Results 21 to 30 of about 61,454 (303)

The short-term bronchodilator effects of the dual phosphodiesterase 3 and 4 inhibitor RPL554 in COPD

European Respiratory Journal, 2018
We investigated the short-term bronchodilator effects of RPL554 (an inhaled dual phosphodiesterase 3 and 4 inhibitor) combined with other bronchodilators in chronic obstructive pulmonary disease patients with reversibility (>150 mL to short-acting ...
Dave Singh, K. Abbott-Banner, T. Bengtsson, K. Newman   +3 more
semanticscholar   +1 more source

Pharmacological Validation for the Folklore Use of Ipomoea nil against Asthma: In Vivo and In Vitro Evaluation

Molecules, 2022
Oxidative stress is the key factor that strengthens free radical generation which stimulates lung inflammation. The aim was to explore antioxidant, bronchodilatory along with anti-asthmatic potential of folkloric plants and the aqueous methanolic crude ...
Taha Alqahtani, Sajida Parveen, Yahia Alghazwani, Hanan M. Alharbi, Reem M. Gahtani, Nadia Hussain, Kashif ur Rehman, Musaddique Hussain   +7 more
doaj   +1 more source

Triple Therapy of Fluticasone Furoate, Umeclidinium, Vilanterol- A Compelling Choice in Severe Chronic Obstructive Pulmonary Disease [PDF]

Journal of Clinical and Diagnostic Research, 2021
Trelegy Ellipta (GlaxoSmithKlineTM) is the first single inhaler triple combination therapy comprising of umeclidinium, vilanterol and fluticasone approved by the United States Food and Drug Administration (US FDA) for patients with severe COPD in 2019.
B Jagan Nathan, Melina I Sahay, AK Gautham, DK Sriram, Melvin George   +4 more
doaj   +1 more source

Something Is Changing in Viral Infant Bronchiolitis Approach

Frontiers in Pediatrics, 2022
Acute Viral Bronchiolitis is one of the leading causes of hospitalization in the first 12–24 months of life. International guidelines on the management of bronchiolitis broadly agree in recommending a minimal therapeutic approach, not recommending the ...
Paolo Bottau, Lucia Liotti, Eleonora Laderchi, Alessandra Palpacelli, Elisabetta Calamelli, Carlotta Colombo, Laura Serra, Salvatore Cazzato   +7 more
doaj   +1 more source

Cardiac arrhythmias in patients with bronchial asthma

Медицинский совет, 2022
Introduction. According to modern data, bronchial asthma (BA) is an independent risk factor for the development of cardiac arrhythmias (CA), and the use of long-acting β2-agonists (LABA) in basic therapy may further increase the risks of CA.Aim. To study
O. M. Uryasev, A. V. Shakhanov, I. Yu. Sudakova, L. V. Korshunova, V. P. Sidorova   +4 more
doaj   +1 more source

Tidal breathing parameters measured using structured light plethysmography in healthy children and those with asthma before and after bronchodilator

Physiological Reports, 2017
Structured light plethysmography (SLP) is a light‐based, noncontact technique that measures tidal breathing by monitoring displacements of the thoracoabdominal (TA) wall.
Hamzah Hmeidi, Shayan Motamedi-Fakhr, E. Chadwick, F. Gilchrist, W. Lenney, R. Iles, Rachel C. Wilson, J. Alexander   +7 more
semanticscholar   +1 more source

Effects of long-term bronchodilators in bronchiectasis patients with airflow limitation based on bronchodilator response at baseline

International Journal of COPD, 2016
Purpose The association between positive bronchodilator response (BDR) at baseline and the effect of long-term bronchodilator therapy has not been well elucidated in patients with bronchiectasis.
H. Jeong, Hyun Lee, K. Carriere, Jung Hoon Kim, Jinwook Han, Beomsu Shin, Byeong-Ho Jeong, W. Koh, O. Kwon, H. Park   +9 more
semanticscholar   +1 more source

Early COPD patients with lung hyperinflation associated with poorer lung function but better bronchodilator responsiveness

International Journal of COPD, 2016
Background It is unknown whether aggressive medication strategies should be used for early COPD with or without lung hyperinflation. We aimed to explore the characteristics and bronchodilator responsiveness of early COPD patients (stages I and II) with ...
Chunlan Chen, W. Jian, Yi Gao, Yan‐qing Xie, Yan Song, Jinping Zheng   +5 more
semanticscholar   +1 more source

Influenza A virus infection and cigarette smoke impair bronchodilator responsiveness to β-adrenoceptor agonists in mouse lung

Clinical science, 2016
The present study has shown that the bronchodilator effectiveness of β-adrenoceptor agonists is diminished in CS and influenza A virus-induced lung disease and has identified the need for the development of novel bronchodilators for these diseases.
C. Donovan, H. Seow, J. Bourke, R. Vlahos   +3 more
semanticscholar   +1 more source

A study of correlation between body mass index and GOLD staging of chronic obstructive pulmonary disease patients

The Journal of Association of Chest Physicians, 2013
Background: The association between low body mass index (BMI) and poor prognosis of patients with chronic obstructive pulmonary disease (COPD) is a common clinical observation and it varies with different stages of COPD. Aims: To find out any correlation
Mrinmoy Mitra, Santanu Ghosh, Kaushik Saha, Arnab Saha, Prabodh Panchadhyayee, Anirban Biswas, Tarasankar Malik, Arnab Roy, Pratik Barma   +8 more
doaj   +1 more source