Results 41 to 50 of about 725,765 (358)
Brain energy metabolism: focus on astrocyte-neuron metabolic cooperation. [PDF]
Cell Metabolism, 2011 The energy requirements of the brain are very high, and tight regulatory mechanisms operate to ensure adequate spatial and temporal delivery of energy substrates in register with neuronal activity. Astrocytes-a type of glial cell-have emerged as active players in brain energy delivery, production, utilization, and storage.
M. Bélanger, I. Allaman, P. Magistretti
semanticscholar +4 more sources
Energy metabolism in childhood neurodevelopmental disorders
EBioMedicine, 2021 Whereas energy function in the aging brain and their related neurodegenerative diseases has been explored in some detail, there is limited knowledge about molecular mechanisms and brain networks of energy metabolism during infancy and childhood.
Oyarzábal A +3 more
doaj +1 more source
Altered Brain Energy Metabolism Related to Astrocytes in Alzheimer's Disease
medRxiv, 2023 Increasing evidence suggests that reactive astrocytes are associated with Alzheimer's disease (AD). However, its underlying pathogenesis remains unknown.
K. Hirata +19 more
semanticscholar +1 more source
Neuroglia and brain energy metabolism. [PDF]
Handb Clin NeurolThe glial control of energy homeostasis is of crucial importance for health and disease. Astrocytes in particular play a major role in controlling the equilibrium among adenosine 5'-triphosphate (ATP), adenosine 5'-diphosphate (ADP), adenosine 5'-monophosphate (AMP), and adenosine. Any energy crisis leads to a drop in ATP, and the resulting increase in
Peter-Okaka U, Boison D.
europepmc +3 more sources
Cerebral metabolic mechanisms of migraine
Chinese Journal of Contemporary Neurology and Neurosurgery, 2022 Migraine is one of the most common primary headaches, but its pathogenesis remains unclear. Recent studies have found that the onset of migraine may be a response to the imbalance of brain energy metabolism and oxidative stress, suggesting that migraine ...
JIN Hai⁃di +3 more
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Imaging and spectroscopic approaches to probe brain energy metabolism dysregulation in neurodegenerative diseases. [PDF]
J Cereb Blood Flow Metab, 2017 Bonvento G +4 more
europepmc +2 more sources
Maintenance of mitochondrial homeostasis for Alzheimer's disease: Strategies and challenges
Redox Biology, 2023 Alzheimer's disease (AD) is one of the most common neurodegenerative diseases, and its early onset is closely related to mitochondrial energy metabolism. The brain is only 2% of body weight, but consumes 20% of total energy needs.
Ying Han +6 more
doaj +1 more source
Brain NAD Is Associated With ATP Energy Production and Membrane Phospholipid Turnover in Humans
Frontiers in Aging Neuroscience, 2020 The brain requires a large amount of energy, mostly derived from the metabolism of glucose, which decreases substantially with age and neurological diseases.
Bernard Cuenoud +6 more
doaj +1 more source