Results 181 to 190 of about 39,242 (266)

Protocol for targeted gene manipulation and thermogenic evaluation in mouse brown adipocytes. [PDF]

STAR Protoc
Bunk J, Soni D, Calderon M, Samborska B, Kazak L.   +4 more
europepmc   +1 more source

Amelioration of Cancer Cachexia‐Induced Muscle Atrophy and Adipose Tissue Wasting by a Combination of Amaranth (Amaranthus caudatus L.) Hydrolysate and Korean Mint (Agastache rugosa) Extract in BALB/c Mice

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
Amaranth hydrolysate combined with Agastache rugosa extract (AKE) attenuated cancer cachexia in CT26 tumor‐bearing mice by suppressing systemic inflammation and modulating muscle and adipose tissue metabolism. AKE inhibited FoxO3a‐mediated proteolysis while restoring PI3K/Akt/mTOR‐dependent protein synthesis in skeletal muscle.
Junhee Lee, Junhui Kang, Sungmin Han, Ho‐Tak Jung, Daedong Kim, Dong‐Woo Lee, Jae‐Kwan Hwang   +6 more
wiley   +1 more source

Activation of Brown Adipocytes by Farnesoid X Receptor Agonist, Obeticholic Acid-A Potential Novel Therapeutic Avenue in the Management of Obesity. [PDF]

J Clin Med
Dąbrowska AM, Chwil M, Urbańska EM.
europepmc   +1 more source

Systemic and Local Adiposity in the Bone Marrow Microenvironment Associated With Improved Prognosis in Hodgkin Lymphoma: Imaging and Molecular Analysis

International Journal of Cancer, Volume 159, Issue 3, Page 782-796, 1 August 2026.
Schematic overview of systemic and bone marrow‐specific adiposity in Hodgkin Lymphoma (HL). Body Mass Index was associated with bone marrow (BM) involvement, relapse, and mortality (1). In contrast, increased yellow marrow density was associated with poorer prognosis (2).
Andreia Matos, William P. Cawthorn, Joana Marinho‐Dias, Sofia Ramalheira, Susana Roncon, Dulcineia Pereira, Teresa Ribeiro, Carla Rodrigues, Mário Mariz, Ana Miranda, Helena Brízido, Manuel Bicho, Pedro Medeiros, Ana Carneiro, Fernanda Trigo, Pingzhao Hu, Flávia Pereira, Hugo Duarte, Calum D. Gray, Tom Macgillivray, Alan G. Ramsay, Maria J. Oliveira, Ricardo Ribeiro   +22 more
wiley   +1 more source

KLF7 induced ADRB3-dependent IL-6 production in brown adipocytes during stress. [PDF]

J Lipid Res
Liang M, Zhang M, Hou Y, Yuan F, Zhang H, Zhao M, Xu L, Liu Q, Su Y, Chu X, Li W, Wang J, Xie J, Wang C, Cui Q, Zhang J.   +15 more
europepmc   +1 more source

Divergent AKT Signalling Mechanisms Regulate GLUT4 Translocation and Glucose Uptake in Skeletal Muscle and Adipose Tissue

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 4, August 2026.
ABSTRACT Background The serine/threonine kinase AKT is a key regulator of glucose and energy metabolism. Prevailing dogma suggests that AKT is an obligate intermediate for glucose uptake in all metabolic tissues and that impaired AKT signalling is a major molecular driver of insulin resistance in obesity.
Natasha Jaiswal, Matthew Gavin, Louise Lantier, Olivia Yu Yu Ong, David H. Wasserman, Paul M. Titchenell   +5 more
wiley   +1 more source

Protocol for measuring in vivo, ex vivo, and in vitro glucose uptake in brown adipocytes. [PDF]

STAR Protoc
Park CH, Chang JS.
europepmc   +1 more source

SIRT Family: Biological Functions and Therapeutic Targets

MedComm, Volume 7, Issue 8, August 2026.
SIRT1–SIRT7 networks from transgenic mice to human‑relevant therapeutic targets. SIRT1–SIRT7 form an isoform‑, organ‑, and disease‑specific regulatory network. Transgenic Sirt1–7 mouse models define central regulatory SIRTs (SIRT1, SIRT3, SIRT6), context‑dependent modifiers (SIRT2, SIRT4, SIRT5, SIRT7), and their key mechanisms and target organs. These
Jia‐Yi Wang, Feng‐Li Jiang, Fang‐Yuan Zhang, Dong‐Hui Huang, Xiao‐Ying Li, Song Gao, Hua You, Qi‐Jun Wu, Huan‐Huan Chen, Ting‐Ting Gong   +9 more
wiley   +1 more source

Multi-omics analysis of thermogenic lipolysis in brown adipocytes. [PDF]

iScience
Anagho-Mattanovich M, Anagho-Mattanovich HA, Argemi-Muntadas L, Nielsen ML, Gao Q, Moritz T.   +5 more
europepmc   +1 more source

ASK1‐Induced FGF21 Synthesis in the Liver Prevents Obesity in Mice

Obesity, Volume 34, Issue 8, Page 1635-1646, August 2026.
ABSTRACT Objective Fibroblast growth factor 21 (FGF21) is a stress‐induced hormone secreted by the liver. It has a beneficial role in the regulation of glucose and energy metabolism. Herein, we identify apoptosis signal regulating kinase 1 (ASK1) as an inducer of hepatic FGF21 synthesis.
Anne Goergen, Tenagne D. Challa, Carlos Villaroel‐Vicente, Marcela Borsigova, Pim P. van Krieken, Christian Wolfrum, Matthias Blüher, Stephan Wueest, Daniel Konrad   +8 more
wiley   +1 more source