Results 11 to 20 of about 13,017 (250)
Intracellular uptake of macromolecules by brain lymphatic endothelial cells during zebrafish embryonic development [PDF]
The lymphatic system controls fluid homeostasis and the clearance of macromolecules from interstitial compartments. In mammals brain lymphatics were only recently discovered, with significant implications for physiology and disease. We examined zebrafish
Max van Lessen +5 more
doaj +2 more sources
With the increase in the aging population, the global number of people with Alzheimer’s disease (AD) progressively increased worldwide. The situation is aggravated by the fact that there is no the effective pharmacological therapy of AD ...
Semyachkina-Glushkovskaya Oxana +16 more
doaj +2 more sources
Background: Fluids, solutes and immune cells have been demonstrated to drain from the brain and surrounding structures to the cervical lymph vessels and nodes in the neck via meningeal lymphatics, nasal lymphatics and/or lymphatic vessels associated with
Thu A. Hoang +4 more
doaj +1 more source
Established, New and Emerging Concepts in Brain Vascular Development
In this review, we discuss the state of our knowledge as it relates to embryonic brain vascular patterning in model systems zebrafish and mouse. We focus on the origins of endothelial cell and the distinguishing features of brain endothelial cells ...
Ankan Gupta +2 more
doaj +1 more source
Lymphatics: Future Perspectives Unrealized Potential
Proposed fundamental laws of biology and a model of health and disease underscore the importance of the lymphatic system. The lymphatics are responsible for two of the laws of biology and the fulcrum of health and disease balancing regeneration with ...
Philip D. Houck +2 more
core +1 more source
Recent Advances in Glioma Cancer Treatment: Conventional and Epigenetic Realms
Glioblastoma (GBM) is the most typical and aggressive form of primary brain tumor in adults, with a poor prognosis. Successful glioma treatment is hampered by ineffective medication distribution across the blood-brain barrier (BBB) and the emergence of ...
Mohsen Karami Fath +13 more
doaj +1 more source
Background and purpose The discovery of glymphatic function in the human brain has generated interest in waste clearance mechanisms in neurological disorders such as multiple sclerosis (MS). However, noninvasive in vivo functional assessment is currently
Refaat E. Gabr +3 more
doaj +1 more source
Exploiting Radiation Therapy to Restore Immune Reactivity of Glioblastoma
Glioblastoma (GBM) is among the most aggressive of brain tumors and confers a dismal prognosis despite advances in surgical technique, radiation delivery methods, chemotherapy, and tumor-treating fields.
Mara De Martino +7 more
doaj +1 more source
NEW HUMAN BODY PARTS DISCOVERED
Reports about new discoveries in human anatomy could help in the progress of medical care in term of diagnosis and management. Among the many of these was the hidden system of vessels discovered in the human brain in 2015, the anterolateral ligament of ...
Hayder J. Mubarak
doaj +6 more sources
Supplemental material, sj-pdf-1-jcb-10.1177_0271678X231179555 for Visualising and semi-quantitatively measuring brain fluid pathways, including meningeal lymphatics, in humans using widely available MRI techniques by Stefan Sennfält, Michael J ...
Yajun Cheng (1794733) +9 more
core +1 more source

