Results 91 to 100 of about 14,160 (163)

Proteomics- and BRET- screens identify SPRY2 as a Ras effector that impacts its membrane organization. [PDF]

iScience
Pavic K, Hood FE, Duval CJ, Manoharan GB, Laurini C, Siddiqui FA, Mo SPL, Prior IA, Abankwa DK.   +8 more
europepmc   +1 more source

Class A and B GPCRs trigger rapid Gα_s translocation to late and slow recycling endosomes. [PDF]

Commun Biol
Laniel A, Holleran B, Labonté É, Grondin SJ, Boudreault PL, Lavoie C.   +5 more
europepmc   +1 more source

Negative Allosteric Modulation of Agonist-Induced M₂ Muscarinic Receptor/β-Arrestin Interaction by Serum Autoantibodies from Patients with Chronic Chagas Disease. [PDF]

Cells
Carrera Páez LC, Beltrame SP, Auger SR, Sabra AH, Bilder CR, Irurzun IM, Waldner CI, Goin JC.   +7 more
europepmc   +1 more source

Development of a Genetically Encoded and Potent PDE6D Inhibitor. [PDF]

Chembiochem
Gómez-Mulas A, Schaffner-Reckinger E, Peeters H, Chippalkatti R, Dautbasic A, Smith MJ, Ismail S, Abankwa DK.   +7 more
europepmc   +1 more source

Novel <i>GNAO1</i> variant in α-helical domain reveals alternative mechanism of disease. [PDF]

Genes Dis
Ludlam WG, Domínguez-Carral J, Schteinschnaider A, Martemyanov KA, Ortigoza-Escobar JD.   +4 more
europepmc   +1 more source

A high-throughput screening approach to discover potential colorectal cancer chemotherapeutics: repurposing drugs to identify novel disruptors of 14-3-3 proteins. [PDF]

Cell Death Dis
He S, Meister D, Khan S, Mohammadzadeh A, Delgadillo Silva L, Rutter GA, Trant JF, Lim GE.   +7 more
europepmc   +1 more source

LAP2α drives breast tumorigenesis by mitigating replication stress. [PDF]

Cell Death Dis
Ma Y, Qin Y, Bao P, Wei A, Yang Z, Liu L, Liu S, Foisner R, Shi L, Zhang Q, Bao K.   +10 more
europepmc   +1 more source

Synthetic Multidomain Proteins Containing Unstructured and α‑Helical Linkers Reveal a Differential Impact of Molecular Crowding on Catalytic Activity and Conformation. [PDF]

ACS Omega
Sultana A, Geethakumari AM, Ahmed WS, Biswas KH.   +3 more
europepmc   +1 more source

Influence of PARP1 on CRISPR/Cas9 induced double strand break repair in proliferating cells. [PDF]

Comput Struct Biotechnol J
Wimmer T, Schneider J, Alabudeeb F, Türk FM, Lytvynchuk L, Stieger K.   +5 more
europepmc   +1 more source

The pathway-independent positive allosteric modulator C1 allows for the identification of active Y₄ receptor relevant positions. [PDF]

Cell Mol Life Sci
Schüß C, Vu O, Pelczyk T, Schubert M, Du Y, Stichel J, Weaver CD, Meiler J, Beck-Sickinger AG.   +8 more
europepmc   +1 more source