Results 51 to 60 of about 21,207 (157)

Induction of bradykinin B1 receptor in rats

Folia Pharmacologica Japonica, 1997
We found the time-dependent induction of the systemic hypotensive response to des-Arg9-bradykinin and the contractile response of ileum of rats to des-Arg9-bradykinin. Both induced responses to des-Arg9-bradykinin were inhibited by treatment with a B1 receptor competitive antagonist, while the responses to bradykinin was constant throughout the ...
UENO, Akinori, OH-ISHI, Sachiko
openaire   +2 more sources

Contact System Activation in Plasma from Dengue Patients Might Harness Endothelial Virus Replication through the Signaling of Bradykinin Receptors. [PDF]

Pharmaceuticals (Basel), 2021
Coelho SVA, Rust NM, Vellasco L, Papa MP, Pereira ASG, Silva Palazzo MFD, Juliano MA, Costa SM, Alves AMB, Cordeiro MT, Marques ETA, Scharfstein J, Arruda LB.   +12 more
europepmc   +1 more source

A novel anti-thrombotic mechanism mediated by the receptors of the kallikrein/kinin and renin-angiotensin systems

Frontiers in Medicine, 2016
The contact activation (CAS) and kallikrein/kinin (KKS) systems regulate thrombosis risk two ways. First, the CAS influences contact activation-induced factor XI activation and thrombin formation through the hemostatic cascade.
Alvin H. Schmaier
doaj   +1 more source

The kallikrein-Kinin system modulates the progression of colorectal liver metastases in a mouse model

BMC Cancer, 2018
Background The Kallikrein-Kinin System (KKS) has been found to play a role in tumor progression in several cancers. The KKS metabolic cascade depends on signalling through two cross talking receptors; bradykinin receptor 1 (B1R) and bradykinin receptor 2
Patricia Luiza Nunes da Costa, David Wynne, Theodora Fifis, Linh Nguyen, Marcos Perini, Christopher Christophi   +5 more
doaj   +1 more source

THE CORONARY VASCULATURE AND THE MYOCARDIUM

Journal of Biological Research, 1999
It has been reported that the activity of bradykinin on vascular endothelial receptors results in vasodilatation ( 1-3) due to the release of both nitric oxide (NO) and the so called endothelial-derived hyperpolarizing factor (EDHF) (4-7).
F. Ceresa, A. Delfino, A. De Matteis, N. Ferrero, M. Novarino, A. Rittà   +5 more
doaj  

An uncommon case of postpartum venous thrombosis in a patient with hereditary angioedema. Patient from the ITACA Cohort (Italian Network for Hereditary and Acquired Angioedema)

Italian Journal of Medicine
Hereditary angioedema (HAE) is a rare genetic condition characterized by episodes of cutaneous or submucosal edema, most commonly affecting the skin, the abdomen, and the upper respiratory tract. The most common cause of HAE is either a deficiency (type
Francesco Giardino, Andrea Caruso, Simone Giosuè Longhitano, Lorena Domenica Campanello   +3 more
doaj   +1 more source

Kinin B1- and B2-Receptor Subtypes Contract Isolated Bovine Ciliary Muscle: Their Role in Ocular Lens Function and Intraocular Pressure Reduction

Pharmaceuticals
Background: Bradykinin is an endogenously produced nonapeptide with many physiological and pathological functions that are mediated by two pharmacologically defined receptor subtypes, B1- and B2-receptors.
Najam A. Sharif, Madura Kulkarni-Chitnis, Anthonia Okolie, Ya Fatou Njie-Mbye, Sunny E. Ohia   +4 more
doaj   +1 more source

Icatibant, an inhibitor of bradykinin receptor 2, for hereditary angioedema attacks: prospective experimental single-cohort study

São Paulo Medical Journal
CONTEXT AND OBJECTIVE: Hereditary angioedema (HAE) with C1 inhibitor deficiency manifests as recurrent episodes of edema involving the skin, upper respiratory tract and gastrointestinal tract. It can be lethal due to asphyxia.
Regis Albuquerque Campos, Solange Oliveira Rodrigues Valle, Alfeu Tavares França, Elisabete Cordeiro, Faradiba Sarquis Serpa, Yara Ferreira Mello, Teresinha Malheiros, Eliana Toledo, Elie Mansour, Gustavo Fusaro, Anete Sevciovic Grumach   +10 more
doaj   +1 more source

Valsartan/Sacubitril induced isolated angioedema of uvula: A case report

Heliyon
Objective: To report a case of drug-induced isolated angioedema secondary to the use of Entresto (Valsartan/Sacubitril). Case summary: A 75-year-old White man presented with swelling of the uvula with a normal tongue shape and gradual onset of speech ...
Maisa A. Nazzal, Abbas Iter, Ameed Q. Dawabsheh, Majd A. Bsharat   +3 more
doaj   +1 more source

Management of acute attacks of hereditary angioedema: potential role of icatibant

Vascular Health and Risk Management, 2010
Hilary J LonghurstDepartment of Immunology, Barts and The London NHS Trust, London, UKAbstract: Icatibant (Firazyr®) is a novel subcutaneous treatment recently licensed in the European Union for acute hereditary angioedema. Hereditary angioedema,
Hilary J Longhurst
doaj