Results 51 to 60 of about 131,173 (232)

Progress report on new epilepsy treatments: A summary of the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII). II. Treatments in more advanced clinical development

Epilepsia, EarlyView.
Abstract This article summarizes data for 13 investigational treatments for which at least preliminary seizure outcome data in patients with epilepsy were reported at the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices held in Madrid, Spain, on May 3–6, 2026.
Meir Bialer, Cecilie Johannessen Landmark, Matthias J. Koepp, Emilio Perucca, Piero Perucca, Torbjörn Tomson, H. Steve White, Elaine Wirrell   +7 more
wiley   +1 more source

DeepPatchNet: A deep learning model for enhanced screening and diagnosis of oral cancer

Informatics in Medicine Unlocked
Oral cancer remains a serious global health challenge, significantly affecting patient survival and quality of life. While convolutional neural networks (CNNs) have historically dominated image classification tasks, recent advances suggest that ...
Idriss Tafala, Fatima-Ezzahraa Ben-Bouazza, Aymane Edder, Oumaima Manchadi, Bassma Jioudi   +4 more
doaj   +1 more source

Setting up a Bioluminescence Resonance Energy Transfer high throughput screening assay to search for protein/protein interaction inhibitors in mammalian cells.

Frontiers in Endocrinology, 2012
Each step of the cell life and its response or adaptation to its environment are mediated by a network of protein/protein interactions termed interactome.
Cyril eCouturier, Benoit eDeprez
doaj   +1 more source

Changes in deer hunter satisfaction under special antlerless harvest regulations in Pennsylvania, USA

The Journal of Wildlife Management, EarlyView.
Deer Management Assistance Program hunter satisfaction in Pennsylvania increased over time and was associated with antlerless deer harvest success, repeated permit purchases, and seeing an antlerless deer. Understanding these relationships can help wildlife agencies support both deer management objectives and long‐term hunter engagement.
Arun Regmi, Duane R. Diefenbach, Jacob J. Trowbridge, Melissa M. Kreye, Kripa Neupane, Emily J. Domoto, Christopher S. Rosenberry, Bret D. Wallingford, David P. Stainbrook, Marc E. McDill, Patrick J. Drohan, Autumn E. Sabo   +11 more
wiley   +1 more source

Leveraging multilingual RAG for breast cancer RCPs: AI-driven speech transcription and compliance in Darija-French clinical discussions

Computer Methods and Programs in Biomedicine Update
The integration of artificial intelligence (AI) into clinical decision-making has introduced new opportunities for automating and enhancing medical documentation, particularly in oncology, where multidisciplinary meetings are central to treatment ...
Ilyass Emssaad, Fatima-Ezzahraa Ben-Bouazza, Idriss Tafala, Manal Chakour El Mezali, Bassma Jioudi   +4 more
doaj   +1 more source

Investigation of interactions between TLR2, MyD88 and TIRAP by bioluminescence resonance energy transfer is hampered by artefacts of protein overexpression. [PDF]

PLoS ONE, 2018
Toll like receptors (TLRs) are important pattern recognition receptors that can detect pathogen and danger associated molecular patterns to initiate an innate immune response.
Natália G Sampaio, Martina Kocan, Louis Schofield, Kevin D G Pfleger, Emily M Eriksson   +4 more
doaj   +1 more source

The Allais Paradox and Upside/Downside Risk Preference: An Experimental Analysis With Probability Weighting and Chernoff Faces

Southern Economic Journal, EarlyView.
ABSTRACT The Allais Paradox is often attributed to the strong attraction of a certain option that avoids a downside risk, i.e., a small chance of a low payoff. In contrast, there is clear evidence from laboratory and field data that people are attracted to the upside risk of obtaining a relatively high payoff.
Irene Comeig, Charles Holt
wiley   +1 more source

Live-Cell Analysis of Human Cytomegalovirus DNA Polymerase Holoenzyme Assembly by Resonance Energy Transfer Methods

Microorganisms, 2021
Human cytomegalovirus (HCMV) genome replication is a complex and still not completely understood process mediated by the highly coordinated interaction of host and viral products.
Veronica Di Antonio, Giorgio Palù, Gualtiero Alvisi   +2 more
doaj   +1 more source

Diagnostic antibodies at an inflection point: From discovery platforms to design‐oriented engineering

VIEW, EarlyView.
This study systematically organizes the evolution of diagnostic antibodies from discovery platforms to design‐oriented engineering and analyzes the strengths and limitations of each approach. Meanwhile, it provides a critical, literature‐driven synthesis of current challenges, proposing integrated strategies for assay‐aware and function‐driven antibody
Qitao Song, Lulai Xu, Weilin Wu, Fei Xie, Yantong Pan, Tiantian Yang, Xiaoxia Xu, Yanyin Lin, Lihua Zhang, Jiahui Zhou, Junyou Zhou, Linping Li, Zhanhui Wang, Weijing Yi, Jing Wang   +14 more
wiley   +1 more source

Bioluminescence Resonance Energy Transfer as a Method to Study Protein-Protein Interactions: Application to G Protein Coupled Receptor Biology

Molecules, 2019
The bioluminescence resonance energy transfer (BRET) approach involves resonance energy transfer between a light-emitting enzyme and fluorescent acceptors.
Chayma El Khamlichi, Flora Reverchon-Assadi, Nadège Hervouet-Coste, Lauren Blot, Eric Reiter, Séverine Morisset-Lopez   +5 more
doaj   +1 more source