Results 11 to 20 of about 1,141,798 (294)
Lipid Transport in Brown Adipocyte Thermogenesis. [PDF]
Front Physiol, 2021 Non-shivering thermogenesis is an energy demanding process that primarily occurs in brown and beige adipose tissue. Beyond regulating body temperature, these thermogenic adipocytes regulate systemic glucose and lipid homeostasis.
Wade G, McGahee A, Ntambi JM, Simcox J.
europepmc +6 more sources
Loading and firing the brown adipocyte [PDF]
Adipocyte, 2017 Brown adipose tissue (BAT) is specialized to both store and expend chemical energy making it an ideal therapeutic target for various metabolic diseases.
M. Hankir
semanticscholar +4 more sources
Identification of brown adipocyte progenitors
, 2020 Today’s therapy against obesity uses life style changing and/or medication, but is little promising so far. Therefore it is important to develop new and successful therapeutically strategies against obesity. Nowadays brown adipose tissue gives hope to develop new therapeutically strategies and therapies against obesity because of its energy combusting ...
Verena Rau
semanticscholar +4 more sources
Extracellular calcium modulates brown adipocyte differentiation and identity
Scientific Reports, 2017 Brown adipocytes are important in regulating non-shivering thermogenesis, whole body glucose and lipid homeostasis. Increasing evidence supports an important role of metabolites as well as macro- and micronutrients in brown adipocyte differentiation and ...
Ines Pramme-Steinwachs +2 more
doaj +2 more sources
Epigenetic Regulators of White Adipocyte Browning [PDF]
Epigenomes, 2021 Adipocytes play an essential role in maintaining energy homeostasis in mammals. The primary function of white adipose tissue (WAT) is to store energy; for brown adipose tissue (BAT), primary function is to release fats in the form of heat.
Ravikanth Nanduri
doaj +3 more sources
Nesfatin-1 promotes brown adipocyte phenotype [PDF]
Scientific Reports, 2016 Nesfatin-1, an 82 amino acid gastric peptide, is involved in regulation of food uptake and in multiple metabolic activities. Whether nesfatin-1 modulates the differentiation and lipid metabolism of brown adipocytes remains unknown.
Yuexin Wang +6 more
semanticscholar +4 more sources
Regulation of white and brown adipocyte differentiation by RhoGAP DLC1. [PDF]
PLoS ONE, 2017 Adipose tissues constitute an important component of metabolism, the dysfunction of which can cause obesity and type II diabetes. Here we show that differentiation of white and brown adipocytes requires Deleted in Liver Cancer 1 (DLC1), a Rho GTPase ...
Choon Kiat Sim +9 more
doaj +2 more sources
Deconstructing cold-induced brown adipocyte neogenesis in mice. [PDF]
Elife, 2022 Cold-exposure triggers neogenesis in classic interscapular brown adipose tissue (BAT) that involves activation of b1-adrenergic receptors, proliferation of PDGFRA+ adipose tissue stromal cells (ASCs), and recruitment of immune cells whose phenotypes are ...
Burl RB +4 more
europepmc +2 more sources
Diet-Induced Adipocyte Browning [PDF]
Polish Journal of Food and Nutrition Sciences, 2021 The adipocyte browning process is a phenomenon that consists in the molecular and morphological remodeling of preadipocytes or mature white adipocytes into multilocular beige fat cells expressing thermogenesis-associated genes. Adipocyte browning may occur physiologically, mainly upon cold or exercise stimulation.
Oskar Wiśniewski +3 more
openaire +2 more sources
Cell Metabolism, 2010 We are pleased to present in this issue of Cell Metabolism a review series on brown adipocytes. Until recently, brown adipose tissue (BAT) was principally studied by a handful of investigators focused on rodents and newborn mammals, and, at times, their work was deemed more an exercise in scientific curiosity than an issue relevant to human health.
Charlotte Wang, Nikla Emambokus
openaire +3 more sources