Results 261 to 270 of about 33,910 (293)

Cold Gas Plasma Induces Platelet Activation and Hemostasis in Native and Anticoagulated Human Blood

Advanced NanoBiomed Research, EarlyView.
Cold physical gas plasma induces platelet activation and hemostatic responses in native and anticoagulated human blood. Treatment efficacy depends on plasma parameters, including gas composition, distance, and exposure mode, which govern reactive species delivery and energy transfer.
Sander Bekeschus, Broder Poschkamp, Lea Miebach, Anke Schmidt, Linus Hübner, Julia van der Linde   +5 more
wiley   +1 more source

Epitope-focused immunogens targeting the hepatitis C virus glycoproteins induce broadly neutralizing antibodies. [PDF]

Sci Adv
Nagarathinam K, Scheck A, Labuhn M, Ströh LJ, Herold E, Veselkova B, Tune S, Cramer JT, Rosset S, Vollers SS, Bankwitz D, Ballmaier M, Böning H, Roth E, Khera T, Ahsendorf-Abidi HP, Dittrich-Breiholz O, Obleser J, Nassal M, Jäck HM, Pietschmann T, Correia BE, Krey T.   +22 more
europepmc   +1 more source

The Use of Broadly Neutralizing Antibodies (bNAbs) in HIV-1 Treatment and Prevention. [PDF]

Viruses
Thavarajah JJ, Hønge BL, Wejse CM.
europepmc   +1 more source

Potent broadly neutralizing antibodies mediate efficient antibody-dependent phagocytosis of HIV-infected cells. [PDF]

PLoS Pathog
Snow BJ, Keles NK, Grunst MW, Janaka SK, Behrens RT, Evans DT.   +5 more
europepmc   +1 more source

Affinity maturation endows potent activity onto class 6 SARS-CoV-2 broadly neutralizing antibodies. [PDF]

Proc Natl Acad Sci U S A
Mazigi O, Langley DB, Henry JY, Burnett DL, Sobti M, Walker GJ, Rouet R, Balachandran H, Lenthall H, Jackson J, Ubiparipovic S, Schofield P, Brown SHJ, Schulz SR, Hoffmann M, Pöhlmann S, Post J, Martinello M, Ahlenstiel G, Kelleher A, Rawlinson WD, Turville SG, Bull RA, Stewart AG, Jäck HM, Goodnow CC, Christ D.   +26 more
europepmc   +1 more source

Broadly neutralizing antibodies to prevent HIV-1

Science, 2017
Studies show the potential of synthetic and combinations of broadly neutralizing ...
Myron S, Cohen, Lawrence, Corey
core   +5 more sources

In vivo protection by broadly neutralizing HIV antibodies

Trends in Microbiology, 2014
Passive immunization studies, including a recent one by Pegu et al., have repeatedly shown that HIV-specific broadly neutralizing antibodies (bnAbs) protect rhesus macaques from HIV acquisition. In vitro neutralization potency and in vivo protection correlate very strongly, supporting the quest for an HIV vaccine that induces potent bnAbs.
Marit J. van Gils, Rogier W. Sanders
openaire   +3 more sources

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A recipe for inducing broadly neutralizing antibodies

Nature Reviews Immunology, 2016
An immune profile associated with the production of broadly neutralizing antibodies is identified in HIV-1-infected individuals.
exaly   +3 more sources

Broadly Neutralizing Antibodies for HIV Prevention

Annual Review of Medicine, 2020
In the last decade, over a dozen potent broadly neutralizing antibodies (bnAbs) to several HIV envelope protein epitopes have been identified, and their in vitro neutralization profiles have been defined. Many have demonstrated prevention efficacy in preclinical trials and favorable safety and pharmacokinetic profiles in early human clinical trials ...
Shelly T, Karuna, Lawrence, Corey
openaire   +2 more sources

Broadly Neutralizing Antiviral Antibodies

Annual Review of Immunology, 2013
A fascinating aspect of viral evolution relates to the ability of viruses to escape the adaptive immune response. The widely held view has been that the great variability of viral glycoproteins would be an absolute obstacle to the development of antibody-based therapies or vaccines that could confer broad and long-lasting protection.
Corti D., Lanzavecchia A.
openaire   +3 more sources