Bibliometric Analysis Study on the Mechanisms of Brain Energy Metabolism Disorders in Alzheimer's Disease From 2000 to 2020 [PDF]
Frontiers in Neurology, 2021 Alzheimer's disease (AD) is currently one of the main diseases afflicting the elderly in the world. In recent years, more and more studies have shown that brain energy metabolism disorders are the key pathogenic factors and main early pathological ...
Yi-Hong Du +8 more
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Astrocytes as Key Regulators of Brain Energy Metabolism: New Therapeutic Perspectives [PDF]
Frontiers in Physiology, 2022 Astrocytes play key roles in the regulation of brain energy metabolism, which has a major impact on brain functions, including memory, neuroprotection, resistance to oxidative stress and homeostatic tone.
Elidie Beard +4 more
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Acute Inflammation Alters Brain Energy Metabolism in Mice and Humans: Role in Suppressed Spontaneous Activity, Impaired Cognition, and Delirium [PDF]
J Neurosci, 2020 Systemic infection triggers a spectrum of metabolic and behavioral changes, collectively termed sickness behavior, which while adaptive, can affect mood and cognition.
J. Kealy +8 more
semanticscholar +4 more sources
Impaired Brain Energy Metabolism: Involvement in Depression and Hypothyroidism [PDF]
Frontiers in Neuroscience, 2020 Although hypothyroidism appears to be an important factor in the pathogenesis of depression, the impact of thyroid hormones on the bioenergetics of the adult brain is still poorly known.
Katarzyna Głombik +3 more
doaj +3 more sources
Energy Metabolism Decline in the Aging Brain—Pathogenesis of Neurodegenerative Disorders [PDF]
Metabolites, 2020 There is a growing body of evidencethat indicates that the aging of the brain results from the decline of energy metabolism. In particular, the neuronal metabolism of glucose declines steadily, resulting in a growing deficit of adenosine triphosphate ...
Janusz Wiesław Błaszczyk
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HIV-Tat and Cocaine Impact Brain Energy Metabolism: Redox Modification and Mitochondrial Biogenesis Influence NRF Transcription-Mediated Neurodegeneration [PDF]
Mol Neurobiol, 2020 HIV infection and drugs of abuse induce oxidative stress and redox imbalance, which cause neurodegeneration. The mechanisms by which HIV infection and cocaine consumption affect astrocyte energy metabolism, and how this leads to neurodegenerative ...
Kalaiselvi Sivalingam +3 more
semanticscholar +4 more sources
Ketone bodies mediate alterations in brain energy metabolism and biomarkers of Alzheimer’s disease [PDF]
Front Neurosci, 2023 Alzheimer’s disease (AD) is the most common form of dementia. AD is a progressive neurodegenerative disorder characterized by cognitive dysfunction, including learning and memory deficits, and behavioral changes.
Matin Ramezani +13 more
semanticscholar +2 more sources
Brain Energy Metabolism: Astrocytes in Neurodegenerative Diseases [PDF]
CNS Neurosci Ther, 2022 Astrocytes are the most abundant cells in the brain. They have many important functions in the central nervous system (CNS), including the maintenance of glutamate and ion homeostasis, the elimination of oxidative stress, energy storage in glycogen ...
Zhenlei Chen +6 more
semanticscholar +2 more sources
Brain Energy Metabolism in Ischemic Stroke: Effects of Smoking and Diabetes [PDF]
Int J Mol Sci, 2022 Proper regulation of energy metabolism in the brain is crucial for maintaining brain activity in physiological and different pathophysiological conditions.
A. Sifat +4 more
semanticscholar +2 more sources
Brain energy metabolism: A roadmap for future research [PDF]
J NeurochemAlthough we have learned much about how the brain fuels its functions over the last decades, there remains much still to discover in an organ that is so complex.
Caroline D. Rae +25 more
semanticscholar +2 more sources