Results 71 to 80 of about 39,288 (183)

Detection of the Vascular Endothelial Growth Factor with a Novel Bioluminescence Resonance Energy Transfer Pair Using a Two-Component System

Sensors, 2017
In this paper we describe a two-component BRET (bioluminescence resonance energy transfer)-based method to detect vascular endothelial growth factor (VEGF) molecules in unknown samples as the basis for subsequent in vivo use.
Tobias Wimmer, Eva Schroeter, Birgit Lorenz, Knut Stieger   +3 more
doaj   +1 more source

Colección de sermones de D. Bruno Bret

, 1883
Según Palau, 34955, solo se reimprimio el tomo VII que contiene: Novenario de almas, oraciones fúnebres y Sermones para ...
Bret, Bruno
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BRET-BASED BIOSENSORS TO DETECT VIRAL PROTEASES ACTIVITY IN CELLS

, 2022
reservedLe proteasi virali sono considerate un eccellente bersaglio per lo sviluppo di farmaci antivirali perché essenziali per la replicazione dei virus.
DJOSSOU, ATALIE VERRA-VICTORIA
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Systematic profiling reveals broad G protein coupling and context‐dependent modulation of cyclic AMP by the orphan receptor GPR139

British Journal of Pharmacology, EarlyView.
Background and Purpose G protein‐coupled receptors (GPCRs) are major drug targets, yet many orphan receptors remain poorly characterized. GPR139 has been implicated in CNS disorders, including schizophrenia and depression, but its signalling mechanisms remain unclear.
Boris Trapkov, Hans Bräuner, Alexander Sebastian Hauser   +2 more
wiley   +1 more source

Selective excitatory effects of γ‐glutamyl‐glycine, a glutathione metabolite, on GluN1 NMDA and mGlu5 receptors impacting synaptic plasticity

British Journal of Pharmacology, EarlyView.
Background and Purpose Gamma‐glutamyl dipeptides are essentially produced after glutathione (GSH) degradation. While several γ‐glutamyl dipeptides have been detected in different organs and body fluids, their biological activity remains elusive. This is the case for γ‐Glutamyl‐Glycine (γ‐Glu‐Gly) which has been found in different brain areas.
Sandro Andreu, Victoria Gizzi, Ugo Pasco, Fatiha Sebih, Yattou Zitouni, Pablo Jimenez, Valérie Rolland, Alain Chavanieu, Sébastien Estaran, Matthieu Rousset, Thierry Cens, Guillaume Cazals, Pierre Charnet, Janique Guiramand, Catherine Cohen‐Solal, Claudine Ménard, Marie‐Céleste de Jésus Ferreira, Nathalie Chevallier, Sonia Cantel, Michel Vignes, Julien Roussel   +20 more
wiley   +1 more source

Bret Harte: Prince and Pauper [PDF]

, 2016
Here Donna Campbell provides a review of Bret Harte: Prince and Pauper, a biography by Axel Nissen that considers the significance of Bret Harte, American short story writer (1836-1902)
Campbell, Donna
core   +4 more sources

Positive modulation of glucagon‐like peptide 1 (GLP‐1) receptor by endogenous haemorphins with implications in glucose metabolism and diabetes

British Journal of Pharmacology, EarlyView.
Haemorphins act on GLP‐1 receptor (GLP‐1R) activity and signalling in a positive allosteric manner. This leads to potentiated GLP‐1‐mediated activity and signalling, as well as insulin synthesis, which may have implications for glucose metabolism and, thereby, diabetes and obesity. (The graph was created in BioRender.com).
Farheen Badrealam Khan, Rwdah Mohamed Alameri, Yasir S. Raouf, Damien Maurel, Naiem Ahmad Wani, Anatoliy Shmygol, Irfa Anwar, Heng B. See, Elizabeth K. M. Johnstone, Elodie Dupuis, Eric Trinquet, Kevin D. G. Pfleger, Emilia Oueis, Mohammed Akli Ayoub   +13 more
wiley   +1 more source

Colección de sermones de D. Bruno Bret, Pbro. ...

, 1888
T.
Bret, Bruno
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Best Case/Worst Case: A Multisite Randomized Trial of Scenario Planning for Patients With Late‐Stage Kidney Disease

Journal of the American Geriatrics Society, EarlyView.
Best Case/Worst Case is a communication tool that uses scenario planning to support nephrologists and older adults with advanced chronic kidney disease as they make decisions about life with or without dialysis. ABSTRACT Background Best Case/Worst Case (BC/WC) is a communication tool to support nephrologists and older adults with advanced chronic ...
Lily N. Stalter, Bret M. Hanlon, Kyle J. Bushaw, Jenna Nitkowski, Anne Buffington, Katharine L. Cheung, Amy B. Zelenski, Kristine Kwekkeboom, Amar D. Bansal, Deidra Candice Crews, Holly M. Koncicki, Daniel Lam, Alvin H. Moss, Maya K. Rao, Dawn Felicity Wolfgram, Jeniann Yi, Carrie Brill, Tamara Isakova, Margaret L. Schwarze   +18 more
wiley   +1 more source

Differential Effects of Camel Milk on Insulin Receptor Signaling – Towards Understanding the Insulin-like Properties of Camel Milk

Frontiers in Endocrinology, 2016
Previous studies on the Arabian camel (Camelus dromedarius) showed beneficial effects of its milk reported in diverse models of human diseases including a substantial hypoglycemic activity.
Abdulrasheed O Abdulrahman, Mohammad A Ismael, Khaled A Alhosaini, Christelle eRame, Abdulrahman M Al-Senaidy, Joëlle eDupont, Mohammed Akli AYOUB, Mohammed Akli AYOUB, Mohammed Akli AYOUB   +8 more
doaj   +1 more source