Results 11 to 20 of about 1,154,949 (367)
Loading and firing the brown adipocyte [PDF]
Adipocyte, 2017 Brown adipose tissue (BAT) is specialized to both store and expend chemical energy making it an ideal therapeutic target for various metabolic diseases.
M. Hankir
semanticscholar +3 more sources
Diet-Induced Adipocyte Browning [PDF]
Polish Journal of Food and Nutrition Sciences, 2021 The adipocyte browning process is a phenomenon that consists in the molecular and morphological remodeling of preadipocytes or mature white adipocytes into multilocular beige fat cells expressing thermogenesis-associated genes. Adipocyte browning may occur physiologically, mainly upon cold or exercise stimulation.
Oskar Wojciech Wiśniewski +3 more
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Epigenetic Regulators of White Adipocyte Browning [PDF]
Epigenomes, 2021 Adipocytes play an essential role in maintaining energy homeostasis in mammals. The primary function of white adipose tissue (WAT) is to store energy; for brown adipose tissue (BAT), primary function is to release fats in the form of heat.
Ravikanth Nanduri
doaj +3 more sources
Scientific Reports, 2022 Human brown fat is a potential therapeutic target for preventing obesity and related metabolic diseases by dissipating energy as heat through uncoupling protein 1 (UCP1).
Y. Takeda, P. Dai
semanticscholar +4 more sources
Characterization of immortalized human brown and white pre-adipocyte cell models from a single donor. [PDF]
PLoS ONE, 2017 Brown adipose tissue with its constituent brown adipocytes is a promising therapeutic target in metabolic disorders due to its ability to dissipate energy and improve systemic insulin sensitivity and glucose homeostasis.
Lasse K Markussen +8 more
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Nesfatin-1 promotes brown adipocyte phenotype [PDF]
Scientific Reports, 2016 Nesfatin-1, an 82 amino acid gastric peptide, is involved in regulation of food uptake and in multiple metabolic activities. Whether nesfatin-1 modulates the differentiation and lipid metabolism of brown adipocytes remains unknown.
Yuexin Wang +6 more
semanticscholar +3 more sources
Brown adipocyte glucose metabolism: a heated subject [PDF]
EMBO reports, 2018 The energy expending and glucose sink properties of brown adipose tissue (BAT) make it an attractive target for new obesity and diabetes treatments. Despite decades of research, only recently have mechanistic studies started to provide a more complete ...
M. Hankir, M. Klingenspor
semanticscholar +3 more sources
The brown adipocyte β-adrenoceptor [PDF]
Proceedings of the Nutrition Society, 1989 Jonathan R.S. Arch
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Follistatin promotes adipocyte differentiation, browning, and energy metabolism[S] [PDF]
Journal of Lipid Research, 2014 Follistatin (Fst) functions to bind and neutralize the activity of members of the transforming growth factor-β superfamily. Fst has a well-established role in skeletal muscle, but we detected significant Fst expression levels in interscapular brown and ...
Melissa Braga +13 more
doaj +5 more sources
Brown Adipose Tissue Heterogeneity, Energy Metabolism, and Beyond
Frontiers in Endocrinology, 2021 Brown adipocyte in brown adipose tissue (BAT) specializes in expending energy through non-shivering thermogenesis, a process that produces heat either by uncoupling protein 1 (UCP1) dependent uncoupling of mitochondrial respiration or by UCP1 independent
Abhijit Babaji Shinde +3 more
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