Results 21 to 30 of about 60,500 (292)

Longitudinal FEV1 and Exacerbation Risk in COPD: Quantifying the Association Using Joint Modelling

open access: yesInternational Journal of COPD, 2021
Kirill Zhudenkov,1 Robert Palmér,2 Alexandra Jauhiainen,3 Gabriel Helmlinger,4,5 Oleg Stepanov,1 Kirill Peskov,1,6 Ulf G Eriksson,2 Ulrika Wählby Hamrén2 1M&S Decisions LLC, Moscow, Russia; 2Clinical Pharmacology & Quantitative
Zhudenkov K   +7 more
doaj  

Pharmacological Validation for the Folklore Use of Ipomoea nil against Asthma: In Vivo and In Vitro Evaluation

open access: yesMolecules, 2022
Oxidative stress is the key factor that strengthens free radical generation which stimulates lung inflammation. The aim was to explore antioxidant, bronchodilatory along with anti-asthmatic potential of folkloric plants and the aqueous methanolic crude ...
Taha Alqahtani   +7 more
doaj   +1 more source

The short-term bronchodilator effects of the dual phosphodiesterase 3 and 4 inhibitor RPL554 in COPD

open access: yesEuropean Respiratory Journal, 2018
We investigated the short-term bronchodilator effects of RPL554 (an inhaled dual phosphodiesterase 3 and 4 inhibitor) combined with other bronchodilators in chronic obstructive pulmonary disease patients with reversibility (>150 mL to short-acting ...
Dave Singh   +3 more
semanticscholar   +1 more source

Pharmacological Modulation of Endotoxin-Induced Release of IL-26 in Human Primary Lung Fibroblasts

open access: yesFrontiers in Pharmacology, 2019
Background: Interleukin (IL)-26 is a neutrophil-mobilizing and bactericidal cytokine that is enhanced in human airways in vivo in response to endotoxin from Gram-negative bacteria.
Karlhans Fru Che   +4 more
doaj   +1 more source

Possible Mechanisms Underlying the Antispasmodic, Bronchodilator, and Antidiarrheal Activities of Polarity–Based Extracts of Cucumis sativus L. Seeds in In Silico, In Vitro, and In Vivo Studies

open access: yesPharmaceuticals, 2022
Apart from the nutritional value, Cucumis sativus L. has also been used in the traditional medicine of Iran, Pakistan, and India. Its seeds are used by herbalists to treat gastrointestinal, respiratory, and urinary problems.
Muqeet Wahid   +5 more
doaj   +1 more source

Clinical Implications of the New Criteria for a Positive Bronchodilator Response in Children With Asthma. [PDF]

open access: yesActa Paediatr
Acta Paediatrica, Volume 114, Issue 7, Page 1731-1733, July 2025.
Stridsman C   +7 more
europepmc   +2 more sources

Something Is Changing in Viral Infant Bronchiolitis Approach

open access: yesFrontiers in Pediatrics, 2022
Acute Viral Bronchiolitis is one of the leading causes of hospitalization in the first 12–24 months of life. International guidelines on the management of bronchiolitis broadly agree in recommending a minimal therapeutic approach, not recommending the ...
Paolo Bottau   +7 more
doaj   +1 more source

Regional lung response to bronchodilator reversibility testing determined by electrical impedance tomography in chronic obstructive pulmonary disease.

open access: yesAmerican Journal of Physiology - Lung cellular and Molecular Physiology, 2016
Patients with obstructive lung diseases commonly undergo bronchodilator reversibility testing during examination of their pulmonary function by spirometry. A positive response is defined by an increase in forced expiratory volume in 1 s (FEV1). FEV1 is a
B. Vogt   +4 more
semanticscholar   +1 more source

Analysis of Asthma-Chronic Obstructive Pulmonary Disease Overlap Syndrome Defined on the Basis of Bronchodilator Response and Degree of Emphysema.

open access: yesAnnals of the American Thoracic Society, 2016
RATIONALE Despite the increasing recognition of asthma-chronic obstructive pulmonary disease overlap syndrome (ACOS) as a clinical entity, it remains poorly characterized due to a lack of agreement on its definition and diagnostic criteria.
James Cosentino   +6 more
semanticscholar   +1 more source

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