Results 41 to 50 of about 1,655,573 (298)

Breast metastasis of primary colon cancer with micrometastasis in the axillary sentinel node: A metastasis that metastasized?

Diagnostic Pathology, 2011
A case of single breast metastasis from colon adenocarcinoma, with omolateral axillary micrometastasis, is reported with a brief review of the pertinent literature.
Massarut Samuele, Memeo Lorenzo, Canzonieri Vincenzo, Perin Tiziana   +3 more
doaj   +1 more source

Potential Role of Lymphovenous Bypass in Mitigating Alzheimer's Disease Dementia

Archives of Plastic Surgery
This case report explores the therapeutic potential of lymphovenous bypass (LVB) surgery performed at the neck in neurodegenerative diseases, specifically Alzheimer's disease (AD) dementia.
Qingping Xie, Changsik John Pak, Jingeun Kwon, Sung-Chuan Chao, Joon Pio Hong   +4 more
doaj   +1 more source

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan, Lei Zhou, Jingzi ZhangBao, Hongmei Tan, Zhouzhou Wang, Chao Quan   +5 more
wiley   +1 more source

The nasal lymphatic route of CSF outflow: implications for neurodegenerative disease diagnosis and monitoring

Animal Cells and Systems
Cerebrospinal fluid (CSF) plays a crucial role in the brain's lymphatics as it traverses the central nervous system (CNS). Its primary function is to facilitate the outward transport of waste. Among the various CSF outflow pathways, the route through the
Jiwon Chae, Mina Choi, Juyoung Choi, Seung-Jun Yoo   +3 more
doaj   +1 more source

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel   +8 more
wiley   +1 more source

"Compensated hyperosmolarity" of cerebrospinal fluid and the development of hydrocephalus [PDF]

, 2013
Acute osmolar loading of cerebrospinal fluid within one lateral ventricle of dogs was examined as a cause of water extraction from the bloodstream and an increase in intracranial pressure.
Vladić, Anton, Klarica, Marijan, Miše, Branko, Radoš, Milan, Orešković, Darko   +4 more
core   +1 more source

Demonstration of chemotherapeutic-mediated changes in meningeal lymphatics in vitro, ex vivo, and in vivo

Communications Biology
Systemic chemotherapy often affects cells beyond the tumor, raising concerns about their impact on peripheral tissues, including the central nervous system (CNS).
L. Monet Roberts, Jennifer H. Hammel, Peng Jin, Jessica J. Cunningham, Sophia Schumaecker, Skylar Davis, Francesca Azar, Tzu-Yu Alkaid Feng, Maosen Wang, Melanie Rutkowski, Jennifer Munson   +10 more
doaj   +1 more source

Complex Non-sinus-associated Pachymeningeal Lymphatic Structures: Interrelationship With Blood Microvasculature

Frontiers in Physiology, 2019
The contribution of cranial dura mater vascular networks, as means for maintaining brain fluid movement and balance, and as the source of significant initiators and/or contributors to neurological disorders, has been overlooked. These networks consist of
Olga V. Glinskii, Olga V. Glinskii, Olga V. Glinskii, Olga V. Glinskii, Virginia H. Huxley, Virginia H. Huxley, Virginia H. Huxley, Leike Xie, Filiz Bunyak, Kannappan Palaniappan, Vladislav V. Glinsky, Vladislav V. Glinsky, Vladislav V. Glinsky, Vladislav V. Glinsky   +13 more
doaj   +1 more source

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

Advanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu, Lorenzo Moroni, Nicolas Lebonvallet, Vincent Flacher, Paul Wieringa   +4 more
wiley   +1 more source

Cerebrospinal fluid draining lymphatics in health and disease: advances and controversies [PDF]

The meninges, consisting of the dura, arachnoid and pia mater that surround the brain and spinal cord, have been recognized from the earliest anatomical studies.
Koh, Gou Young, Proulx, Steven T, Betsholtz, Christer, Alitalo, Kari, Engelhardt, Britta, Proulx, Steven T., Siegenthaler, Julie, McDonald, Donald M, McDonald, Donald M.   +8 more
core   +2 more sources