The Role of Brain-Derived Neurotrophic Factor in Epileptogenesis: an Update [PDF]
Frontiers in Pharmacology, 2021 Epilepsy, which is characterized by spontaneous recurrent seizures, is one of the most common and serious chronic neurological diseases in the world. 30% patients failed to control seizures with multiple anti-seizure epileptic drugs, leading to serious outcomes. The pathogenesis of epilepsy is very complex and remains unclear.
Xinyi Wang, Kai Zhong, Zhe Hu
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Progesterone, brain-derived neurotrophic factor and neuroprotection [PDF]
Neuroscience, 2013 While the effects of progesterone in the CNS, like those of estrogen, have generally been considered within the context of reproductive function, growing evidence supports its importance in regulating non-reproductive functions including cognition and affect.
Chang Su, Meharvan Singh
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S100B protein, brain-derived neurotrophic factor, and glial cell line-derived neurotrophic factor in human milk. [PDF]
PLoS ONE, 2011 Human milk contains a wide variety of nutrients that contribute to the fulfillment of its functions, which include the regulation of newborn development.
Ruisong Li +3 more
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Nerve growth factor, brain-derived neurotrophic factor, and the chronobiology of mood: a new insight into the "neurotrophic hypothesis" [PDF]
, 2015 The light information pathways and their relationship with the body rhythms have generated a new insight into the neurobiology and the neurobehavioral sciences, as well as into the clinical approaches to human diseases associated with disruption of ...
IANNITELLI, ANGELA +2 more
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Brain-derived neurotrophic factor and schizophrenia
Psychiatric Genetics, 2019 The brain-derived neurotrophic factor (BDNF) is a secretory growth factor that promotes neuronal proliferation and survival, synaptic plasticity and long-term potentiation in the central nervous system. Brain-derived neurotrophic factor biosynthesis and secretion are chrono-topically regulated processes at the cellular level, accounting for specific ...
Gianluca Ursini +2 more
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Bipolar disorder, brain-derived neurotrophic factor (BDNF) Val66Met polymorphism and brain morphology [PDF]
, 2011 10.1371/journal.pone.0038469PLoS ...
Allison Ashley-Koch +7 more
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A single brain-derived neurotrophic factor infusion into the dorsomedial prefrontal cortex attenuates cocaine self-administration-induced phosphorylation of synapsin in the nucleus accumbens during early withdrawal [PDF]
, 2014 BACKGROUND: Dysregulation in the prefrontal cortex-nucleus accumbens pathway has been implicated in cocaine addiction. We have previously demonstrated that one intra-dorsomedial prefrontal cortex brain-derived neurotrophic factor (BDNF) infusion ...
Eisenstein, Sarah A +3 more
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Brain-derived neurotrophic factor and cocaine addiction [PDF]
Brain Research, 2010 The effects of brain-derived neurotrophic factor (BDNF) on cocaine-seeking are brain region-specific. Infusion of BDNF into subcortical structures, like the nucleus accumbens and ventral tegmental area, enhances cocaine-induced behavioral sensitization and cocaine-seeking. Conversely, repeated administration of BDNF antiserum into the nucleus accumbens
William J. Berglind +2 more
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Genetically engineered mesenchymal stem cells as a proposed therapeutic for Huntington's disease. [PDF]
, 2011 There is much interest in the use of mesenchymal stem cells/marrow stromal cells (MSC) to treat neurodegenerative disorders, in particular those that are fatal and difficult to treat, such as Huntington's disease.
Annett, Geralyn +14 more
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Neural Regeneration Research, 2017 Cytoskeletal proteins are involved in neuronal survival. Brain-derived neurotrophic factor can increase expression of cytoskeletal proteins during regeneration after axonal injury.
Tao Chen +7 more
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