Results 31 to 40 of about 710,108 (323)

Enlightening brain energy metabolism

Neurobiology of Disease, 2023
Brain tissue metabolism is distributed across several cell types and subcellular compartments, which activate at different times and with different temporal patterns.
L.F. Barros, I. Ruminot, P.Y. Sandoval, A. San Martín   +3 more
doaj   +1 more source

Simultaneous nicotine and oral contraceptive exposure alters brain energy metabolism and exacerbates ischemic stroke injury in female rats. [PDF]

J Cereb Blood Flow Metab, 2021
Diaz F, Raval AP.
europepmc   +3 more sources

Energy metabolism in childhood neurodevelopmental disorders

EBioMedicine, 2021
Whereas energy function in the aging brain and their related neurodegenerative diseases has been explored in some detail, there is limited knowledge about molecular mechanisms and brain networks of energy metabolism during infancy and childhood.
Oyarzábal A, Musokhranova U, Barros LF, García-Cazorla A   +3 more
doaj   +1 more source

Imaging and spectroscopic approaches to probe brain energy metabolism dysregulation in neurodegenerative diseases [PDF]

J Cereb Blood Flow Metab, 2017
G. Bonvento, J. Valette, J. Flament, F. Mochel, E. Brouillet   +4 more
semanticscholar   +2 more sources

Altered Brain Energy Metabolism Related to Astrocytes in Alzheimer's Disease

medRxiv, 2023
Increasing evidence suggests that reactive astrocytes are associated with Alzheimer's disease (AD). However, its underlying pathogenesis remains unknown.
K. Hirata, K. Matsuoka, Kenji Tagai, H. Endo, H. Tatebe, M. Ono, N. Kokubo, Asaka Oyama, H. Shinotoh, Takahata Keisuke, Takayuki Obata, Masoumeh Dehghani, Jamie Near, K. Kawamura, M. Zhang, H. Shimada, Takanori Yokota, T. Tokuda, Makoto Higuchi, Y. Takado   +19 more
semanticscholar   +1 more source

Brain Regulation of Energy Metabolism [PDF]

Endocrinology and Metabolism, 2016
In healthy individuals, energy intake is in balance with energy expenditure, which helps to maintain a normal body weight. The brain's inability to control energy homeostasis underlies the pathology of hyperphagia and obesity.
Eun Roh, Min-Seon Kim
doaj   +1 more source

Cerebral metabolic mechanisms of migraine

Chinese Journal of Contemporary Neurology and Neurosurgery, 2022
Migraine is one of the most common primary headaches, but its pathogenesis remains unclear. Recent studies have found that the onset of migraine may be a response to the imbalance of brain energy metabolism and oxidative stress, suggesting that migraine ...
JIN Hai⁃di , PAN Meng⁃xiong, CHEN Mei⁃jiao, LIU Kai⁃ming   +3 more
doaj   +1 more source

Maintenance of mitochondrial homeostasis for Alzheimer's disease: Strategies and challenges

Redox Biology, 2023
Alzheimer's disease (AD) is one of the most common neurodegenerative diseases, and its early onset is closely related to mitochondrial energy metabolism. The brain is only 2% of body weight, but consumes 20% of total energy needs.
Ying Han, Daozhou Liu, Ying Cheng, Qifeng Ji, Miao Liu, Bangle Zhang, Siyuan Zhou   +6 more
doaj   +1 more source

Homeostasis of carbohydrates and reactive oxygen species is critically changed in the brain of middle-aged mice: Molecular mechanisms and functional reasons

BBA Advances, 2023
The brain is an organ that consumes a lot of energy. In the brain, energy is required for synaptic transmission, numerous biosynthetic processes and axonal transport in neurons, and for many supportive functions of glial cells.
Maria M. Bayliak, Dmytro V. Gospodaryov, Volodymyr I. Lushchak   +2 more
doaj   +1 more source

Brain NAD Is Associated With ATP Energy Production and Membrane Phospholipid Turnover in Humans

Frontiers in Aging Neuroscience, 2020
The brain requires a large amount of energy, mostly derived from the metabolism of glucose, which decreases substantially with age and neurological diseases.
Bernard Cuenoud, Özlem Ipek, Maya Shevlyakova, Maurice Beaumont, Stephen C. Cunnane, Rolf Gruetter, Lijing Xin   +6 more
doaj   +1 more source