Results 101 to 110 of about 18,515 (257)
Med14 cooperates with brg1 in the differentiation of skeletogenic neural crest [PDF]
BMC Developmental Biology, 2015 Abstract Background An intricate gene regulatory network drives neural crest migration and differentiation. How epigenetic regulators contribute to this process is just starting to be understood. Results We found that mutation of med14 or brg1 in zebrafish embryos resulted ...
Xin Lou +2 more
openaire +3 more sources
Frontiers in Cell and Developmental Biology, 2019 Trans-differentiation of endothelial cells to myofibroblast contributes to liver fibrosis. Reactive oxygen species (ROS) plays a key role in endothelial-mesenchymal transition (EndMT) although the underlying epigenetic mechanism is unclear.
Zilong Li +14 more
doaj +1 more source
DAF-16/FOXO employs the chromatin remodeller SWI/SNF to promote stress resistance and longevity [PDF]
, 2013 Organisms are constantly challenged by stresses and privations and require adaptive responses for their survival. The transcription factor DAF-16/FOXO is central nexus in these responses, but despite its importance little is known about how it regulates ...
Asara, John M. +10 more
core +1 more source
Analytic Formulations of the Density Matrix Renormalization Group
, 1995 We present two new analytic formulations of the Density Matrix Renormalization Group Method. In these formulations we combine the block renormalization group (BRG) procedure with Variational and Fokker-Planck methods. The BRG method is used to reduce the
Martin-Delgado, Miguel A. +1 more
core +2 more sources
TBL1 is required for the mesenchymal phenotype of transformed breast cancer cells [PDF]
, 2019 The epithelial-to-mesenchymal transition (EMT) and its reversion (MET) are related to tumor cell dissemination and migration, tumor circulating cell generation, cancer stem cells, chemoresistance, and metastasis formation.
García Martínez, Jorge +4 more
core +2 more sources
European Journal of Neuroscience, Volume 63, Issue 8, April 2026.Numerical cognition arises from conserved mechanisms linking genes, neural circuits and behaviour. Using zebrafish as a tractable model, behavioural assays, whole‐brain imaging and genetic analyses can be integrated to identify neural and molecular bases of quantity discrimination. This framework provides a platform for studying numerical cognition and
Mirko Zanon +3 more
wiley +1 more source
BRG1 in the Nucleus Accumbens Regulates Cocaine-Seeking Behavior [PDF]
Biological Psychiatry, 2016 Drug addiction is defined as a chronic disease characterized by compulsive drug seeking and episodes of relapse despite prolonged periods of drug abstinence. Neurobiological adaptations, including transcriptional and epigenetic alterations in the nucleus accumbens, are thought to contribute to this life-long disease state.
Zi-Jun, Wang +8 more
openaire +2 more sources
When R‐Loops Go Awry: Genome Instability and Neurological Diseases
European Journal of Neuroscience, Volume 63, Issue 8, April 2026.DNA normally exists as a double helix formed by two complementary strands. During gene transcription, however, one strand of DNA can bind to RNA, causing the other DNA strand to be displaced. This creates a structure called an R‐loop. R‐loops play important roles in normal cellular processes such as gene expression, DNA replication, and transcription ...
Nur Rasyiqin Rasli, Yu Katsuyama
wiley +1 more source
The Catalytic and Non-catalytic Functions of the Brahma Chromatin-Remodeling Protein Collaborate to Fine-Tune Circadian Transcription in Drosophila. [PDF]
, 2015 Daily rhythms in gene expression play a critical role in the progression of circadian clocks, and are under regulation by transcription factor binding, histone modifications, RNA polymerase II (RNAPII) recruitment and elongation, and post-transcriptional
Chiu, Joanna C +4 more
core +3 more sources
The FEBS Journal, Volume 293, Issue 8, Page 2159-2177, April 2026.Genetic rearrangements resulting in the expression of KMT2A fusion alleles can lead to dramatic transcriptional disturbances that contribute to the onset of acute leukaemias. Fortunately, menin inhibition has emerged as a promising new class of targeted therapy.
Lydia Elaine Roets +2 more
wiley +1 more source