Results 71 to 80 of about 83,600 (312)
Identification of a novel botulinum neurotoxin gene cluster in Enterococcus
FEBS Letters, 2018 The deadly neurotoxins of Clostridium botulinum (BoNTs) comprise eight serotypes (A–G; X). The neurotoxin gene cluster encoding BoNT and its accessory proteins includes an operon containing an ntnh gene upstream of the boNT gene.
J. Brunt +3 more
semanticscholar +1 more source
Botulinum neurotoxins: Future innovations
Medicine, 2023 Botulinum neurotoxins (BoNTs) are multi-domain proteins whose potent and selective actions on nerve endings have led to innovations in both basic and clinical science. The various BoNT domains are responsible for binding to gangliosides and proteins associated with nerve cell membranes, internalization into the cell, and cleavage of one or more SNARE (
Brideau-Andersen, Amy +2 more
openaire +2 more sources
Developmental Medicine & Child Neurology, 2019 To examine changes in objective and subjective drooling severity measures after submandibular botulinum neurotoxin A injection in children with neurodevelopmental disabilities, explore their relationship, and evaluate if clinically relevant responses ...
K. van Hulst +4 more
semanticscholar +1 more source
Challenging the Clostridium botulinum toxin type A (BoNT/A) with a selection of microorganisms by culture methods and extended storage of used vials to assess the loss of sterility [PDF]
, 2015 In 2002, botulinum toxin type A (BoNT/A) was approved by the US Food and Drug Administration (FDA) for cosmetic use. However, there may be procedural differences between the ways in which a clinician handles, applies and stores the product compared to ...
Crean, Stjohn +4 more
core
Botulinum neurotoxin type C protease induces apoptosis in differentiated human neuroblastoma cells [PDF]
, 2016 Neuroblastomas constitute a major cause of cancer-related deaths in young children. In recent years, a number of translation-inhibiting enzymes have been evaluated for killing neuroblastoma cells. Here we investigated the potential vulnerability of human
Binz, T. +3 more
core +1 more source
The Scientific World JournalThis paper explores the role of botulinum neurotoxin in aiding fracture recovery through temporary muscle paralysis. Specifically, it investigates the effects of botulinum neurotoxin-induced paralysis of the sternocleidomastoid muscle on clavicle ...
Themistoklis Vampertzis +6 more
doaj +1 more source
Health‐Related Quality of Life in Relation to the 5‐2‐1 Criteria in Parkinson's Disease in Sweden
Movement Disorders Clinical Practice, EarlyView.Abstract Background Device‐aided therapies (DAT) offer alternatives to oral or transdermal dopaminergic treatments in advanced Parkinson's disease (PD), where they can reduce motor fluctuations and dyskinesia and improve health‐related quality of life (HRQoL).
Frida Hjalte +5 more
wiley +1 more source
Botulinum neurotoxin formulations: overcoming the confusion
Clinical, Cosmetic and Investigational Dermatology, 2018 Botulinum toxin A is produced by anaerobic spore-forming bacteria and is used for various therapeutic and cosmetic purposes. Botulinum toxin A injections are the most popular nonsurgical procedure worldwide.
Souphiyeh Samizadeh, K. De Boulle
semanticscholar +1 more source
The usage of botulinum in the treatment of masticatory muscles hyperactivity
Journal of Education, Health and Sport, 2022 Introduction and purpose: Masticatory muscles hyperactivity is currently a very common problem among adult population. The ignorance of the symptoms and the lack or unsuccessful treatment may lead to serious health complications, which lead to major ...
Martyna Drożak +2 more
doaj +1 more source
Developmental Medicine & Child Neurology, 2018 This study aimed to track alterations in muscle volume for 6 months in children with cerebral palsy (CP) after the first exposure to botulinum neurotoxin A (BoNT‐A), a commonly used focal spasticity treatment.
C. Alexander +7 more
semanticscholar +1 more source