Results 101 to 110 of about 95,123 (282)

Developing a community-based breast cancer risk prediction tool for resource-poor settings

Journal of Education and Health Promotion, 2019
BACKGROUND: With an estimation of every two women newly diagnosed with breast cancer, one dies. It is accounted that 1 in 28 women is likely to develop breast cancer during her lifetime.
Divya Pillai, Shaikh Shah Hossain, Vijay Kumar Chattu   +2 more
doaj   +1 more source

Organoids and organ‐on‐a‐chip models for investigating the pathophysiology of the human reproductive system

Interdisciplinary Medicine, EarlyView.
Organoids and organ‐on‐a‐chips are advancing reproductive system research. In the female reproductive system, applications include cancer organoid models, placental chips, and hormone simulation models. For the male reproductive system, research focuses on drug resistance mechanisms, co‐culture platforms, and infertility studies. These refined in vitro
Hongqi Zhang, Shiwen Deng, Fangfang Jin, Jiayao Qu, Xiang Fan, Peng Chen, Xinrong Fan   +6 more
wiley   +1 more source

Supplementary Results from High Incidence of Protein-Truncating <i>TP53</i> Mutations in BRCA1-Related Breast Cancer

, 2023
Henne Holstege, Simon A. Joosse, Conny Th.M. van Oostrom, Petra M. Nederlof, Annemieke de Vries, Jos Jonkers   +5 more
openalex   +1 more source

FOXO3a Mediates Homologous Recombination Repair (HRR) via Transcriptional Activation of MRE11, BRCA1, BRIP1, and RAD50 [PDF]

, 2022
Gözde Inci, Madhuri Shende Warkad, Beom-Goo Kang, Na-Kyung Lee, Hong‐Won Suh, Soon Sung Lim, Jaebong Kim, Sungchan Kim, Jae‐Yong Lee   +8 more
openalex   +1 more source

Impact of organic pollutants on phenotype and gene expression in human breast cancer cells

Journal of Applied Toxicology, EarlyView.
ABSTRACT Human exposure to industrial chemical compounds is widespread and, although often beneficial, prolonged contact may contribute to disease development, including cancer. While many studies have shown organic pollutants (OP) are cytotoxic, few have explored how long‐term exposure alters cell phenotype.
Camila Confortin, Heloisa Amancio, Jessica Zablocki da Luz, Aliciane de Almeida Roque, Tugstênio Lima de Souza, José Eduardo Vargas, Ciro Alberto de Oliveira Ribeiro, Francisco Filipak Neto   +7 more
wiley   +1 more source

Supplemental Figure 5 from Repair versus Checkpoint Functions of BRCA1 Are Differentially Regulated by Site of Chromatin Binding

, 2023
Michael H. Goldstein, Michael B. Kastan
openalex   +1 more source

Small Nucleotide Variant Analysis Using RNA Fusion Panel (SMURF): Making the Most of RNAseq Data in Solid Tumours

Journal of Clinical Laboratory Analysis, EarlyView.
RNA‐based fusion panels using targeted next‐generation sequencing of formalin‐fixed paraffin‐embedded (FFPE) tumour tissue specimens have been used for a few years from patients with various tumour types to detect rearrangements/fusions. Using the bioinformatic approaches the data obtained from RNA sequencing (RNAseq) can also be used for small ...
Pranav Dorwal, Julie Robin, Broden Krause, Patricia Pyrchla, Bin Yuan, Robert Quach, Anna Fong Na Goh, Pamela Htain, Noel Djitro, Amit Kumar, Liyan Song, Priscillia Siswara, Suzanne Svobodova, Peter Kaub, Beena Kumar   +14 more
wiley   +1 more source

Gene Expression Profiling in Hereditary, BRCA1-linked Breast Cancer: Preliminary Report [PDF]

, 2006
Volha Dudaladava, Michał Jarząb, Ewa Stobiecka, Ewa Chmielik, Krzysztof Simek, Tomasz Huzarski, Jan Lubiński, Jolanta Pamuła‐Piłat, Wioletta Pękala, Ewa Grzybowska, Katarzyna Marta Lisowska   +10 more
openalex   +1 more source

BRCA1 and BRCA2 screening of nine Chilean founder mutations through allelic-discrimination and real-time PCR in breast/ovarian cancer patients [PDF]

, 2022
Carolina Álvarez, Victoria Ortega-Hernández, Aracely Cortez, Pilar Carvallo   +3 more
openalex   +1 more source

BMI and Breast Subcutaneous Fat

Journal of Ultrasound in Medicine, EarlyView.
Objectives Obesity is closely associated with the occurrence and progression of breast cancer. While body mass index (BMI) is widely used to diagnose obesity, it has certain limitations. Subcutaneous fat thickness (SFT) also serves as an indicator of body composition. However, studies on breast SFT are scarce.
Shiyu Wang, Jin Zhou, Yunxia Huang, Dongdong Zheng, Ruoqing Hou, Shichong Zhou   +5 more
wiley   +1 more source