Results 1 to 10 of about 165,387 (95)

Thick collagen-based 3D matrices including growth factors to induce neurite outgrowth [PDF]

Acta Biomaterialia 8, 9 (2012) 3302-3312, 2012
Designing synthetic microenvironments for cellular investigations is a very active area of research at the crossroads of cell biology and materials science. The present work describes the design and functionalization of a three-dimensional (3D) culture support dedicated to the study of neurite outgrowth from neural cells.
arxiv   +1 more source

Neurotrophic Effects of Intermittent Fasting, Calorie Restriction and Exercise: A Review and Annotated Bibliography [PDF]

arXiv, 2023
In the last decades, important progress has been achieved in the understanding of the neurotrophic effects of intermittent fasting (IF), caloric restriction (CR) and exercise. Improved neuroprotection, synaptic plasticity and adult neurogenesis (NSPAN) are essential examples of these neurotrophic effects. The importance in this respect of the metabolic
arxiv  

The simulation of the activity dependent neural network growth [PDF]

, 2009
It is currently accepted that cortical maps are dynamic constructions that are altered in response to external input. Experience-dependent structural changes in cortical microcurcuts lead to changes of activity, i.e. to changes in information encoded.
arxiv   +1 more source

Photoacoustic Silk Scaffolds for Neural stimulation and Regeneration [PDF]

arXiv, 2021
Neural interfaces using biocompatible scaffolds provide crucial properties for the functional repair of nerve injuries and neurodegenerative diseases, including cell adhesion, structural support, and mass transport. Neural stimulation has also been found to be effective in promoting neural regeneration.
arxiv  

p75NTR as a Molecular Memory Switch [PDF]

, 2019
In recent years, many molecular and environmental factors have been studied to understand how synaptic plasticity is modulated. Sleep, as an evolutionary conserved biological function, has shown to be a critical player for the consolidation and filtering of synaptic circuitry underlying memory traces.
arxiv   +1 more source

Score predictor factor analysis: Reproducing observed covariances by means of factor score predictors [PDF]

Front. Psychol. 10:1895 (2019), 2019
The model implied by factor score predictors does not reproduce the non-diagonal elements of the observed covariance matrix as well as the factor loadings. It is therefore investigated whether it is possible to estimate factor loadings for which the model implied by the factor score predictors optimally reproduces the non-diagonal elements of the ...
arxiv   +1 more source

Adaptive Sparse Structure Development with Pruning and Regeneration for Spiking Neural Networks [PDF]

arXiv, 2022
Spiking Neural Networks (SNNs) are more biologically plausible and computationally efficient. Therefore, SNNs have the natural advantage of drawing the sparse structural plasticity of brain development to alleviate the energy problems of deep neural networks caused by their complex and fixed structures. However, previous SNNs compression works are lack
arxiv  

The trade-off between factor score determinacy and the preservation of inter-factor correlations [PDF]

arXiv, 2023
Regression factor score predictors have the maximum factor score determinacy, i.e., the maximum correlation with the corresponding factor, but they do not have the same inter-correlations as the factors. As it might be useful to compute factor score predictors that have the same inter-correlations as the factors, correlation-preserving factor score ...
arxiv  

5-HT2A mediated plasticity as a target in major depression: a narrative review connecting the dots from neurobiology to cognition and psychology [PDF]

arXiv, 2020
As the world's first primary morbidity factor, depression has a considerable impact on both an individual as well as a societal level. despite their discovery several decades ago, classical antidepressants have been shown to provide limited benefits against this condition.
arxiv  

Early reduced dopaminergic tone mediated by D3 receptor and dopamine transporter in absence epileptogenesis [PDF]

Epilepsia, 2019, 60 (10), pp.2128-2140
Abstract Objective In Genetic Absence Epilepsy Rats From Strasbourg ( GAERS s), epileptogenesis takes place during brain maturation and correlates with increased mRNA expression of D3 dopamine receptors (D3R). Whether these alterations are the consequence of seizure repetition or contribute to the development of epilepsy remains to be clarified.
arxiv   +1 more source