Results 81 to 90 of about 83,600 (312)

Cluster of Botulism among dutch tourists in Turkey, june 2008 [PDF]

, 2010
In June 2008, three Dutch tourists participating in a mini-cruise in Turkey needed urgent repatriation for antitoxin treatment because of symptoms of botulism.
Ouwerkerk, M., van, Roest, H.I.J., Swaan, C.M.   +2 more
core   +1 more source

Patient-Reported Side Effects of Intradetrusor Botulinum Toxin Type A for Idiopathic Overactive Bladder Syndrome [PDF]

, 2011
Objective: The aim of the study was a prospective assessment of patient-reported side effects in an open-label study after intradetrusor botulinum toxin injections for idiopathic overactive bladder (OAB). Patients and Methods: Botulinum toxin A injection
Alexander Buchner, Alexander Roosen, Andersson KE, Chancellor MB, Christian G. Stief, Christian Gratzke, Cohen BL, Coyne KS, Eleopra R, Florian May, Garner CG, Jeffery S, Kalsi V, Lange DJ, Margit E. Mayer, Mehnert U, Mohanty NK, Ricarda M. Bauer, Shaban AM, Smith CP, Yasmin Hocaoglu   +20 more
core   +1 more source

Systemic adverse events after botulinum neurotoxin A injections in children with cerebral palsy

Developmental Medicine & Child Neurology, 2018
To identify factors that increase the likelihood of systemic adverse events after botulinum neurotoxin A (BoNT‐A) injections in children with cerebral palsy (CP).
S. Paget, Caitlyn M Swinney, Karen L. O. Burton, Karen Bau, S. O'Flaherty   +4 more
semanticscholar   +1 more source

Independent evolution of neurotoxin and flagellar genetic loci in proteolytic Clostridium botulinum

BMC Genomics, 2009
Background Proteolytic Clostridium botulinum is the causative agent of botulism, a severe neuroparalytic illness. Given the severity of botulism, surprisingly little is known of the population structure, biology, phylogeny or evolution of C.
Twine Susan M, Mason David R, Paul Catherine J, Carter Andrew T, Alston Mark J, Logan Susan M, Austin John W, Peck Michael W   +7 more
doaj   +1 more source

Exploring the functional domain and the target of the tetanus toxin light chain in neurohypophysial terminals [PDF]

, 1994
The tetanus toxin light chain blocks calcium induced vasopressin release from neurohypophysial nerve terminals. Here we show that histidine residue 233 within the putative zinc binding motif of the tetanus toxin light chain is essential for the ...
Binz, T., Dayanithi, G., Gratzl, Manfred, Höhne-Zell, B., Niemann, H., Stecher, B., Weller, U., Yamasaki, S.   +7 more
core   +1 more source

Transynaptic Action of Botulinum Neurotoxin Type A at Central Cholinergic Boutons

Journal of Neuroscience, 2018
Botulinum neurotoxin Type A (BoNT/A) is an effective treatment for several movement disorders, including spasticity and dystonia. BoNT/A acts by cleaving synaptosomal-associated protein of 25 kDa (SNAP-25) at the neuromuscular junction, thus blocking ...
M. Caleo, M. Spinelli, Francesca Colosimo, I. Matak, O. Rossetto, Z. Lacković, L. Restani   +6 more
semanticscholar   +1 more source

Applications, impacts and consequences of botulinum toxin usage in medicine

Journal of Education, Health and Sport
Introduction Botulinum toxin is a neurotoxin produced by the gram-positive bacteria Clostridium botulinum. Botulinum toxin has found great interest in the field of aesthetic medicine, but it has many other applications in other areas of medicine.  
Weronika Kiełt, Julia Kozłowska, Gabriela Broniec, Barbara Wajdowicz, Aleksandra Kudła, Rozalia Czapiewska, Aleksandra Dziewulska, Aleksandra Wróbel, Laura Pacek, Klaudia Kowalska   +9 more
doaj   +1 more source

The Mild Behavioral Impairment Checklist for Parkinson's Disease: An Ancillary Instrument in Cognitive Assessment

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Mild behavioral impairment (MBI) is a syndrome characterized by the later‐life onset of neuropsychiatric symptoms (NPS) and serves as a potential marker for dementia. In Parkinson's disease (PD), MBI has been associated with worse cognition, cortical atrophy, and altered connectivity.
Gabriel D. Pinilla‐Monsalve, Yuan P. Song, Alexandru Hanganu, Zahinoor Ismail, Oury Monchi   +4 more
wiley   +1 more source

Medial gastrocnemius volume and echo‐intensity after botulinum neurotoxin A interventions in children with spastic cerebral palsy

Developmental Medicine & Child Neurology, 2018
This cross‐sectional investigation evaluated whether recurrent botulinum neurotoxin A (BoNT‐A) interventions to the medial gastrocnemius have an influence on muscle morphology, beyond Gross Motor Function Classification System (GMFCS) level.
S. Schless, F. Cenni, L. Bar-On, B. Hanssen, B. Kalkman, T. O'Brien, E. Aertbeliën, A. Van Campenhout, G. Molenaers, K. Desloovere   +9 more
semanticscholar   +1 more source

Rapid Detection of Botulinum Neurotoxins—A Review [PDF]

Toxins, 2019
A toxin is a poisonous substance produced within living cells or organisms. One of the most potent groups of toxins currently known are the Botulinum Neurotoxins (BoNTs). These are so deadly that as little as 62 ng could kill an average human; to put this into context that is approximately 200,000 × less than the weight of a grain of sand.
Robert J. Hobbs, Carol A. Thomas, Jennifer Halliwell, Christopher D. Gwenin   +3 more
openaire   +4 more sources