Results 31 to 40 of about 567,455 (203)
Bradykinin receptors in GtoPdb v.2023.1 [PDF]
, 2023 Bradykinin (or kinin) receptors (nomenclature as agreed by the NC-IUPHAR subcommittee on Bradykinin (kinin) Receptors [92]) are activated by the endogenous peptides bradykinin (BK), [des-Arg9]bradykinin, Lys-BK (kallidin), [des-Arg10]kallidin, [Phospho ...
Faussner, Alexander +17 more
core +1 more source
Guanosine nucleotides regulate B2 kinin receptor affinity of agonists but not of antagonists: Discussion of a model proposing receptor precoupling to G protein [PDF]
, 2000 The effect of nucleotides on binding of the B2 kinin (BK) receptor agonist {[}H-3]BK and the antagonist {[}H-3]NPC17731 to particulate fractions of human foreskin fibroblasts was studied.
Er Faussner +3 more
core +1 more source
In Vitro Pharmacological Profile of a New Small Molecule Bradykinin B2 Receptor Antagonist
Frontiers in Pharmacology, 2020 We here report the discovery and early characterization of Compound 3, a representative of a novel class of small molecule bradykinin (BK) B2 receptor antagonists, and its superior profile to the prior art B2 receptor antagonists Compound 1 and Compound ...
Anne Lesage +8 more
doaj +1 more source
Die Funktion der Helix 8 für die Regulation des Bradykinin B2 Rezeptors [PDF]
, 2012 Upon activation the human bradykinin B2 receptor (B2R) acts as guanine nucleotide exchange factor for the G proteins Gq/11 and Gi. Thereafter, it gets phosphorylated by G protein-coupled receptor kinases (GRKs) and recruits beta-arrestins, which block ...
Feierler, Jens
core +1 more source
Degradation of human kininogens with the release of kinin peptides by extracellular proteinases of Candida spp. [PDF]
, 2010 The secretion of proteolytic enzymes by pathogenic microorganisms is one of the most successful strategies used by pathogens to colonize and infect the host organism.
Andrzej Kozik +16 more
core +2 more sources
, 1994 1. Dynamic video imaging was used to measure the des-Arg9-bradykinin-induced changes in the intracellular free calcium ion concentration ([Ca2+]i) of single bovine tracheal smooth muscle (BTSM) cells. 2. In the presence of extracellular calcium ions, des-
Katrina Firth (17157820) +1 more
core +5 more sources
Bradykinin is a mediator of anaphylactoid reactions during hemodialysis with AN69 membranes [PDF]
, 1994 Bradykinin is a mediator of anaphylactoid reactions during hemodialysis with AN69 membranes. Anaphylactoid reactions (AR) are the most feared complications of hemodialysis.
Verresen, Luc +7 more
core +1 more source
International Journal of Cardiology: Heart & Vasculature, 2018 Background: Physiological pathways such as bradykinin, renin-angiotensin, neurohormones and nitric oxide have been shown to play an important role in the regulation of cardiovascular function.
Rafael Amorim Belo Nunes +5 more
doaj +1 more source
Brazilian Journal of Medical and Biological Research, 1998 The most conspicuous effect of bradykinin following its administration into the systemic circulation is a transient hypotension due to vasodilation.
A.C. Resende, G. Ballejo, M.C.O. Salgado
doaj +1 more source
Roles of Kinins in the Nervous System
Cell Transplantation, 2015 The kallikrein-kinin system (KKS) is an endogenous pathway involved in many biological processes. Although primarily related to blood pressure control and inflammation, its activation goes beyond these effects.
Priscilla D. Negraes +4 more
doaj +1 more source