Results 91 to 100 of about 131,173 (232)

MERLIN: a novel BRET-based proximity biosensor for studying mitochondria–ER contact sites

Life Science Alliance, 2019
MERLIN is a novel biosensor that generates a BRET signal with a signal-to-noise ratio that is sufficient to enable sensing the proximity between the mitochondria and the ER without forcing interaction or establishing artificial connections at the MERCs ...
Vanessa Hertlein, H. Flores‐Romero, Kushal Das, Sebastian Fischer, Michael Heunemann, Maria Calleja-Felipe, S. Knafo, K. Hipp, K. Harter, J. Fitzgerald, A. García-Sáez   +10 more
semanticscholar   +1 more source

Peripheral κ opioid receptor in pain and inflammation: From molecular signalling and gene expression to drug discovery

British Journal of Pharmacology, Volume 183, Issue 17, Page 5157-5189, September 2026.
The κ opioid receptor (κ receptor, KOR) is a G protein‐coupled receptor with well established roles in analgesia and immune modulation. Although historically studied primarily in the central nervous system (CNS), growing evidence indicates that κ signalling in peripheral tissues plays an important role in regulating pain, inflammation and immune ...
Rumsha Khan, Elena C. A. Becker, Boglarka B. Bata, Christian W. Gruber   +3 more
wiley   +1 more source

The chemokine receptor‐like fourth extracellular loop of the apelin receptor differentially regulates apelin and elabela binding and signalling

British Journal of Pharmacology, Volume 183, Issue 18, Page 5641-5656, September 2026.
Abstract Background and Purpose Apelin and Elabela are endogenous ligands of the apelin receptor (apelin receptor/APJ), a GPCR involved in cardiovascular regulation and body fluid homeostasis. The human receptor contains a conserved disulfide bridge linking the N‐terminal domain to extracellular loop 3 (ECL3) via Cys19 and Cys281, forming a structural ...
Chloé Bonef, Hela Bouhsine, Carine Huynh, Marion Chaigneau, Steven Dubois, Mikel Garcia‐Marcos, Catherine Llorens‐Cortes, Denis Servent, Philippe Robin, Hervé Nozach, Isabel Alves, Xavier Iturrioz   +11 more
wiley   +1 more source

Differential Effects of Camel Milk on Insulin Receptor Signaling – Towards Understanding the Insulin-like Properties of Camel Milk

Frontiers in Endocrinology, 2016
Previous studies on the Arabian camel (Camelus dromedarius) showed beneficial effects of its milk reported in diverse models of human diseases including a substantial hypoglycemic activity.
Abdulrasheed O Abdulrahman, Mohammad A Ismael, Khaled A Alhosaini, Christelle eRame, Abdulrahman M Al-Senaidy, Joëlle eDupont, Mohammed Akli AYOUB, Mohammed Akli AYOUB, Mohammed Akli AYOUB   +8 more
doaj   +1 more source

Narrative Review on History of Point‐of‐Care Ultrasound Training in Critical Care

Australasian Journal of Ultrasound in Medicine, Volume 29, Issue 3, August 2026.
ABSTRACT Introduction/Purpose Point‐of‐care ultrasound (PoCUS) has evolved from bulky radiology‐based machines to a core bedside tool in critical care. Training processes have shifted from informal apprenticeship to structured curricula, yet challenges in standardisation, competence assessment and accreditation persist.
Arvind Rajamani, Pranav Arun Bharadwaj, Sriram Hariharan, Amritha Varshini Ragavan, Anwar Hassan, Hemamalini Arvind, Stephen Huang, on behalf of the SPARTAN Collaborative (Small Projects, Audits and Research Trials – Australia, New Zealand)   +9 more
wiley   +1 more source

Quality Assurance Framework for the Design, Collection and Curation of Standard Data Products From a Distributed Ecology Network

Ecology and Evolution, Volume 16, Issue 8, August 2026.
Ecological data are increasingly collected by networks of collaborators using replicated designs and methods, which can significantly improve the quality and quantity of data throughout the ecological niche and geographic range of species or communities.
Yvonne M. Buckley, Alain Finn, Aoife Molloy, Anna Mária Csergő, Elizabeth Crone, Annabel L. Smith, Bret D. Elderd, Caroline McKeon, Deborah Roach, Dylan Z. Childs, Glenda M. Wardle, María B. García, Maude Baudraz, Rachel M. Penczykowski, Roberto Salguero‐Gómez, Ruth Kelly, Satu Ramula, Anna Liisa Laine, Simone Blomberg, Johan Ehrlen, Jesús Villellas, Aveliina Helm, Christiane Roscher, Krista Raveala, Liv Norunn Hamre, Lotte Korell, Francis Q. Brearley, Siri Lie Olsen, Astrid Wingler, Joslin L. Moore, Ayco J. M. Tack, Anna Bucharova, Olav Skarpaas, Judit Bodis, Aldo Compagnoni, Sergi Munne‐Bosch, Zuzana Munzbergova, Joachim Töpper, Peter Vesk, Melanie Morales, Lizzie Wandrag, Marjo Saastamoinen, Martin Andrzejak, Pil Rasmussen, Christina Caruso, Richard Duncan, John Dwyer, Matthew Coghill, Ronny Groenteman, Meelis Pärtel, William K. Petry, Michele Lonati, Javier Puy, Jane Catford, Trevor H. Drees, Christoph Rosche, Katriona Shea, Simone Ravetto Enri, Jennifer R. Gremer, Balázs Deák, Lauchlan Fraser, Lauri Laanisto, Orsolya Valkó, Robert Drew Sieg, Benedicte Bachelot, Jennifer Firn   +65 more
wiley   +1 more source

Limited influence of nest site vegetation on female wild turkey survival during incubation

Ecosphere, Volume 17, Issue 8, August 2026.
Abstract Resource quality in heterogeneous environments directly underlies individual fitness. Gallinaceous birds, such as female eastern wild turkeys (Meleagris gallopavo silvestris), face significant reproductive challenges, particularly predation risk associated with ground nesting.
Nicholas W. Bakner, Allison C. Keever, Bret A. Collier, Michael J. Chamberlain, Bradley S. Cohen   +4 more
wiley   +1 more source

Il bardo dell’anedonia. Bret Easton Ellis e Imperial Bedrooms: un’intervista

Iperstoria, 2014
Il bardo dell’anedonia.
Valeria Gennero
doaj   +1 more source

Highly bright and stable NIR-BRET with blue-shifted coelenterazine derivatives for deep-tissue imaging of molecular events in vivo

Theranostics, 2019
Background: Bioluminescence imaging (BLI) is one of the most widely used optical platforms in molecular imaging, but it suffers from severe tissue attenuation and autoluminescence in vivo.
Ryo Nishihara, R. Paulmurugan, Takahiro Nakajima, Eiji Yamamoto, A. Natarajan, Rayhaneh Afjei, Y. Hiruta, N. Iwasawa, S. Nishiyama, D. Citterio, Moritoshi Sato, Sung Bae Kim, Koji Suzuki   +12 more
semanticscholar   +1 more source

Protocol to measure and analyze protein interactions in mammalian cells using bioluminescence resonance energy transfer

STAR Protocols
Summary: Bioluminescence resonance energy transfer (BRET) allows to quantitate protein interactions in intact cells. Here, we present a protocol for measuring BRET due to transient interactions of oncogenic K-RasG12V in plasma membrane nanoclusters of ...
Carla Jane Duval, Candy Laura Steffen, Karolina Pavic, Daniel Kwaku Abankwa   +3 more
doaj   +1 more source