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The BRG1 and the Actin Filament System
2006The DNA in eukaryotic cells is organized with proteins into chromatin. The chromatin structure is dynamic, altered when factors that use DNA as a template need access or to silence regions of the chromosome. The alteration of the chromatin structure is primarily the responsibility of ATP‐dependent chromatin‐remodeling complexes and histone‐modifying ...
Ann‐Kristin Östlund Farrants +2 more
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Chromatin remodelling by the glucocorticoid receptor requires the BRG1 complex
Nature, 1998The assembly of transcriptional regulatory DNA sequences into chromatin plays a fundamental role in modulating gene expression. The promoter of the mouse mammary-tumour virus (MMTV) is packaged into a regular array of nucleosomes when it becomes stably integrated into mammalian chromosomes, and has been used to investigate the relationship between ...
C J, Fryer, T K, Archer
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The Biological Significance of BRG1 Mutations
2006Eukaryotic organisms package DNA into chromatin for compact storage in the cell nucleus, but this packaging process results in transcriptional repression of genes. Chromatin remodeling complexes have evolved to overcome the transcriptional repression caused by chromatin packaging of DNA into nucleosomes by histones.
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Brg1 in heart disease: Friend or foe?
International Journal of Cardiology, 2022Xuesong, Zhang, Ying, Xia, Bin, Wang
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BRG1 in cancer: An insufficiently explored and controversial research area
Digestive and Liver Disease, 2022Jing, Zhang +3 more
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Apical role for BRG1 in cytokine-induced promoter assembly
Proceedings of the National Academy of Sciences of the United States of America, 2005David S Park +2 more
exaly