Results 71 to 80 of about 32,014 (200)

Airway dysfunction in elite swimmers: prevalence, impact, and challenges

Open Access Journal of Sports Medicine, 2016
Mitch Lomax Department of Sport and Exercise Science, University of Portsmouth, Portsmouth, UK Abstract: The prevalence of airway dysfunction in elite swimmers is among the highest in elite athletes. The traditional view that swimmers naturally gravitate
Lomax M
doaj  

Broncoespasmo induzido por exercício em corredores brasileiros de longa distância de elite Exercise-induced bronchoconstriction in elite long-distance runners in Brazil

Jornal Brasileiro de Pneumologia, 2012
OBJETIVO: Determinar a prevalência de broncoespasmo induzido por exercício em corredores brasileiros de longa distância de elite e se há uma diferença na carga de treinamento entre atletas com e sem broncoespasmo induzido por exercício.
Renata Nakata Teixeira, Luzimar Raimundo Teixeira, Luiz Augusto Riani Costa, Milton Arruda Martins, Timothy Derick Mickleborough, Celso Ricardo Fernandes Carvalho   +5 more
doaj   +1 more source

Safety, tolerability, pharmacokinetics and pharmacodynamics of the spleen tyrosine kinase inhibitor BI 894416 in healthy volunteers and patients with asthma

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Spleen tyrosine kinase (SYK) has broad biological functions in inflammation and immunity. The orally administered SYK inhibitor BI 894416 was investigated in a single‐rising‐dose Phase I study in healthy volunteers and in a combined single‐ and multiple‐rising‐dose Phase Ib study in patients with mild asthma ...
Saskia Carstensen‐Aurèche, Tobias Litzenburger, Dorothy De Sousa, Reinhard Sailer, Ewald Benediktus, Denis Delic, Fabian Müller, Meike Müller, Jens M. Hohlfeld   +8 more
wiley   +1 more source

Neurally mediated airway constriction in human and other species: a comparative study using precision-cut lung slices (PCLS). [PDF]

PLoS ONE, 2012
The peripheral airway innervation of the lower respiratory tract of mammals is not completely functionally characterized. Recently, we have shown in rats that precision-cut lung slices (PCLS) respond to electric field stimulation (EFS) and provide a ...
Marco Schlepütz, Annette D Rieg, Sophie Seehase, Jan Spillner, Alberto Perez-Bouza, Till Braunschweig, Thomas Schroeder, Marc Bernau, Verena Lambermont, Christina Schlumbohm, Katherina Sewald, Rüdiger Autschbach, Armin Braun, Boris W Kramer, Stefan Uhlig, Christian Martin   +15 more
doaj   +1 more source

気管支喘息患者における白血球ロイコトリエン産生能に対する不飽和脂肪酸食の効果に影響する因子 [PDF]

, 1999
Dietary supplementation with perilla seed oil, a vegetable oil rich in α -lin- olenic acid, inhibits the generation of leukotrienes(LTs) by leucocytes in patients with bronchial asthma. We examined the factors that affect the suppression of LT generation
Ashida, Kozo, Harada, Mine, Harada, Seishi, Hosaki, Yasuhiro, Kataoka, Mikio, Mifune, Takashi, Mitsunobu, Fumihiro, Niiya, Kenji, Okamoto, Makoto, Takada, Shingo, Tanizaki, Yoshiro, Tsugeno, Hirofumi   +11 more
core   +1 more source

AllergoOncology in Review: Harnessing Allergy in the Field of Oncology to Improve Patient Outcomes

Clinical &Experimental Allergy, EarlyView.
ABSTRACT The AllergoOncology field brings together the study of allergic and cancer immune responses, having evolved from early epidemiological studies that reported inverse associations between allergies, IgE and cancer risk. Insights from studying allergic inflammation are revealing previously unappreciated immune mechanisms that confer protective ...
Jakub Zydron, Anishaa Balaji, Jitesh Chauhan, Jack Alder, Xinyi Chen, Anna M. F. Wiegman, Aurelie Poli, Joanna Jacków‐Malinowska, Jack Cheeseman, Daniel I. R. Spencer, James McDonnell, James Spicer, Alexandra J. McCraw, Sophia N. Karagiannis   +13 more
wiley   +1 more source

Factors Associated with Poor Asthma Control among Sudanese Patients Attending Atbara Teaching Hospital in Sudan

Sudan Journal of Medical Sciences
Objective: To identify factors associated with poor bronchial asthma control in patients attending Atbara Teaching Hospital, Sudan, in 2020. Methods: This was an analytical, descriptive, cross-sectional hospital-based study conducted at the Atbara ...
Hadeel Kareem Aladdin, Sufian Khalid Mohammed Noor, Amro Mohamed Fagir Farah, Sara Elamin Bushara   +3 more
doaj   +1 more source

Paradoxical bronchoconstriction caused by β2-adrenoceptor agonists

Drug Target Insights, 2020
Introduction: Salbutamol and terbutaline are short-acting β2 adrenergic agonists that produce bronchial smooth muscle relaxation and are widely used in obstructive pulmonary diseases.
Khadija Ayed, Islam Latifa Hadi Khalifa, Salma Mokaddem, Saloua Ben Khamsa Jameleddine   +3 more
doaj   +1 more source

Regulation of eosinophilia and allergic airway inflammation by the glycan-binding protein galectin-1 [PDF]

, 2016
Galectin-1 (Gal-1), a glycan-binding protein with broad antiinflammatory activities, functions as a proresolving mediator in autoimmune and chronic inflammatory disorders. However, its role in allergic airway inflammation has not yet been elucidated.
Abramoff, Ada G. Blidner, Amrita Rao, Boehme, Gabriel A. Rabinovich, Ge, Ha, He, Idil Bastan, Matsuura, P. Sriramarao, Rabinovich, Savita P. Rao, Sung Gil Ha, Xiao Na Ge, Yana G. Greenberg   +15 more
core   +1 more source

Amitriptyline inhibits bronchoconstriction and directly promotes dilatation of the airways

Respiratory Research, 2023
Introduction The standard therapy for bronchial asthma consists of combinations of acute (short-acting ß2-sympathomimetics) and, depending on the severity of disease, additional long-term treatment (including inhaled glucocorticoids, long-acting ß2 ...
Paulina Hempel, Virag Klein, Anna Michely, Svenja Böll, Annette D. Rieg, Jan Spillner, Till Braunschweig, Saskia von Stillfried, Norbert Wagner, Christian Martin, Klaus Tenbrock, Eva Verjans   +11 more
doaj   +1 more source