Results 171 to 180 of about 158,234 (188)

BRCA1 regulation of transcription

Cancer Letters, 2006
BRCA1, a tumor suppressor gene on chromosome 17q21, was identified in 1994 based on its linkage to hereditary breast and ovarian cancer syndromes. The BRCA1 gene encodes a 220 kDa nuclear phosphoprotein. Studies aimed at elucidating the mechanisms of its tumor suppressor activity have revealed, in part, that BRCA1 participates in the DNA damage ...
Eliot M, Rosen, Saijun, Fan, Yongxian, Ma   +2 more
openaire   +2 more sources

BRCA1 mutations and phenotype

Journal of Cancer Research and Clinical Oncology, 1997
More than 100 mutations have been described for the breast-cancer-susceptibility gene BRCA1. The paper describes phenotypical aspects of three selected mutations located at the beginning, in the middle, and at the end of the gene. A remarkable decrease of the age of diagnosis of the mammary carcinoma is observed with increasing length of the putative ...
K, Grade, K, Höffken, R, Kath, A, Nothnagel, E, Bender, S, Scherneck   +5 more
openaire   +2 more sources

BRCA1

The Missouri Review, 2009
Alexander K. C. Leung, Marcus Schmitt, Christie P. Thomas, Cord Sunderkötter, Meinhard Schiller, Thomas Schwarz, Mark Berneburg, Alfried Kohlschütter, Lorenzo Cerroni, Haner Direskeneli, Kenneth Calamia, Gloria L. David, Darryl C. Zeldin, Bärbel Schütte, Lee A. Denson, Andreas Erhardt, Ralf Kubitz, Dieter Häussinger, Wendy M. Sealey, Donald M. Mock, Barry Wolf, Johannes Schumacher, Peter Propping, Dieter Metze, Alexander K. C. Leung, Andrew L. Wong, Mark Berneburg, Thomas Schwarz, Markus Hengstschläger, Whitney A. High, Kenneth R. Shroyer, M. Elizabeth McCready, Dennis E. Bulman, Ali R. Afzal, David B. Everman, Claude Stoll, Sukran Darcan, Yu Ru Kou, You Shuei Lin, Yoichi Suzuki, Keiya Tada, Alexander K. C. Leung, Susan Kupka, Wolfgang Dietmaier, Arndt Hartmann, Raoul C. M. Hennekam, John A. Belperio, Michael P. Keane, M. Iain Smith, Robert M. Strieter, Nestor A. Molfino, Francesca Sciandra, Tom Rossenbacker, Silvia G. Priori, Marco Senzolo, Christos Triantos, Dimitrios Samonakis, Evangelos Cholongitas, Andrew K. Burroughs, Marco Mura, Markus Braun-Falco, Silke Hofmann, Leena Bruckner-Tuderman   +62 more
openaire   +2 more sources

Traffic Control for BRCA1

New England Journal of Medicine, 2010
The cellular machinery that transports BRCA1 protein to sites of DNA repair is critical to DNA integrity. Two recent studies have identified key components of this machinery.
openaire   +2 more sources

?????????????? ?????????????? 5382INSC ???????? BRCA1 ?? ??????????, ???????????? ???? ?????? ???????????????? ????????????, ?? ?????????? ???????????????? ??????????????

2021
Aims. Breast cancer ranks first among cancers of the female population in Ukraine and in most countries abroad. However, data on the mutations frequencies in Ukraine for BRCA1 gene is limited. We investigated the variation and frequency of mutations in gene BRCA1 among patients with breast cancer in three regions of Ukraine. Methods.
openaire   +1 more source

BRCA1

2017
S. Holdenrieder, P. Stieber
openaire   +2 more sources

BRCA1

Advances in Anatomic Pathology, 1994
openaire   +1 more source

BRCA1

2006
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BRCA1

2011
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???????????? ?????????????? ?? ?????????? BRCA1/2 ?? ???????????? ???? ????????????????/?????????????????? ?????? ???????????????? ????????????, ?????? ???????????????????? ?? ???????????????????? ?????????????? (??????????????)

2016
?????????????????? ???????????? ???????????????????????????? ?????????????? ?? ?????????? BRCA1/2 ?????????? ???? ?????????? ???????????????? ???????????? (??????) ?? ?????????? ?????????????? (????), ?????? ?????????? ?????????????????? ???????????????? ?????????????? ???????? ?????? ??????????????????. ???????????????????? ???????????????? 78 ????????
openaire   +1 more source