Results 11 to 20 of about 725,765 (358)

Enlightening brain energy metabolism

Neurobiology of Disease, 2023
Brain tissue metabolism is distributed across several cell types and subcellular compartments, which activate at different times and with different temporal patterns.
L.F. Barros, I. Ruminot, P.Y. Sandoval, A. San Martín   +3 more
doaj   +4 more sources

Brain energy metabolism: A roadmap for future research. [PDF]

J Neurochem
Although we have learned much about how the brain fuels its functions over the last decades, there remains much still to discover in an organ that is so complex.
Rae CD, Baur JA, Borges K, Dienel G, Díaz-García CM, Douglass SR, Drew K, Duarte JMN, Duran J, Kann O, Kristian T, Lee-Liu D, Lindquist BE, McNay EC, Robinson MB, Rothman DL, Rowlands BD, Ryan TA, Scafidi J, Scafidi S, Shuttleworth CW, Swanson RA, Uruk G, Vardjan N, Zorec R, McKenna MC.   +25 more
europepmc   +4 more sources

Bibliometric Analysis Study on the Mechanisms of Brain Energy Metabolism Disorders in Alzheimer's Disease From 2000 to 2020 [PDF]

Frontiers in Neurology, 2021
Alzheimer's disease (AD) is currently one of the main diseases afflicting the elderly in the world. In recent years, more and more studies have shown that brain energy metabolism disorders are the key pathogenic factors and main early pathological ...
Yi-Hong Du, Yi-Hong Du, Ruo-Yu Yang, Qi Wang, Li-Yan Wang, Lei-Chao Liang, Lei Zhu, Yan Sun, Ming Cai   +8 more
doaj   +3 more sources

Astrocytes as Key Regulators of Brain Energy Metabolism: New Therapeutic Perspectives [PDF]

Frontiers in Physiology, 2022
Astrocytes play key roles in the regulation of brain energy metabolism, which has a major impact on brain functions, including memory, neuroprotection, resistance to oxidative stress and homeostatic tone.
Elidie Beard, Sylvain Lengacher, Sara Dias, Pierre J. Magistretti, Charles Finsterwald   +4 more
doaj   +3 more sources

Elucidating reaction dynamics in a model of human brain energy metabolism. [PDF]

PLoS Computational Biology
Energy metabolism is essential to brain function and Bioinformatics, but its study is experimentally challenging. Similarly, biologically accurate computational models are too complex for simple investigations.
Dimitrios G Patsatzis, Efstathios-Al Tingas, Subram Mani Sarathy, Dimitris A Goussis, Renaud Blaise Jolivet   +4 more
doaj   +3 more sources

Brain Energy Metabolism: Astrocytes in Neurodegenerative Diseases. [PDF]

CNS Neurosci Ther, 2023
Astrocytes are the most abundant cells in the brain. They have many important functions in the central nervous system (CNS), including the maintenance of glutamate and ion homeostasis, the elimination of oxidative stress, energy storage in glycogen ...
Chen Z, Yuan Z, Yang S, Zhu Y, Xue M, Zhang J, Leng L.   +6 more
europepmc   +4 more sources

Acute Inflammation Alters Brain Energy Metabolism in Mice and Humans: Role in Suppressed Spontaneous Activity, Impaired Cognition, and Delirium. [PDF]

J Neurosci, 2020
Systemic infection triggers a spectrum of metabolic and behavioral changes, collectively termed sickness behavior, which while adaptive, can affect mood and cognition.
Kealy J, Murray C, Griffin EW, Lopez-Rodriguez AB, Healy D, Tortorelli LS, Lowry JP, Watne LO, Cunningham C.   +8 more
europepmc   +4 more sources

The Effects of Early-Life Iron Deficiency on Brain Energy Metabolism. [PDF]

Neurosci Insights, 2020
Iron deficiency (ID) is one of the most prevalent nutritional deficiencies in the world. Iron deficiency in the late fetal and newborn period causes abnormal cognitive performance and emotional regulation, which can persist into adulthood despite iron ...
Bastian TW, Rao R, Tran PV, Georgieff MK.   +3 more
europepmc   +4 more sources

Impaired Brain Energy Metabolism: Involvement in Depression and Hypothyroidism [PDF]

Frontiers in Neuroscience, 2020
Although hypothyroidism appears to be an important factor in the pathogenesis of depression, the impact of thyroid hormones on the bioenergetics of the adult brain is still poorly known.
Katarzyna Głombik, Jan Detka, Anna Kurek, Bogusława Budziszewska   +3 more
doaj   +3 more sources

Ketone bodies mediate alterations in brain energy metabolism and biomarkers of Alzheimer's disease. [PDF]

Front Neurosci, 2023
Alzheimer’s disease (AD) is the most common form of dementia. AD is a progressive neurodegenerative disorder characterized by cognitive dysfunction, including learning and memory deficits, and behavioral changes.
Ramezani M, Fernando M, Eslick S, Asih PR, Shadfar S, Bandara EMS, Hillebrandt H, Meghwar S, Shahriari M, Chatterjee P, Thota R, Dias CB, Garg ML, Martins RN.   +13 more
europepmc   +2 more sources