Results 91 to 100 of about 2,666,950 (303)

Depression among medical students in Bangladesh: a systematic review and meta-analysis protocol on prevalence and associated factors

BMJ Open
Introduction Depression, affecting 350 million people globally, is notably prevalent among medical students, particularly in South Asia, including Bangladesh.
Mantaka Rahman, Imtiaz Abdullah, Nusrat Fatema   +2 more
doaj   +1 more source

Psychological Stress Associated Bile Acid Reprogramming Promotes Hepatocellular Carcinoma Progression

Advanced Science, EarlyView.
Depression is increasingly recognized as a risk factor for chronic diseases, yet its biological impact on cancer remains unclear. Using data from more than 490 000 participants across three international cohorts, we show that depression significantly increases the risk of liver cancer.
Ruijiang Zeng, Mengmeng Wang, Kang Wang, Zhuo Xing, Yulong Hong, Tongtong Li, Geng Zong, Chong Yang, Dan Zhang, Zhangling Chen, Xin Jin   +10 more
wiley   +1 more source

Microalgae Hybrid Biosystem for Enhanced Oral Delivery of Rifaximin in Hepatic Encephalopathy Treatment

Advanced Science, EarlyView.
The microalgae‐nanoparticle hybrid system with antibacterial activity can improve the oral delivery and therapeutic efficiency for hepatic encephalopathy treatment. Oral administration of the system can reduced systemic ammonia levels, enhanced intestinal barrier function, attenuated systemic and neuroinflammation, ameliorated cognitive impairments ...
Kaiyue Wang, Xueting Huang, Lingxiao Yang, Jin Liu, Lei Lei, Shaomin Zou, Kai Wang, Min Zhou, Zhe Tang   +8 more
wiley   +1 more source

Role of the brain-gut axis in gastrointestinal cancer

World Journal of Clinical Cases, 2019
Several studies have largely focused on the significant role of the nervous and immune systems in the process of tumorigenesis, including tumor growth, proliferation, apoptosis, and metastasis. The brain-gut-axis is a new paradigm in neuroscience, which describes the biochemical signaling between the gastrointestinal (GI) tract and the central nervous ...
Di, Yang-Zi, Han, Bo-Sheng, Di, Jun-Mao, Liu, Wei-Yan, Tang, Qiang   +4 more
openaire   +2 more sources

Multiscale Spatial Fusion Feature‐Driven Characterization of Gastric Cancer Invasive Margins: A Multicenter Cohort Study for Preoperative Accurate Differentiation Between T4a and T4b Subtypes

Advanced Science, EarlyView.
This study develops a multi‐dimensional vision Transformer‐based model, GAVR, to accurately distinguish gastric cancer T4a/b stages preoperatively. Validated across multi‐center cohorts, it achieves excellent performance and significantly improves radiologists’ diagnostic accuracy, offering a promising tool for clinical decision‐making.
Guoliang Zheng, Xiaomiao Chai, Peng Jin, Xin Xin, Yingjie Li, Chun Yang, Jia Wei, Zishuo Yan, Jingyu Zhang, Qianning Zhao, Yingchen Han, Ning Zhang, Fuze Li, Bo Qiao, Huan Wang, Huachuan Zheng, Yan Li, Xin Zhang, Yan Zhao, Wenjun Mao, Jing Zhang   +20 more
wiley   +1 more source

Molecular anatomy of the gut-brain axis revealed with transgenic technologies: implications in metabolic research

Frontiers in Neuroscience, 2013
Neurons residing in the gut-brain axis remain understudied despite their important role in coordinating metabolic functions. This lack of knowledge is observed, in part, because labeling gut-brain axis neurons and their connections using conventional ...
Laurent eGautron
doaj   +1 more source

