Results 271 to 280 of about 2,545,594 (299)

Standardizing a method for functional assessment of neural networks in brain organoids.

Journal of Neuroscience Methods
During the last decade brain organoids have emerged as an attractive model system, allowing stem cells to be differentiated into complex 3D models, recapitulating many aspects of human brain development.
M. Oliva, J. Bourke, D. Kornienko, C. Mattei, M. Mao, A. Kuanyshbek, D. Ovchinnikov, A. Bryson, TJ Karle, S. Maljevic, S. Petrou   +10 more
semanticscholar   +1 more source

hPSCs-derived brain organoids for disease modeling, toxicity testing and drug evaluation.

Experimental Neurology
Due to the differences and variances in genetic background, in vitro and animal models cannot meet the modern medical exploration of real human brain structure and function.
Na Xie, Jinrong Bai, Ya Hou, Jia Liu, Yi Zhang, Xianli Meng, Xiaobo Wang   +6 more
semanticscholar   +1 more source

Multiscale engineering of brain organoids for disease modeling

Advanced Drug Delivery Reviews
Brain organoids hold great potential for modeling human brain development and pathogenesis. They recapitulate certain aspects of the transcriptional trajectory, cellular diversity, tissue architecture and functions of the developing brain. In this review,
Cong Xu, Alia Alameri, W. Leong, Emily L. Johnson, Zaozao Chen, Bin Xu, Kam W. Leong   +6 more
semanticscholar   +1 more source

Brain Organoids in the Study of Psychiatric Disorders

JAMA Psychiatry
This article discusses the use of brain organoids in modeling the biological mechanisms of psychiatric disease.
Yukyeong, Lee, Paul K, Reardon, Rakesh, Karmacharya   +2 more
openaire   +2 more sources

Stretchable Mesh Nanoelectronics for 3D Single‐Cell Chronic Electrophysiology from Developing Brain Organoids

Advanced Materials, 2022
Paul Le Floch, Qiang Li, Zuwan Lin
exaly  

Human brain organoids assemble functionally integrated bilateral optic vesicles

Cell Stem Cell, 2021
Elke Gabriel, Walid Albanna, Giovanni Pasquini   +2 more
exaly  

Brain organoids fill the gap

Nature Neuroscience, 2023
openaire   +2 more sources

Differentiation of brain and retinal organoids from confluent cultures of pluripotent stem cells connected by nerve-like axonal projections of optic origin

Stem Cell Reports, 2022
Erdahl T Teber, Robin R Ali, Pengyi Yang   +2 more
exaly  

Eavesdropping on brain organoids

Nature Biotechnology
James Newton, Brandt, Priya, Rajasethupathy   +1 more
openaire   +2 more sources

Modeling Sporadic Alzheimer's Disease in Human Brain Organoids under Serum Exposure

Advanced Science, 2021
Xianwei Chen, Guoqiang Sun, E Tian
exaly