Results 1 to 10 of about 238,574 (373)
Brain-derived neurotrophic factor and mental disorders
Biomedical Journal, 2020 Brain-derived neurotrophic factor (BDNF) is a neurotrophin that modulates neuroplasticity in the brain, and is one of the most widely investigated molecule in psychiatric disorders.
Chin-Chuen Lin, Tiao-Lai Huang
doaj +5 more sources
The impact of brain-derived neurotrophic factor gene polymorphisms on post-stroke naming in aphasia. [PDF]
PLoS ONEPost-stroke aphasia, or language deficits after stroke, afflicts 20-30% of survivors and often persists into the chronic phase. The protein brain-derived neurotrophic factor has been identified as important for neuroplasticity, and is regulated by the ...
Matilda Randighieri +8 more
doaj +2 more sources
Journal of Rehabilitation Medicine, 2019 Background: The pathophysiology of fibromyalgia includes central and peripheral factors. Neurotrophins, such as nerve growth factor and brain-derived neurotrophic factor, are involved in peripheral and central nervous system development of pain and ...
Anna Jablochkova +6 more
doaj +2 more sources
The effect of exercise intensity on brain derived neurotrophic factor and memory in adolescents
Environmental Health and Preventive Medicine, 2017 Background Brain derived neurotrophic factor (BDNF) seems to serve as an important regulatory mechanism in the growth and development of neurons in many areas of the brain.Insulin-like growth factor 1 (IGF-1) is related to neurogenesis and regulation of ...
Yong Kyun Jeon, Chang Ho Ha
doaj +2 more sources
Neural Regeneration Research, 2023 The trigeminal root entry zone is the zone at which the myelination switches from peripheral Schwann cells to central oligodendrocytes. Its special anatomical and physiological structure renders it susceptible to nerve injury.
Madeha Ishag Adam +8 more
doaj +1 more source
Brain-derived neurotrophic factor and inflammation in depression: Pathogenic partners in crime?
World Journal of Psychiatry, 2022 Major depressive disorder is a debilitating disorder affecting millions of people each year. Brain-derived neurotrophic factor (BDNF) and inflammation are two prominent biologic risk factors in the pathogenesis of depression that have received ...
Grace A. Porter, J. O'Connor
semanticscholar +1 more source
International Journal of Molecular Sciences, 2022 Neurotrophins, such as brain-derived neurotrophic factor (BDNF), are essential for neuronal survival and growth. The signaling cascades initiated by BDNF and its receptor are the key regulators of synaptic plasticity, which plays important role in ...
Khairunnuur Fairuz Azman, R. Zakaria
semanticscholar +1 more source
Brain-derived neurotrophic factor in Alzheimer’s disease and its pharmaceutical potential
Translational Neurodegeneration, 2022 Synaptic abnormalities are a cardinal feature of Alzheimer’s disease (AD) that are known to arise as the disease progresses. A growing body of evidence suggests that pathological alterations to neuronal circuits and synapses may provide a mechanistic ...
Li Gao +3 more
semanticscholar +1 more source
Frontiers in Physiology, 2022 Background: Aerobic exercise could produce a positive effect on the brain by releasing brain-derived neurotrophic factor (BDNF). In untrained healthy humans there seems to be a linear correlation between exercise duration and the positive effect of acute
Kegang Zhao +7 more
doaj +1 more source
The role of brain derived neurotrophic factor in central nervous system
Frontiers in Aging Neuroscience, 2022 Brain derived neurotrophic factor (BDNF) has multiple biological functions which are mediated by the activation of two receptors, tropomyosin receptor kinase B (TrkB) receptor and the p75 neurotrophin receptor, involving in physiological and pathological
Yiyi Li +11 more
semanticscholar +1 more source