Results 51 to 60 of about 13,017 (250)

Evidence of connections between cerebrospinal fluid and nasal lymphatic vessels in humans, non-human primates and other mammalian species

Cerebrospinal Fluid Research, 2004
Background The parenchyma of the brain does not contain lymphatics. Consequently, it has been assumed that arachnoid projections into the cranial venous system are responsible for cerebrospinal fluid (CSF) absorption.
Armstrong Dianna, Salmasi Giselle, Papaiconomou Christina, Zakharov Andrei, Johnston Miles   +4 more
doaj   +1 more source

Neuroinflammation in Autoimmune Disease and Primary Brain Tumors: The Quest for Striking the Right Balance

Frontiers in Cellular Neuroscience, 2021
According to classical dogma, the central nervous system (CNS) is defined as an immune privileged space. The basis of this theory was rooted in an incomplete understanding of the CNS microenvironment, however, recent advances such as the identification ...
Dana Mitchell, Jack Shireman, Elizabeth A. Sierra Potchanant, Montserrat Lara-Velazquez, Mahua Dey   +4 more
doaj   +1 more source

Cerebrovascular Injuries Induce Lymphatic Invasion into Brain Parenchyma to Guide Vascular Regeneration in Zebrafish

, 2018
SUMMARYDamage to regional cerebrovascular network and neuronal tissues occurs during acute cerebrovascular diseases, such as ischemic stroke. The promotion of vascular regeneration is the most promising therapeutic approach.
Qifen Yang, Jingying Chen, Jianbo He, Lingfei Luo, Yaoguang Zhang   +4 more
core   +1 more source

MEOX1 Coordinates Autocrine‐Paracrine Programs via SPHK1/S1P to Promote Lymph Node Metastasis in Ovarian Cancer

Advanced Science, EarlyView.
In ovarian cancer, MEOX1 activates the SPHK1/S1P pathway to promote both tumor progression and tumor–stroma crosstalk. MEOX1‐dependent signaling drives CAF activation, enhances VEGF‐C expression, and stimulates lymphangiogenesis, ultimately facilitating lymph node metastasis.
Jiajia Li, Xiuling Zhi, Qianhan Lin, Yating Sun, Yihua Sun, Zulimire Abudousalamu, Mengyang Xue, Chang Zheng, Xiaotian Li, Liangqing Yao, Mo Chen   +10 more
wiley   +1 more source

The interaction between the meningeal lymphatics and blood-brain barrier

, 2018
Here we show the interaction between the meningeal lymphatic system and the blood-brain barrier (BBB) function. In normal state, the meningeal lymphatic vessels are invisible on optical coherent tomography (OCT), while during the opening of the BBB ...
Abdurashitov, Arkady S., Alla Bucharskaya, Dubrovsky, Alexander, Shushunova, Natalia A., Maslyakova, Galina N., Semyachkina-Glushkovskaya, Oxana V., Valery V. Tuchin, Natalia Shushunova, Oxana V. Semyachkina-Glushkovskaya, Pavlov, Alexey, Navolokin, Nikita A., Bucharskaya, Alla B., Galina Maslyakova, Nikita Navolokin, Kurths, Jürgen, Alexey Pavlov, Tuchin, Valery V., Alexander Dubrovsky, Juergen Kurths, Arkady Abdurashitov   +19 more
core   +2 more sources

Podoplanin immunopositive lymphatic vessels at the implant interface in a rat model of osteoporotic fractures

, 2013
Insertion of bone substitution materials accelerates healing of osteoporotic fractures. Biodegradable materials are preferred for application in osteoporotic patients to avoid a second surgery for implant replacement. Degraded implant fragments are often
Vivien Kauschke, Hartmann, Sonja, Alexander Langheinrich, Matthias Schumacher, Matthias Schnabelrauch, Hanke, Thomas, Heiss, Christian, Olaf Kilian, Kauschke, Vivien, Sonja Hartmann, Christian Heiss, Alt, Volker, Heinemann, Sascha, Marian Kampschulte, Kilian, Olaf, Thormann, Ulrich, Lips, Katrin Susanne, Langheinrich, Alexander, Schumacher, Matthias, Michael Gelinsky, Armin R Kautz, Seemun Ray, Volker Alt, Kautz, Armin R, Kampschulte, Marian, Katrin Susanne Lips, Gelinsky, Michael, Ray, Seemun, Schnettler, Reinhard, Sascha Heinemann, Reinhard Schnettler, Ulrich Thormann, Schnabelrauch, Matthias, Kautz, Armin R., Thomas Hanke   +34 more
core   +1 more source

Image_2_Do We Swallow the Waste From Our Brain?.JPEG

, 2021
Ferumoxytol, an iron oxide nanoparticle, was infused into the lateral cerebroventricle of awake rats to follow its movement and clearance from the brain using magnetic resonance imaging. Within minutes the contrast agent could be observed accumulating in
Ju Qiao (6004292), Craig F. Ferris (7123448), Codi Gharagouzloo (11348935), Praveen Kulkarni (433608), Nicole Bens (11743922), Joshua Leaston (11348923)   +5 more
core   +1 more source

Spontaneous Non‐Catalyzed Molecular Reactions and Interactions in the Human Body: Biomedical Implications

Advanced Science, EarlyView.
ABSTRACT The human body functions as a natural reactor for a vast network of chemical and biological reactions and physical interactions among small molecules, proteins, cells, and numerous other components. These reactions/interactions are essential for maintaining normal physiological functions.
Yuhao Cai, Chao Zhao
wiley   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Ayurvedic lipid based rasayans - A perspective on the preparation and pharmacological significance of lipids on the bioavailability of phytoconstituents

Journal of Ayurveda and Integrative Medicine, 2022
For thousands of years, lipid based Ayurvedic formulations have been made in India, and the craft has survived down the millennia up to the present time.
Sharadendu Bali, Suvarna Prasad, Vipin Saini   +2 more
doaj   +1 more source