Results 251 to 260 of about 33,910 (293)

Corrigendum: Transient proteolysis reduction of <i>Nicotiana benthamiana</i>-produced CAP256 broadly neutralizing antibodies using CRISPR/Cas9. [PDF]

Front Plant Sci
Singh AA, Pillay P, Naicker P, Alexandre K, Malatji K, Mach L, Steinkellner H, Vorster J, Chikwamba R, Tsekoa TL.   +9 more
europepmc   +1 more source

Clinical and Laboratory Characterization of Acquired Von Willebrand Syndrome

American Journal of Hematology, EarlyView.
ABSTRACT Acquired von Willebrand Syndrome (AVWS) is a rare bleeding disorder characterized by quantitative or qualitative defects of von Willebrand factor (VWF) in patients without a personal or family history of bleeding. It is frequently associated with systemic diseases, particularly lymphoproliferative disorders (LPDs) and myeloproliferative ...
Alessandro Ciavarella, Luciano Baronciani, Omid Seidizadeh, Paola Colpani, Elio Ingenito, Daniele Cattaneo, Maria Teresa Pagliari, Addolorata Truma, Alessandra Iurlo, Simona Maria Siboni, Flora Peyvandi   +10 more
wiley   +1 more source

Design clues from functional constraints and broadly neutralizing antibodies

Retrovirology, 2006
Dimitrov Dimiter S, Burton Dennis R, Arthos James, Zwick Michael B, Zhang Mei-Yun, Yang Xinzhen, Xiang Shi-Hua, Van Ryk Donald, Majeed Shahzad, Hessell Ann J, Dey Barna, Xu Ling, Zhou Tongqing, Sodroski Joseph, Wyatt Richard, Nabel Gary J, Kwong Peter D   +16 more
doaj   +1 more source

Broadly neutralizing antibodies isolated from HEV convalescents confer protective effects in human liver-chimeric mice. [PDF]

Nat Commun
Ssebyatika G, Dinkelborg K, Ströh LJ, Hinte F, Corneillie L, Hueffner L, Guzman EM, Nankya PL, Plückebaum N, Fehlau L, Garn J, Meyer N, Prallet S, Mehnert AK, Kraft ARM, Verhoye L, Jacobsen C, Steinmann E, Wedemeyer H, Viejo-Borbolla A, Dao Thi VL, Pietschmann T, Lütgehetmann M, Meuleman P, Dandri M, Krey T, Behrendt P.   +26 more
europepmc   +1 more source

Molecular mechanism of ischemic postconditioning in promoting diabetic ischemic brain injury repair via the microRNA‐34a–BDNF–SIX3 signaling axis

Animal Models and Experimental Medicine, EarlyView.
Diabetes combined with ischemic stroke (DMIS) exacerbates brain infarct size and neuronal damage compared to nondiabetic ischemic stroke (IS). This study reveals that microRNA‐34a (miR‐34a) plays a key role in DMIS pathogenesis: miR‐34a directly targets and suppresses brain‐derived neurotrophic factor (BDNF) and Sine oculis homeobox 3 (SIX3), promoting
Ling Zhao, Chunlan Zou, Junxian Li, Yang Yang, Yuanyuan Han, Tingyu Ke   +5 more
wiley   +1 more source

Distinct region-specific neutralization profiles of contemporary HIV-1 clade C against best-in-class broadly neutralizing antibodies. [PDF]

J Virol
Sutar J, Jayal P, Mullick R, Chaudhary S, Kamble P, Bhowmick S, Kaginkar S, Padwal V, Devadiga P, Neman N, Kitchin D, Kaldine H, Mkhize NN, Ndlovu B, Gounder K, Mukherjee S, Shrivas S, Sharma N, Prasad C, Tewatia S, Parihar N, Kumar N, Kasarpalkar N, Singh B, Mohapatra S, Aquil M, Kumar CV, Dinesha TR, Srikrishnan AK, Shastri J, Agrawal S, Gaikwad S, Mondal S, Bandyopadhyay B, Guha SK, Kale D, Biswas D, Patil D, Paranjape RS, Mukhopadhyay S, Hema, Das R, Kondapi A, Bhor V, Deshpande S, Sok D, Ndung'u T, Moore PL, Murugavel KG, Patel V, Bhattacharya J.   +50 more
europepmc   +1 more source

Hyperacute Interleukin‐1β Production and Neutrophil Extracellular Trap Formation in the Cerebral Circulation of Stroke Patients with Large Vessel Occlusion

Annals of Neurology, EarlyView.
Acute ischemic stroke due to large vessel occlusion is associated with rapid intravascular immune activation. Analysis of arterial blood sampled distal to the thrombus during mechanical thrombectomy revealed increased extracellular adenosine triphosphate (ATP) and interleukin‐1β (IL‐1β) levels, evidence of inflammasome priming in monocytes, and ...
Justine Münsterberg, Caspar Brekenfeld, Hanna Englert, Marius Piepke, Regine J. Dress, Martin Oertel, Tina Fischer, Romy Hackbusch, Mingming Zha, Haodi Cai, Christian Casar, Ines S. Schädlich, Leo Winter, Alina Jander, Karoline Degenhardt, Maxim Bester, Fabian Flottmann, Uta Hanning, Brigitte Holst, Anna Worthman, Johanna Hiefner, Berenike Rutz, Eckhard Schlemm, Götz Thomalla, Bettina H. Clausen, Ann M. Stowe, Immo Prinz, Thiruma V. Arumugam, Markus Glatzel, Thomas Renné, Jens Fiehler, Eva Tolosa, Tim Magnus, Mathias Gelderblom   +33 more
wiley   +1 more source

Acceptability of broadly neutralizing antibodies (bNAbs) for HIV prevention among vulnerable populations in India: Findings from a qualitative study. [PDF]

PLoS One
Mukherjee J, Ul Hadi S, Chakrapani V, Rawat S, Srikrishnan AK, Mahendra V, Baruah D, Mohapatra S, Gopinath U, Dange A, Rath P, Manchi P, Gangaramany A, Aggarwal P, Malhotra S, Keane M, Goyal R.   +16 more
europepmc   +1 more source

Spatial Cell Death and Oxidative Stress Dynamics in Gas Plasma‐Treated Tumor Tissues

Advanced NanoBiomed Research, EarlyView.
Schematic representation of the four experimental models to study tissue penetration and oxidation. Four tissue models were used. Human pancreatic cancer cells were grown on the chorioallantois membrane of chicken embryos and gas plasma‐treated in ovo, murine colorectal tumor tissue was gas plasma‐exposed ex vivo, murine squamous cell carcinoma cells ...
Anke Schmidt, Shahrzad Rokhsary, Linus Hübner, Lea Miebach, Sander Bekeschus   +4 more
wiley   +1 more source

Discovery and characterization of potent broadly neutralizing antibodies from human survivors of severe fever with thrombocytopenia syndrome. [PDF]

EBioMedicine
Zhang S, Shang H, Han S, Li J, Peng X, Wu Y, Yang X, Leng Y, Wang F, Cui N, Xu L, Zhang H, Guo Y, Xu X, Zhang N, Liu W, Li H.   +16 more
europepmc   +1 more source