Familial Cluster of Foodborne Botulism Associated with Homemade Dairy Products: A Case Series [PDF]
International Medical Case Reports JournalKhadijeh Saravani,1 Amirhosein Kamrava,2 Javad Poursamimi3 1Department of Forensic Medicine and Toxicology, Zabol University of Medical Science, Zabol, Iran; 2Student Research Committee, Zabol University of Medical Sciences, Zabol, Iran; 3Department of ...
Saravani K, Kamrava A, Poursamimi J
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Infant botulism in Australia: availability of human botulinum antitoxin for treatment
Medical Journal of Australia, 2010 We report the first Australian case of treatment of infant botulism with a human botulinum antitoxin developed in the United States by the California Department of Public Health. Our patient's clinical improvement was rapid, and although the product is expensive, cost-analysis supports the economical viability of its use.
May, M. L. A. +2 more
openaire +5 more sources
Botulinum neurotoxin: from molecular pathogenesis to emerging countermeasures [PDF]
Saudi Pharmaceutical JournalBotulism is a severe neuroparalytic syndrome caused by botulinum neurotoxins (BoNTs)—among the most potent biological agents—with an estimated human lethal dose (LD50) of approximately 1 ng/kg.
Sultan Almudimeegh
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Disease Models & Mechanisms, 2018 Botulinum neurotoxin (BoNT) serotypes A, B and E are responsible for most cases of human botulism. The only approved therapy for botulism is antitoxin treatment administered to patients after symptom onset.
Amram Torgeman +11 more
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Production of monoclonal antibodies against botulinum neurotoxin in Nicotiana benthamiana
Human Vaccines & ImmunotherapeuticsBotulism is a fatal neurologic disease caused by the botulinum toxin (BoNT) produced by Clostridium botulinum. It is a rare but highly toxic disease with symptoms, such as cramps, nausea, vomiting, diarrhea, dysphagia, respiratory failure, muscle ...
Kornchanok Sangprasat +6 more
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Co-Expression and Co-Purification Enable Manufacturing of a Six-Monoclonal Antibody Botulinum Antitoxin Cocktail [PDF]
ToxinsRyan R Davis +2 more
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Chronic Botulism in Humans: A Case Series. [PDF]
Clin Case RepABSTRACT This study presents novel clinical presentations of botulism, observed in both patients and goats from the same farm. Their symptoms appeared at the same time, suggesting a possible relation to animal visceral botulism. Interestingly, weight loss and weakness were the persistent signs, but not life‐threatening as expected in botulism.
Barzegar MS, Pourhemmati S, Mardani M.
europepmc +2 more sources
Diagnosis and treatment of botulism after botulinum toxin type A injections: report of 9 cases
Di-san junyi daxue xuebao, 2021 Objective To explore the diagnostic criteria of botulism after botulinum toxin type A (BT/A) injection and observe the therapeutic effect of botulinum antitoxin.
HE Ping +5 more
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Infant Botulism: A Case Study in Integrated Clinical and Public Health Response. [PDF]
Clin Case RepABSTRACT Early recognition of constipation, feeding difficulty, and descending weakness in infants is vital for prompt diagnosis of infant botulism. Bedside nerve studies support early treatment. Rapid public health notification and coordinated access to specific therapies, including timely use of BAT and BIG‐IV, are essential to optimize outcomes and ...
Gannon J +10 more
europepmc +2 more sources
Clostridium botulinum – like organism bacteremia in a user of black tar heroin
IDCases, 2021 Wound botulism due to introduction of the anaerobic bacteria, Clostridium botulinum, into otherwise sterile, relatively anaerobic tissue is a known complication of black tar heroin use.
Therese Battiola +4 more
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