Results 31 to 40 of about 4,291 (203)
Deciphering the Contribution of BP230 Autoantibodies in Bullous Pemphigoid
Antibodies, 2022 Bullous pemphigoid (BP) is a subepidermal autoimmune blistering disease predominantly affecting elderly patients and carries significant morbidity and mortality.
Connor Cole +2 more
doaj +1 more source
Bullous pemphigoid in infants: characteristics, diagnosis and treatment [PDF]
, 2014 BACKGROUND: Bullous pemphigoid (BP) in infants is a rare but increasingly reported autoimmune blistering skin disease. Autoantibody reactivity is usually poorly characterized. Current guidelines do not address specific aspects of the infantile form of BP.
Agnes Schwieger-Briel +8 more
core +2 more sources
Immunological Medicine, 2019 Bullous pemphigoid (BP) is an organ-specific autoantibody-mediated autoimmune blistering skin disorder that tends to affect the elderly. Tense blister formation associated with itchy urticarial erythema is clinically observed in BP, and subepidermal ...
Wataru Nishie
doaj +1 more source
Human eosinophils express the high affinity IgE receptor, FcεRI, in bullous pemphigoid.
PLoS ONE, 2014 Bullous pemphigoid (BP) is an autoimmune blistering disease mediated by autoantibodies targeting BP180 (type XVII collagen). Patient sera and tissues typically have IgG and IgE autoantibodies and elevated eosinophil numbers. Although the pathogenicity of
Kelly N Messingham +5 more
doaj +1 more source
Significant Role of Collagen XVII And Integrin beta 4 in Migration and Invasion of The Less Aggressive Squamous Cell Carcinoma Cells [PDF]
, 2017 Collagen XVII and integrin alpha 6 beta 4 have well-established roles as epithelial adhesion molecules. Their binding partner laminin 332 as well as integrin alpha 6 beta 4 are largely recognized to promote invasion and metastasis in various cancers, and
Franzke, Claus-Werner +13 more
core +9 more sources
Molecular architecture and function of the hemidesmosome [PDF]
, 2015 Hemidesmosomes are multiprotein complexes that facilitate the stable adhesion of basal epithelial cells to the underlying basement membrane. The mechanical stability of hemidesmosomes relies on multiple interactions of a few protein components that form ...
Gerhard Wiche +2 more
core +3 more sources
Frontiers in Immunology, 2023 Linear IgA/IgG bullous dermatosis (LAGBD) is a rare autoimmune subepidermal bullous disorder characterized by linear deposition of concurrent IgA and IgG autoantibodies along the basement membrane zone (BMZ). The clinical features of LAGBD can be diverse,
Yuxi Zhou +7 more
doaj +1 more source
Are Anti-BP180 IgG1 or IgG4 Autoantibodies Pathogenic? [PDF]
Journal of Investigative Dermatology, 2002 Bullous pemphigoid (BP) is an acquired autoimmune skin disease characterized by autoantibodies against two hemidesmosomal antigens, BP230 (BPAG1) and BP180 (BPAG2) and subepidermal blisters (Stanley et al, 1981; Diaz et al, 1990; Stanley, 1999). In the skin lesions of these patients basal keratinocytes detach from the underlying dermis at the level of ...
openaire +2 more sources
Case Report: The many faces of bullous pemphigoid
Frontiers in Immunology, 2023 The pemphigoid group comprises a number of bullous skin diseases with autoantibodies against different constituents of the basement membrane zone that result in subepidermal detachment and clinically characteristic tense blisters, erosions, urticarial ...
Laura Rechtien +9 more
doaj +1 more source
Mixed muco-cutaneous pemphigoid: Clinical and immunological features of 15 cases
Frontiers in Immunology, 2023 IntroductionWe describe a series of patients whose auto-immune bullous skin disease (AIBD) of the dermal-epidermal junction (DEJ) was characterized by clinical, immunological and ultrastructural features intermediate between bullous pemphigoid (BP) and ...
Raphaël Janela +9 more
doaj +1 more source