Results 41 to 50 of about 379 (143)

Clinical characteristics and predictors of prolonged hospitalization in patients with cosmetic botulinum toxin poisoning: a retrospective cohort study

Frontiers in Medicine
BackgroundThe increasing cosmetic use of botulinum toxin has been accompanied by poisoning events related to inappropriate administration, including excessive dosing, unapproved or unverifiable products, self-injection, and procedures performed outside ...
Yu-quan Chen, Yi-fan Ye, Mei-wen Xie, Yu-qiang Lin, Zhi-qian Yang, Zhi Wang   +5 more
doaj   +1 more source

Chronic Botulism in Humans: A Case Series

Clinical Case Reports, Volume 13, Issue 12, December 2025.
ABSTRACT This study presents novel clinical presentations of botulism, observed in both patients and goats from the same farm. Their symptoms appeared at the same time, suggesting a possible relation to animal visceral botulism. Interestingly, weight loss and weakness were the persistent signs, but not life‐threatening as expected in botulism.
Minoosh Shabani Barzegar, Sara Pourhemmati, Masoud Mardani   +2 more
wiley   +1 more source

A cell-based alternative to the mouse potency assay for pharmaceutical type E botulinum antitoxins

ALTEX, 2021
The pharmacopeia mouse neutralization assay (PMNA) is the standard method for determining the potency of phar­maceutical botulinum antitoxins. However, a PMNA requires a large number of mice, and, thus, an alternative in vitro method to replace it is needed.
Eran, Diamant, Amram, Torgeman, Eyal, Epstein, Adva, Mechaly, Alon Ben, David, Lilach, Levin, Arieh, Schwartz, Eyal, Dor, Meni, Girshengorn, Ada, Barnea, Ohad, Mazor, Ran, Zichel   +11 more
openaire   +3 more sources

Infant Botulism: A Case Study in Integrated Clinical and Public Health Response

Clinical Case Reports, Volume 13, Issue 12, December 2025.
ABSTRACT Early recognition of constipation, feeding difficulty, and descending weakness in infants is vital for prompt diagnosis of infant botulism. Bedside nerve studies support early treatment. Rapid public health notification and coordinated access to specific therapies, including timely use of BAT and BIG‐IV, are essential to optimize outcomes and ...
John Gannon, Tiarnán Fallon Verbruggen, Sinéad Burke, Leah Loughlin, Cally Brits, Kara Tedford, John C. McHugh, Huw Mayberry, Mary O'Regan, Bridget Freyne, Niall Conroy   +10 more
wiley   +1 more source

Clostridium BotulinumTypes A and B Toxin-Antitoxin Reactions [PDF]

Journal of Hygiene, 1955
SummaryC. botulinumtypes A and B toxins required larger amounts of antitoxin for neutralization when fractions of the test dose of toxin were used than would be expected.The degree of this dilution effect, i.e. the dilution ratio, varied with different sera.
openaire   +2 more sources

Therapeutic efficacy of equine botulism heptavalent antitoxin against all seven botulinum neurotoxins in symptomatic guinea pigs

, 2019
Botulism neurotoxins are highly toxic and are potential agents for bioterrorism. The development of effective therapy is essential to counter the possible use of these toxins in military and bioterrorism scenarios, and to provide treatment in cases of ...
Shantha Kodihalli (630152), Karen T. Gillum (7392263), Nancy A. Niemuth (6612494), Douglas Barker (6199487)   +3 more
core   +1 more source

Intestinal Toxemia Botulism in 3 Adults, Ontario, Canada, 2006–2008

Emerging Infectious Diseases, 2012
Five cases of intestinal toxemia botulism in adults were identified within an 18-month period in or near Toronto, Ontario, Canada. We describe findings for 3 of the 5 case-patients.
Yolanda D. Sheppard, Dean Middleton, Yvonne Whitfield, Felix Tyndel, Shariq Haider, Jamie Spiegelman, Richard H. Swartz, Mark P. Nelder, Stacey L. Baker, Lisa Landry, Ross MacEachern, Sherri Deamond, Lorrie Ross, Garth Peters, Michelle Baird, David Rose, Greg Sanders, John W. Austin   +17 more
doaj   +1 more source

Type C botulism outbreak in free-ranging waterfowl in Goiás

Pesquisa Veterinária Brasileira, 2022
: Botulism is generally a fatal disease caused by ingestion of neurotoxins produced by Clostridium botulinum. The present study describes the epidemiological, clinical, and laboratory aspects of a type C botulism outbreak in free-living aquatic birds ...
Andressa S. Martins, Tamires A. Silva, Isabella C.C.R. Rosa, Alexia G.F. Oliveira, Márcio P. Oliveira, Júlia R. Saraiva, Iveraldo S. Dutra, Ana Carolina Borsanelli   +7 more
doaj   +1 more source

Comparative Genomics and Virulence Mechanisms to Identify Genes Related to Mucin O‐Glycan Degradation and Pathogenicity in a Potentially Multidrug‐Resistant Clostridium tertium Strain

MicrobiologyOpen, Volume 14, Issue 6, December 2025.
The comparative genomic analysis provides information about how C. tertium HGMC01 strain cause disease through mucin glycan degradation, colonization, multidrug resistance, and modulation of immune responses. Moreover, this analysis data suggest that this strain interacts with host cells by degrading mucin in the gut, potentially through recognition or
Seonghun Kim, Ji Young Kang, Jung‐Sook Lee   +2 more
wiley   +1 more source

When BAT Precedes BIG‐IV in Infant Botulism: The Need for Structured Antitoxin Decision‐Pathway Reporting in Case Reports

Clinical Case Reports
In infant botulism, use of equine‐derived botulinum antitoxin before BIG‐IV may be clinically justified when the infant‐specific product is delayed.
Muhammad Abdullah Awan, Hammad‐ud‐din Raza   +1 more
doaj   +1 more source