Immunological Characterization and Neutralizing Ability of Monoclonal Antibodies Directed Against Botulinum Neurotoxin Type H. [PDF]
, 2016 BackgroundOnly Clostridium botulinum strain IBCA10-7060 produces the recently described novel botulinum neurotoxin type H (BoNT/H). BoNT/H (N-terminal two-thirds most homologous to BoNT/F and C-terminal one-third most homologous to BoNT/A) requires ...
Arnon, Stephen S +5 more
core +1 more source
Conjugative botulinum neurotoxin-encoding plasmids in Clostridium botulinum. [PDF]
PLoS ONE, 2010 Clostridium botulinum produces seven distinct serotypes of botulinum neurotoxins (BoNTs). The genes encoding different subtype neurotoxins of serotypes A, B, F and several dual neurotoxin-producing strains have been shown to reside on plasmids ...
Kristin M Marshall +2 more
doaj +1 more source
Cost minimization analysis of BoNT-As in the treatment of upper limb spasticity and cervical dystonia [PDF]
, 2016 Botulinum toxin type A (BoNT-A) injections are recommended for the management of upper limb spasticity (ULS) and cervical dystonia (CD). The main aim of this cost minimization analysis (CMA) was to compare the annual cost per patient for three BoNT-As ...
Bartolomei, Luigi +15 more
core +1 more source
A pragmatic harm reduction approach to manage a large outbreak of wound botulism in people who inject drugs, Scotland 2015 [PDF]
, 2018 Background People who inject drugs (PWID) are at an increased risk of wound botulism, a potentially fatal acute paralytic illness. During the first 6 months of 2015, a large outbreak of wound botulism was confirmed among PWID in Scotland, which resulted ...
Amanda Weir +43 more
core +1 more source
Antipruritic Effects of Botulinum Neurotoxins [PDF]
Toxins, 2018 This review explores current evidence to demonstrate that botulinum neurotoxins (BoNTs) exert antipruritic effects. Both experimental and clinical conditions in which botulinum neurotoxins have been applied for pruritus relief will be presented and significant findings will be highlighted.
openaire +5 more sources
An Integrative Approach to Computational Modelling of the Gene Regulatory Network Controlling Clostridium botulinum Type A1 Toxin Production [PDF]
, 2016 Clostridium botulinum produces botulinum neurotoxins (BoNTs), highly potent substances responsible for botulism. Currently, mathematical models of C.
Barker, Gary C. +4 more
core +2 more sources
Central Effects of Botulinum Neurotoxin—Evidence from Human Studies
Toxins, 2019 For more than three decades, Botulinum neurotoxin (BoNT) has been used to treat a variety of clinical conditions such as spastic or dystonic disorders by inducing a temporary paralysis of the injected muscle as the desired clinical effect.
D. Weise, C. Weise, M. Naumann
semanticscholar +1 more source
Use of Botulinum Neurotoxin in Ophthalmology
Türk Oftalmoloji Dergisi, 2016 Botulinum neurotoxin (BoNT) is the first biological toxin used in the treatment of ophthalmic diseases and to decrease skin wrinkles as an aesthetic agent. When used appropriately, it weakens the force of muscular contraction and/or inhibits glandular secretion.
Ceyhun Arici, Emel Başar
openaire +4 more sources
PLoS ONE, 2013 Sanger and shotgun sequencing of Clostridium botulinum strain Af84 type Af and its botulinum neurotoxin gene (bont) clusters identified the presence of three bont gene clusters rather than the expected two. The three toxin gene clusters consisted of bont
Nir Dover +6 more
doaj +1 more source
Toxins, 2021 Breast reconstruction after mastectomy is commonly performed using transverse rectus abdominis myocutaneous (TRAM) flap. Previous studies have demonstrated that botulinum neurotoxin injections in TRAM flap surgeries lower the risk of necrosis and allow ...
Kyu-Ho Yi +4 more
doaj +1 more source