Nerve growth factor in brain diseases [PDF]
The nerve growth factor (NGF) belongs to a family of proteins termed neurotrophins, consisting of NGF, brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), NT-4/5 and NT-6.
Attilia, Maria Luisa+12 more
core +2 more sources
Visualizing Genetic Influences on Human Brain Functions [PDF]
Egan and colleagues (2003), in this issue of Cell, integrate genetics and functional brain imaging by showing that variation in the human brain-derived neurotrophic factor (BDNF) gene is associated with variation in episodic memory ability and in ...
Gabrieli, John D.E., Preston, Alison R.
core +1 more source
Upregulation of Neurotrophic Factors Selectively in Frontal Cortex in Response to Olfactory Discrimination Learning [PDF]
We have previously shown that olfactory discrimination learning is accompanied by several forms of long-term enhancement in synaptic connections between layer II pyramidal neurons selectively in the piriform cortex.
Barkai, Edi+5 more
core +5 more sources
Activity-dependent self-wiring is a basis of structural plastisity in neural networks [PDF]
Dynamical wiring and rewiring in neural networks are carried out by activity-dependent growth and retraction of axons and dendrites, guided by gudance molecules, released by target cells. Experience-dependent structural changes in cortical microcurcuts lead to changes in activity, i.e. to changes in information encoded.
arxiv
Focused ultrasound-enhanced intranasal brain delivery of brain-derived neurotrophic factor [PDF]
The objective of this study was to unveil the potential mechanism of focused ultrasound (FUS)- enhanced intranasal (IN) brain drug delivery and assess its feasibility in the delivery of therapeutic molecules.
Acosta, Camilo+5 more
core +2 more sources
Spatial embedding of neuronal trees modeled by diffusive growth [PDF]
The relative importance of the intrinsic and extrinsic factors determining the variety of geometric shapes exhibited by dendritic trees remains unclear. This question was addressed by developing a model of the growth of dendritic trees based on diffusion-limited aggregation process.
arxiv
Brain-derived neurotrophic factor in platelet derived extracellular vesicles [PDF]
Tiivistelmä - Referat - Abstract Background. Platelets are known to contain ample amounts of brain derived neurotrophic factor. Previous spectrophotometric studies carried out in Pia Siljander’s lab have shown that BDNF is secreted from activated ...
Lindelöf, Anna-Emilia
core
The Causative and Curative Roles of Brain-Derived Neurotrophic Factor in Parkinson’s Disease [PDF]
Parkinson’s disease (PD) is characterized by the activation of degenerative and inflammatory processes in brain circuits that control movement and, according to the degree of progression of the damage, can cause neuropsychological disorders such as ...
Barrientos-Bonilla, Abril Alondra+9 more
core +2 more sources
Prenatal and Early Postnatal Exposure to Cigarette Smoke Decreases BDNF/TrkB Signaling and Increases Abnormal Behaviors Later in Life [PDF]
Background: Cigarette smoke exposure during prenatal and early postnatal periods increases the incidence of a variety of abnormal behaviors later in life.
Benders, Katherine M., MS+3 more
core +1 more source
Dynamic Image-Based Modelling of Kidney Branching Morphogenesis [PDF]
Kidney branching morphogenesis has been studied extensively, but the mechanism that defines the branch points is still elusive. Here we obtained a 2D movie of kidney branching morphogenesis in culture to test different models of branching morphogenesis with physiological growth dynamics. We carried out image segmentation and calculated the displacement
arxiv