Results 31 to 40 of about 187,908 (321)

S100B protein, brain-derived neurotrophic factor, and glial cell line-derived neurotrophic factor in human milk. [PDF]

open access: yesPLoS ONE, 2011
Human milk contains a wide variety of nutrients that contribute to the fulfillment of its functions, which include the regulation of newborn development.
Ruisong Li   +3 more
doaj   +1 more source

Neural stem cells over-expressing brain-derived neurotrophic factor promote neuronal survival and cytoskeletal protein expression in traumatic brain injury sites

open access: yesNeural Regeneration Research, 2017
Cytoskeletal proteins are involved in neuronal survival. Brain-derived neurotrophic factor can increase expression of cytoskeletal proteins during regeneration after axonal injury.
Tao Chen   +7 more
doaj   +1 more source

TrkB signaling is required for postnatal survival of CNS neurons and protects hippocampal and motor neurons from axotomy-induced cell death [PDF]

open access: yes, 1997
Newborn mice carrying targeted mutations in genes encoding neurotrophins or their signaling Trk receptors display severe neuronal deficits in the peripheral nervous system but not in the CNS. In this study, we show that trkB (¿/¿) mice have a significant
Alcántara Horrillo, Soledad   +5 more
core   +1 more source

Brain region–specific roles of brain-derived neurotrophic factor in social stress–induced depressive-like behavior

open access: yesNeural Regeneration Research
Brain-derived neurotrophic factor is a key factor in stress adaptation and avoidance of a social stress behavioral response. Recent studies have shown that brain-derived neurotrophic factor expression in stressed mice is brain region–specific ...
Man Han   +9 more
doaj   +1 more source

Brain-derived neurotrophic factor and coronary artery disease

open access: yesRussian Open Medical Journal, 2022
Coronary artery disease (CAD) is defined as myocardial damage developing as a result of its organic and functional changes, and leading to impaired blood flow through the coronary arteries.
Oksana Yu. Kytikova   +5 more
doaj   +1 more source

Neurotrophins Role in Depression Neurobiology: A Review of Basic and Clinical Evidence [PDF]

open access: yes, 2011
Depression is a neuropsychiatric disorder affecting a huge percentage of the active population especially in developed countries. Research has devoted much of its attention to this problematic and many drugs have been developed and are currently ...
Berrocoso Domínguez, Esther María   +4 more
core   +4 more sources

The glycoside oleandrin reduces glioma growth with direct and indirect effects on tumor cells [PDF]

open access: yes, 2017
Oleandrin is a glycoside that inhibits the ubiquitous enzyme Na(+)/K(+)-ATPase. In addition to its known effects on cardiac muscle, recent in vitro and in vivo evidence highlighted its potential for anticancer properties. Here, we evaluated for the first
CHECE, Giuseppina   +11 more
core   +1 more source

Effect of brain-derived neurotrophic factor on the formation of psycho-vegetative syndrome with brain injury [PDF]

open access: yesСаратовский научно-медицинский журнал, 2016
Aim: to determine the role of brain-derived neurotrophic factor in the formation and forecasting of psycho-vegetative syndrome in patients with cerebral mild to moderate injury. Material and Methods.
Selyanina N.V., Karakulova J.V.
doaj  

FSD-C10: A more promising novel ROCK inhibitor than Fasudil for treatment of CNS autoimmunity. [PDF]

open access: yes, 2015
Rho-Rho kinase (Rho-ROCK) triggers an intracellular signalling cascade that regulates cell survival, death, adhesion, migration, neurite outgrowth and retraction and influences the generation and development of several neurological disorders.
Chai, Zhi   +12 more
core   +2 more sources

Signaling pathways linking behavior to neurogenesis in healthy brain and disease [PDF]

open access: yes, 2020
Self-repair of the adult brain is limited – most diseases lack effective therapy. In order to better understand how a regenerative response can be achieved, studying mechanisms shaping the neurogenic niche, from environmental factors to intrinsic ...
Klempin, Friederike
core   +1 more source

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