Results 21 to 30 of about 2,075 (191)

Chronic Botulism in Humans: A Case Series. [PDF]

Clin Case Rep
ABSTRACT This study presents novel clinical presentations of botulism, observed in both patients and goats from the same farm. Their symptoms appeared at the same time, suggesting a possible relation to animal visceral botulism. Interestingly, weight loss and weakness were the persistent signs, but not life‐threatening as expected in botulism.
Barzegar MS, Pourhemmati S, Mardani M.
europepmc   +2 more sources

Neutralization of Tetanus Neurotoxin with Various Botulinum Antitoxins (A-F) in a Study to Isolate Clostridium botulinum from Field Samples [PDF]

Journal of Animal and Veterinary Advances, 2010
In a study to isolate Clostridium botulinum from field samples, 53 C. botulinum-like isolates were found neutralizable by botulinum antitoxins using the standard mouse bioassay. The neutralization results of 14 of them were found false-positive due to contamination with C.
Saeed, E. M. A., Bohnel, H., Gessler, Frank   +2 more
core   +6 more sources

A Case of Botulism Fast Adjusting with Antitoxin Administration in the Early Period and the Use of Electromyography in Diagnosis [PDF]

Journal of Pediatric Emergency and Intensive Care Medicine, 2021
Botulism is a rare but potentially life-threatening neuroparalytic syndrome caused by the action of a neurotoxin caused by the bacterium Clostridium botulinum. Early diagnosis and early treatment is important. In cases where botulism occurs sporadically,
Edin Botan, Serhan Özcan, Merve Havan, Emrah Gün, Merve Feyza Yüksel, Serdar Balsak, Özge Güzelmansur, Ömer Bektaş, Tanıl Kendirli   +8 more
doaj   +2 more sources

Infant Botulism: A Case Study in Integrated Clinical and Public Health Response. [PDF]

Clin Case Rep
ABSTRACT Early recognition of constipation, feeding difficulty, and descending weakness in infants is vital for prompt diagnosis of infant botulism. Bedside nerve studies support early treatment. Rapid public health notification and coordinated access to specific therapies, including timely use of BAT and BIG‐IV, are essential to optimize outcomes and ...
Gannon J, Fallon Verbruggen T, Burke S, Loughlin L, Brits C, Tedford K, McHugh JC, Mayberry H, O'Regan M, Freyne B, Conroy N.   +10 more
europepmc   +2 more sources

Equine botulism. [PDF]

Equine Vet J
Abstract Botulism is a severe and often fatal disease in equine patients worldwide. Clostridium botulinum is a ubiquitous soil organism which produces a potent neurotoxin resulting in neuromuscular blockade and flaccid paralysis in affected animals. Definitive diagnosis is often impractical or impossible, leading to diagnosis and treatment based on ...
Slavik K, Whitlock R, Johnson A.
europepmc   +2 more sources

Familial Cluster of Foodborne Botulism Associated with Homemade Dairy Products: A Case Series [PDF]

International Medical Case Reports Journal
Khadijeh Saravani,1 Amirhosein Kamrava,2 Javad Poursamimi3 1Department of Forensic Medicine and Toxicology, Zabol University of Medical Science, Zabol, Iran; 2Student Research Committee, Zabol University of Medical Sciences, Zabol, Iran; 3Department of ...
Saravani K, Kamrava A, Poursamimi J
doaj   +2 more sources

Studying the differential efficacy of postsymptom antitoxin treatment in type A versus type B botulism using a rabbit spirometry model [PDF]

Disease Models & Mechanisms, 2018
Botulinum neurotoxin (BoNT) serotypes A, B and E are responsible for most cases of human botulism. The only approved therapy for botulism is antitoxin treatment administered to patients after symptom onset.
Amram Torgeman, Arieh Schwartz, Eran Diamant, Tzadok Baruchi, Eyal Dor, Alon Ben David, Avi Pass, Ada Barnea, Arnon Tal, Amir Rosner, Osnat Rosen, Ran Zichel   +11 more
doaj   +2 more sources

Botulinum neurotoxin: from molecular pathogenesis to emerging countermeasures [PDF]

Saudi Pharmaceutical Journal
Botulism is a severe neuroparalytic syndrome caused by botulinum neurotoxins (BoNTs)—among the most potent biological agents—with an estimated human lethal dose (LD50) of approximately 1 ng/kg.
Sultan Almudimeegh
doaj   +2 more sources

Use of Botulism Antitoxin Heptavalent (A, B, C, D, E, F, G)—(Equine) (BAT^®) in Clinical Study Subjects and Patients: A 15-Year Systematic Safety Review [PDF]

Toxins, 2021
Botulism is a rare, sometimes fatal paralytic illness caused by botulinum neurotoxins. BAT® (Botulism Antitoxin Heptavalent (A, B, C, D, E, F, G)—(Equine)) is an equine-derived heptavalent botulinum antitoxin indicated for the treatment of symptomatic ...
Geraldine S. Parrera, Hugo Astacio, Priya Tunga, Deborah M. Anderson, Christine L. Hall, Jason S. Richardson   +5 more
doaj   +2 more sources

Iatrogenic Botulism After Cosmetic Use of Botulinum Toxin-A: A Case Series. [PDF]

Clin Case Rep
ABSTRACT Botulism symptoms after cosmetic botulinum toxin‐A (BTX‐A) injections happen very rarely, and it needs careful attention since it can be life‐threatening. Hence, it is advised to meticulously check the technique, dose, and authenticity of the BTX‐A before injections to reduce the adverse effects.
Asadi M, Shadnia S, Mostafazadeh B, Evini PET, Zandieh F, Rahimi M.   +5 more
europepmc   +2 more sources