Gut microbiota & gut-brain axis summary document

, 2017
This document covers recent science linking the gut microbiota to brain-related disorders via the gut-brain axis. It contains a summary written by Paul Enck and Kristina Campbell, and an editorial by Premysl Bercik summarizing the research to date on the
Andreu Prados (3665137), premysl bercik (3689356), paul enck (3232590), Kristina Campbell (3232332)   +3 more
core   +1 more source

Intermittent Fasting Restores Cardiac Lipid Homeostasis in Diabetic Cardiomyopathy in Association With Akkermansia Muciniphila and 1‐methyl‐L‐histidine

Advanced Science, EarlyView.
Intermittent fasting reshapes the gut microbiota in diabetic cardiomyopathy, restoring Akkermansia muciniphila and the microbiota‐associated metabolite 1‐methyl‐L‐histidine. This shift is linked to improved cardiac lipid homeostasis, reduced lipid peroxidation, and attenuated myocardial injury, highlighting a gut microbiota–metabolite–lipid axis in ...
Kaiyuan Jiang, Fen Xiong, Yiwen Peng, Lingfei Meng, Xinran Wang, Yingruo Xu, Tian Tang, Hongchang Gao   +7 more
wiley   +1 more source

Age-related cognitive decline is associated with microbiota-gut-brain axis disorders and neuroinflammation in mice

, 2021
Age-related cognitive decline is associated with microbiota-gut-brain axis disorders and neuroinflammation in ...
ML Wu (14473254), XQ Yang (14473257), Wei Duan (13099662), L Xue (5099372), JR Du (14468262)   +4 more
core  

Microbiota-gut brain axis involvement in neuropsychiatric disorders [PDF]

, 2019
Introduction: The microbiota-gut brain (MGB) axis is the bidirectional communication between the intestinal microbiota and the brain. An increasing body of preclinical and clinical evidence has revealed that the gut microbial ecosystem can affect ...
Preda A., Tagliabue A., Iannetti, P, Guiducci L., Ferraris, C, Ronchi, Francesca, Luongo G., Striano P., Russo, E, Citraro, R, Selmer, K, Verrotti, A, Albani D., Baldelli, Pietro, Cattaneo, Anna, Carotenuto, Marco, Mainardi P., Tagliabue, A, Spalice A., Guiducci, Letizia, Ferraris C., Zara, F, Spalice, Alberto, Iannone, LF, Carotenuto M., Segata, N, Zimmermann, J, Verrotti, Alberto, Verrotti A., Russo E., Blottiere, HM, Ronchi, F, Guiducci, L, Spalice, A, Selmer, Kaja, Sisodiya, Sanjay, Minetti C., Iannone L. F., Cattaneo, Annamaria, Segata N., Santocchi E., Blottière, Hervé M, Minetti, Carlo, Baldelli, P, Giordano, Carmen, Striano, Pasquale, Petretto, Andrea, Carotenuto, M, Provasi, Stefania, Provasi, S, Russo, Emilio, Albani, D, Belcastro, Vincenzo, Zara, Federico, Zimmermann J., Provasi S., Cattaneo, A, Belcastro, V, Citraro R., Iannetti, Paola, Luongo, G, Iannone, Luigi Francesco, Santocchi, Elisa, Preda, Alberto, Mainardi, Paolo, Segata, Nicola, Cattaneo A., Belcastro V., Zimmermann, Jakob, Giordano C., Tagliabue, Anna, Clarke G., Iannetti P., Ferraris, Cinzia, Giordano, C, Zara F., Minetti, C, Clarke, G, Ronchi F., Baldelli P., Petretto A., Mainardi, P, Sisodiya S., Blottiere, Hervé H, Citraro, Rita, Pedersen S., Pedersen, S, Albani, Diego, Blottiere H. M., Luongo, Gaia, Santocchi, E, Preda, A, Petretto, A, Selmer K., Clarke, Gerard, Sisodiya, S, Pedersen, Sigrid, Striano, Pasquale., Blottière, Hervé M., Cattaneo, Annamaria; id_orcid, Striano, P   +100 more
core   +1 more source