Results 31 to 40 of about 13,017 (250)

Overview of the meningeal lymphatic vessels in aging and central nervous system disorders

Cell & Bioscience, 2022
In the aging process and central nervous system (CNS) diseases, the functions of the meningeal lymphatic vessels (MLVs) are impaired. Alterations in MLVs have been observed in aging-related neurodegenerative diseases, brain tumors, and even ...
Huimin Jiang, Huimin Wei, Yifan Zhou, Xuechun Xiao, Chen Zhou, Xunming Ji   +5 more
doaj   +1 more source

Blood–Brain Barrier, Lymphatic Clearance, and Recovery: Ariadne’s Thread in Labyrinths of Hypotheses [PDF]

, 2018
The peripheral lymphatic system plays a crucial role in the recovery mechanisms after many pathological changes, such as infection, trauma, vascular, or metabolic diseases.
Oxana Semyachkina-Glushkovskaya, Dmitry Postnov, Jürgen Kurths   +2 more
core   +2 more sources

Breast metastasis of primary colon cancer with micrometastasis in the axillary sentinel node: A metastasis that metastasized?

Diagnostic Pathology, 2011
A case of single breast metastasis from colon adenocarcinoma, with omolateral axillary micrometastasis, is reported with a brief review of the pertinent literature.
Massarut Samuele, Memeo Lorenzo, Canzonieri Vincenzo, Perin Tiziana   +3 more
doaj   +1 more source

Increased CSF drainage by non-invasive manipulation of cervical lymphatics [PDF]

Cerebrospinal fluid (CSF) in the subarachnoid space around the brain drains to lymph nodes in the neck, but the connections and regulation have been challenging to identify1-24. Here we used fluorescent tracers in Prox1-GFP lymphatic reporter mice to map
Won, Jinyoung, Choi, Jieun, Lee, Youngjeon, Yoon, Jin-Hui, Davis, Michael J, Kang, Hae Jin, Lim, Kyung Seob, Jeon, Chang-Yeop, Koh, Gou Young, Jin, Hokyung, Park, Hyung-Soon, Kim, Hae Jin, Jin, Cheolhwa, Jung, Junho, Baek, Seung Eun, Seo, Jincheol, Hwang, Yu Seok, Yang, Myung Jin, Hong, Seon Pyo, McDonald, Donald M   +19 more
core   +1 more source

Potential Role of Lymphovenous Bypass in Mitigating Alzheimer's Disease Dementia

Archives of Plastic Surgery
This case report explores the therapeutic potential of lymphovenous bypass (LVB) surgery performed at the neck in neurodegenerative diseases, specifically Alzheimer's disease (AD) dementia.
Qingping Xie, Changsik John Pak, Jingeun Kwon, Sung-Chuan Chao, Joon Pio Hong   +4 more
doaj   +1 more source

Cerebrospinal fluid draining lymphatics in health and disease: advances and controversies [PDF]

The meninges, consisting of the dura, arachnoid and pia mater that surround the brain and spinal cord, have been recognized from the earliest anatomical studies.
Koh, Gou Young, Proulx, Steven T, Betsholtz, Christer, Alitalo, Kari, Engelhardt, Britta, Proulx, Steven T., Siegenthaler, Julie, McDonald, Donald M, McDonald, Donald M.   +8 more
core   +1 more source

Neurofilament light chain plasma levels are associated with area of brain damage in experimental cerebral malaria. [PDF]

, 2022
Neurofilament light chain (NfL), released during central nervous injury, has evolved as a powerful serum marker of disease severity in many neurological disorders, including infectious diseases.
Bendszus, Martin, Wai, Chi Ho, Jin, Jessica, Kuhle, Jens, Heiland, Sabine, Lanzer, Michael, Cyrklaff, Marek, Maceski, Aleksandra, Genoud, Christel, Frischknecht, Friedrich, Meier, Stephanie, Hoffmann, Angelika, Sattler, Julia, Funaya, Charlotta   +13 more
core   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

The nasal lymphatic route of CSF outflow: implications for neurodegenerative disease diagnosis and monitoring

Animal Cells and Systems
Cerebrospinal fluid (CSF) plays a crucial role in the brain's lymphatics as it traverses the central nervous system (CNS). Its primary function is to facilitate the outward transport of waste. Among the various CSF outflow pathways, the route through the
Jiwon Chae, Mina Choi, Juyoung Choi, Seung-Jun Yoo   +3 more
doaj   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source