin [PDF]
Environmental Science and Pollution Research, 2021 Abstract Background: In October 2019, 94 patients were admitted into Alexandria Poison Center (APC) with a history of ingestion of Feseekh (salted fish). As a trial to allocate the resources, not all patients were given Heptavalent botulinum antitoxin (HBAT) immediately.The current study aimed to portray the clinical characteristics of the ...
Sara Attia Ghitani +4 more
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Botulism outbreak in a rural Ethiopia: a case series
BMC Infectious Diseases, 2021 Background Foodborne botulism, a toxin-mediated illness caused by Clostridium botulinum, is a public health emergency. Types A, B, and E C. botulinum toxins commonly cause human disease.
Tigist Bacha +8 more
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EGYPTIAN PROTOCOL FOR MANAGEMENT OF BOTULISM
Egyptian Society of Clinical Toxicology Journal, 2019 Botulism is a muscle-paralyzing disease caused by a toxin made by a bacterium called Clostridium botulinum. Botulinum toxin binds irreversibly to presynaptic nerve endings at neuromuscular junctions.
Samah Elnagdy
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New equine antitoxins to botulinum neurotoxins serotypes A and B [PDF]
Biologicals, 2012 Hyperimmune monovalent antitoxins to botulinum neurotoxin serotypes A and B have been produced by immunizing horses with newly developed formalin toxoids. After primary immunization, horses developed acceptable prophylactic antibody titers (1-5 IU/mL). Three horses received additional toxoid booster injections to induce hyperimmune antibody titers with
D, Li, P, Mattoo, J E, Keller
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Clinical cases of atypical and severe botulism
Zaporožskij Medicinskij Žurnal, 2020 The aim of the work was to present two clinical cases of botulism: the atypical course and the severe course with late administration of heptavalent botulinum antitoxin, which still had a significant positive clinical effect and contributed to a faster ...
O. L. Ivakhiv, N. Yu. Vyshnevska
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Foodborne Botulism: Neglected Diagnosis
European Journal of Case Reports in Internal Medicine, 2019 Botulism is rare neuroparalytic disease caused by botulinum toxin, one of the most toxic substances known. Foodborne botulism is caused by consumption of foods contaminated with botulinum toxin.
Nuno Zarcos Palma +3 more
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Antitoxin reduces botulinum side effects [PDF]
Eye, 1988 Les neurotoxines de C.b., tres toxiques, agissent par inhibition de liberation d'acetylcholine, neurotransmetteur. La nature specifique de cette inhibition est discutee etl la preparation de toxine de type A purifiee specifiquement pour usage clinique est ...
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The Pan African Medical Journal, 2020 Food-borne botulism is a rare, acute and potentially fatal neurologic disorder that results from ingestion of food contaminated by botulinum toxin released from the anaerobic, spore-forming, gram-positive bacterium Clostridium botulinum.
Oyeladun Okunromade +10 more
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