Results 111 to 120 of about 18,515 (257)
Frontiers in Cell and Developmental Biology, 2020 Hepatocyte is a hub for cholesterol metabolism. Augmented synthesis of cholesterol in the liver is associated with hypercholesterolemia and contributes to the pathogenesis of a host of cardiovascular and metabolic diseases.
Zhiwen Fan +6 more
doaj +1 more source
RNA Regulatory Networks: Key Hubs in the Panorama of Cancer and Emerging Therapeutic Targets
MedComm, Volume 7, Issue 3, March 2026.RNA regulatory networks play a crucial role in the initiation and progression of cancer through various modes of RNA interactions. Notably, circulating RNAs have emerged as potential biomarkers, while targeted interventions in RNA regulatory networks facilitate precise therapeutic strategies. ABSTRACT Cancer is a global health challenge. The initiation
Xuan Yin +9 more
wiley +1 more source
MedComm, Volume 7, Issue 3, March 2026.Cancer remains the leading cause of mortality worldwide, and drug resistance further underscores the urgent need for innovative therapeutic strategies. Chromatin, a stable yet highly dynamic nucleoprotein complex, serves as the primary carrier of genetic material in eukaryotic cells.
Wentao Xia +4 more
wiley +1 more source
Brg1 and RUNX1 synergy in regulating TRPM4 channel in mouse cardiomyocytes
Frontiers in PharmacologyBackgroundTransient Receptor Potential Melastatin 4 (TRPM4), a non-selective cation channel, plays a critical role in cardiac conduction abnormalities. Brg1, an ATP-dependent chromatin remodeler, is essential for regulating gene expression in both heart ...
Tao Ban +20 more
doaj +1 more source
A 5‐month‐old infant with a pineal tumor
Brain Pathology, Volume 36, Issue 3, May 2026.
Fabien Forest +7 more
wiley +1 more source
RETRACTED: The Chromatin-Remodeling Complex WINAC Targets a Nuclear Receptor to Promoters and Is Impaired in Williams Syndrome [PDF]
, 2003 This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy).This article has been retracted at the request of the Authors.Our paper reported that a chromatin-remodeling complex ...
Kitagawa, Hirochika +16 more
core +1 more source
Impact of SDN Controllers Deployment on Network Availability
, 2016 Software-defined networking (SDN) promises to improve the programmability and flexibility of networks, but it may bring also new challenges that need to be explored.
Gonzalez, Andres J. +4 more
core
Understanding the role of chromatin remodeling in the regulation of circadian transcription in Drosophila. [PDF]
, 2015 Circadian clocks enable organisms to anticipate daily changes in the environment and coordinate temporal rhythms in physiology and behavior with the 24-h day-night cycle. The robust cycling of circadian gene expression is critical for proper timekeeping,
Chiu, Joanna C +2 more
core +1 more source
Journal of Cellular and Molecular MedicineABSTRACTBRG1 and BRM are subunits of the SWI/SNF chromatin remodelling complex, which has DNA‐stimulated ATPase activity and can destabilise histone–DNA interactions. Targeting SWI/SNF is beneficial for treating various tumours, including glioblastoma (GBM). Our research focussed on BRG1 due to its overexpression in GBM.
Yinan Wang +7 more
openaire +2 more sources
SMARCA4/BRG1–Deficient Non–Small Cell Lung Carcinomas: A Case Series and Review of the Literature [PDF]
, 2020 Aruna Nambirajan +5 more
openalex +1 more source