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Biological Functions of the BRCA1 Protein
Breast Disease, 1998W H, Lee +3 more
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Biological Functions of the BRCA1 and BRCA2 Proteins
1999Breast cancer is the most commonly diagnosed nondermatologic cancer in women in the United States. It is second only to lung cancer as the most frequent cause of cancer-related deaths in American women. In 1996, the American Cancer Society projected over 184,000 newly diagnosed cases of breast cancer and over 44,000 deaths secondary to invasive breast ...
Helen K. Chew +2 more
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Interaction of BRCA1 with the DNA-Dependent Protein Kinase
2004Abstract : The DNA-dependent protein kinase (DNA-PK) plays a very important role in the repair of DNA double-strand breaks generated by ionizing radiation (IR). The activation of DNA-PK in response to IR involves multiple autophosphorylations at SftQ residues of the catalytic subunit, DNA-PKcs.
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Mechanisms, regulation and functions of the unfolded protein response
Nature Reviews Molecular Cell Biology, 2020Claudio Hetz +2 more
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Biomolecular condensates at the nexus of cellular stress, protein aggregation disease and ageing
Nature Reviews Molecular Cell Biology, 2021Simon Alberti, Anthony A Hyman
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The mechanisms of integral membrane protein biogenesis
Nature Reviews Molecular Cell Biology, 2021Ramanujan Shankar Hegde, Robert J Keenan
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Derivatization with fatty acids in peptide and protein drug discovery
Nature Reviews Drug Discovery, 2022Peter Kurtzhals +2 more
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The unfolded protein response: controlling cell fate decisions under ER stress and beyond
Nature Reviews Molecular Cell Biology, 2012Claudio Hetz
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