Autoimmunity to Collagen XVII (BP180-Ag2) in Pemphigoid Associated With Parkinson’s Disease [PDF]
The association between Parkinson’s disease and autoimmune disease is rare; in our population, there is 1 case per 10,000 inhabitants. Bullous pemphigoid has a much lower incidence, and consequently, the association of Parkinson’s disease and bullous ...
Ricardo Cid-Puente +5 more
doaj +3 more sources
Anti-BP180 Autoantibodies Are Present in Stroke and Recognize Human Cutaneous BP180 and BP180-NC16A [PDF]
Objective: Current evidence has revealed a significant association between bullous pemphigoid (BP) and neurological diseases (ND), including stroke, but the incidence of BP autoantibodies in patients with stroke has not previously been investigated.
Yanan Wang +8 more
doaj +3 more sources
BP180 Is Critical in the Autoimmunity of Bullous Pemphigoid [PDF]
Bullous pemphigoid (BP) is by far the most common autoimmune blistering dermatosis that mainly occurs in the elderly. The BP180 is a transmembrane glycoprotein, which is highly immunodominant in BP. The structure and location of BP180 indicate that it is
Yale Liu, Liang Li, Yumin Xia
doaj +3 more sources
Analysis of the autoimmune response to BP180 in Chinese stroke patients [PDF]
Background Significant association between bullous pemphigoid (BP) and stroke has been reported. This study aimed to evaluate the level of anti-BP180 antibody in stroke patients to explore the relationship between BP and stroke in their pathogenesis ...
Jing Wang +4 more
doaj +3 more sources
The significance of preclinical anti-BP180 autoantibodies
Bullous pemphigoid (BP) is the most common autoimmune subepidermal blistering disease. Although the pathomechanism of BP onset has yet to be elucidated in detail, BP autoantibodies targeting two hemidesmosomal components, BP180 and BP230, are known to ...
Yosuke Mai +3 more
doaj +3 more sources
Evaluation of a novel chemiluminescent immunoassay for autoantibody detection in pemphigus and bullous pemphigoid [PDF]
BackgroundA novel fully automated chemiluminescent immunoassay (CLIA) has been developed to quantify autoantibodies specific for desmogleins (Dsg1, Dsg3), BP180, and BP230, key target antigens in pemphigus and bullous pemphigoid.
Na Zhang +14 more
doaj +2 more sources
Serum levels of interleukin-17, -18, -22, and -25 in patients with bullous pemphigoid before and after treatment [PDF]
ObjectiveThis study aimed to explore the relationship between serum levels of interleukin-17 (IL-17), interleukin-18 (IL-18), interleukin-22 (IL-22), interleukin-25 (IL-25), anti-BP180 antibodies, anti-BP230 antibodies, and immunoglobulin E (IgE) and the
Xinyi Hong +23 more
doaj +2 more sources
Home‐based collaborative management of bullous pemphigoid with delayed seropositive conversion of anti‐BP180‐NC16a antibody [PDF]
We report the case of an 82‐year‐old male with a history of multiple cerebral infarctions who developed bullous pemphigoid while receiving home‐based care.
Hiromitsu Yamashita +3 more
doaj +2 more sources
BP180/Collagen XVII: A Molecular View [PDF]
BP180 is a type II collagenous transmembrane protein and is best known as the major autoantigen in the blistering skin disease bullous pemphigoid (BP). The BP180 trimer is a central component in type I hemidesmosomes (HD), which cause the adhesion between epidermal keratinocytes and the basal lamina, but BP180 is also expressed in several non-HD ...
Tasanen-Määttä Kaisa +2 more
openaire +3 more sources
Current approaches to the diagnosis of autoimmune bullous dermatoses
A modern review of highly effective methods for the diagnosis of autoimmune bullous dermatoses are presented. The specificity of the production of autoantibodies underlying bullous dermatoses are described.
Marianna B. Drozhdina +2 more
doaj +1 more source

