Results 21 to 30 of about 82,057 (334)

COPD: maximization of bronchodilation [PDF]

Multidisciplinary Respiratory Medicine, 2014
The most recent guidelines define COPD in a multidimensional way, nevertheless the diagnosis is still linked to the limitation of airflow, usually measured by the reduction in the FEV1/FVC ratio below 70%. However, the severity of obstruction is not directly correlated to symptoms or to invalidity determined by COPD.
Stefano Nardini, CAMICIOTTOLI, GIANNA, Salvatore Locicero, Rosario Maselli, Franco Pasqua, Giovanni Passalacqua, Riccardo Pela, Alberto Pesci, Alfredo Sebastiani, Alessandro Vatrella   +9 more
openaire   +7 more sources

Bronchodilator reversibility in asthma and COPD: findings from three large population studies

European Respiratory Journal, 2019
Bronchodilator response (BDR) testing is used as a diagnostic method in obstructive airway diseases. The aim of this investigation was to compare different methods for measuring BDR in participants with asthma and chronic obstructive pulmonary disease ...
C. Janson, C. Janson, A. Malinovschi, A. Amaral, S. Accordini, J. Bousquet, A. Buist, G. Canonica, B. Dahlén, J. Garcia-Aymerich, J. Garcia-Aymerich, L. Gnatiuc, M. Kowalski, J. Patel, W. Tan, K. Torén, T. Zuberbier, P. Burney, D. Jarvis   +18 more
semanticscholar   +1 more source

Triple therapy versus single and dual long-acting bronchodilator therapy in COPD: a systematic review and meta-analysis

European Respiratory Journal, 2018
We performed a meta-analysis to compare the impact of triple combination therapy with inhaled corticosteroids (ICS), long-acting β2-agonists (LABAs) and long-acting muscarinic receptor antagonists (LAMAs) versus LABA/LAMA combination therapy or single ...
M. Cazzola, P. Rogliani, L. Calzetta, M. Matera   +3 more
semanticscholar   +1 more source

Clinical significance of the bronchodilator response in children with severe asthma

Pediatric Pulmonology, 2019
Our objective was to determine those characteristics associated with reversibility of airflow obstruction and response to maximal bronchodilation in children with severe asthma through the Severe Asthma Research Program (SARP).
A. Coverstone, L. Bacharier, Bradley S Wilson, Anne M. Fitzpatrick, W. G. Teague, Wanda Phipatanakul, S. Wenzel, B. Gaston, E. Bleecker, Wendy C Moore, Sima K. Ramratnam, Nizar Jarjour, Ngoc P Ly, John V Fahy, D. Mauger, Kenneth B Schechtman, Huiqing Yin-Declue, J. Boomer, Mario Castro   +18 more
semanticscholar   +1 more source

Pharmacological Validation for the Folklore Use of Ipomoea nil against Asthma: In Vivo and In Vitro Evaluation

Molecules, 2022
Oxidative stress is the key factor that strengthens free radical generation which stimulates lung inflammation. The aim was to explore antioxidant, bronchodilatory along with anti-asthmatic potential of folkloric plants and the aqueous methanolic crude ...
Taha Alqahtani, Sajida Parveen, Yahia Alghazwani, Hanan M. Alharbi, Reem M. Gahtani, Nadia Hussain, Kashif ur Rehman, Musaddique Hussain   +7 more
doaj   +1 more source

Caffeine for asthma [PDF]

, 2010
Background Caffeine has a variety of pharmacological effects; it is a weak bronchodilator and it also reduces respiratory muscle fatigue. It is chemically related to the drug theophylline which is used to treat asthma.
Becker, Bruce, Bukowskyj, Cheney, Colacone, Crivelli, Curatolo, Duffy, Gong, Grollman, Henderson, Kivity, Pagano, Robertson, Simmons, Stephenson, Taylor, Taylor, Woodcock, Yurach   +19 more
core   +1 more source

The short-term bronchodilator effects of the dual phosphodiesterase 3 and 4 inhibitor RPL554 in COPD

European Respiratory Journal, 2018
We investigated the short-term bronchodilator effects of RPL554 (an inhaled dual phosphodiesterase 3 and 4 inhibitor) combined with other bronchodilators in chronic obstructive pulmonary disease patients with reversibility (>150 mL to short-acting ...
Dave Singh, K. Abbott-Banner, T. Bengtsson, K. Newman   +3 more
semanticscholar   +1 more source

Clinical evaluation of nebulized verapamil in out‐patients with pulmonary hypertension secondary to chronic obstructive pulmonary disease

The Clinical Respiratory Journal, Volume 16, Issue 12, Page 802-811, December 2022., 2022
Single dose nebulized verapamil inhalation showed improvement in V/Q mismatch throught increase FVC. Nebulized verapamil inhalation improved gas exchanged and increased spO2. Nebulized verapamil inhalation for out‐patients with pulmonary hypertension secondary to chronic obstructive pulmonary disease improved spirometric parameter.
Fanak Fahimi, Guitti Pourdowlat, Neda Behzadnia, Sahar Sadigh Mostofi, Aida Sefidani Forough, Omid Parto, Ayda Esmaeili   +6 more
wiley   +1 more source

Possible Mechanisms Underlying the Antispasmodic, Bronchodilator, and Antidiarrheal Activities of Polarity–Based Extracts of Cucumis sativus L. Seeds in In Silico, In Vitro, and In Vivo Studies

Pharmaceuticals, 2022
Apart from the nutritional value, Cucumis sativus L. has also been used in the traditional medicine of Iran, Pakistan, and India. Its seeds are used by herbalists to treat gastrointestinal, respiratory, and urinary problems.
Muqeet Wahid, Fatima Saqib, Saeed Akhtar, Anam Ali, Polrat Wilairatana, Mohammad S. Mubarak   +5 more
doaj   +1 more source

Overprescription of short‐acting β2‐agonists among patients with asthma in Saudi Arabia: Results from the SABINA III cohort study

The Clinical Respiratory Journal, Volume 16, Issue 12, Page 812-825, December 2022., 2022
Results from the Saudi Arabia cohort of the SABINA III study demonstrated SABA over‐prescription (≥3 canisters/year) in more than 60% of patients with asthma, substantial over‐the‐counter purchase of SABA, and a high exacerbation burden. Our findings emphasize the need for a fundamental, paradigm shift in prescribing habits with a focus on alignment ...
Hamdan Al‐Jahdali, Siraj Wali, Amr S. Albanna, Abeer Al Harbi, Riyad Allehebi, Abdulmajed Arwadi, Tarek Dahan, Mohamed Fattouh, Ezzat Hamza, Maarten Beekman   +9 more
wiley   +1 more source